clients across the globe achieve gene targeting and custom mouse model success with iTL
What You Need
Creative and Novel Mouse Models
iTL maintains the confident and creative mindset that if you can think it up, we can make it happen. Researchers work with us to make creative and novel mouse models that defy convention and present technical challenges that other mouse modelers won’t approach.
"You think it up, we knock it out" has been the iTL scientist's traditional working motto. However, with maturation of the field of genetically modified mice and the expansion of our core capabilities, our seasoned scientists do much more than just knocking-out genes.
Model refinements such as conditional knockouts and knockins with insertions such as human and murine cDNA, reporter genes, point mutations and targeted transgenes have taken our scientific teams to the forefront of gene targeting technology.
iTL has worked with our clients to achieve such models as:
Humanized mouse models
Mass deletions: 150kb
Multiple point mutations with spatial separation
Conditional point mutations activated in the tissue of interest
Conditional knockout with a reporter gene
Spatially separated double knockout
NEW! F.A.S.T. Knockin: A multi-purpose mouse line with the potential for five or more controllable functionalities. Learn More
Our accomplished scientists will work directly with you to make your model a practical reality and a uniquely tailored tool to help push your research to new levels of success.
For more information and pricing, please contact us