inGenious Targeting Laboratory
inGenious Targeting Laboratory
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clients across the globe achieve gene targeting and custom mouse model success with iTL
 
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GeneTargeting Quarterly e-Newsletter Q2, 2010
  In This Issue

 Industry News

 iTL News

 Client Publications

 Events

 Resources





 Links



 
 www.genetargeting.com

 Contact Us

 e-Mail Us

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 Quote Requests







iTL releases a new BALB/c custom mice service to immunology and medical researchers.  The BALB/c cell line has proven a strong resource in medical research, but with limited options.  The capability to produce BALB/c custom gene targeted mouse models opens up new avenues of investigation to researchers.











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News
Industry News
 
-- Affymetrix and Jackson Laboratory Launch First Genotyping Tool for Studying Mouse Strain Diversity

Affymetrix, Inc. (NASDAQ:AFFX) and The Jackson Laboratory today announced the full commercial launch of the Affymetrix® Mouse Diversity Genotyping Array. This is the first high-density genotyping array that enables researchers to study the complexity of the mouse genome and the diversity among mouse strains.
--  XenBio acquired by Taconic
Caliper Life Sciences, a Hopkinton, MA-based provider of life sciences research products and services, said today that it has sold its small animal services business, Xenogen Biosciences (XenBio), to the laboratory rodent provider Taconic Farms for about 11 million USD.

 
iTL News
 -- New BALB/c Cell and Animal Line Launched  
iTL releases a new BALB/c custom mice service to immunology and medical researchers.  The BALB/c cell line has proven a strong resource in medical research, but with limited options.  The capability to produce BALB/c custom gene targeted mouse models opens up new avenues of investigation to researchers.
--  3 Year Agreement with Top 10 Pharma Company
iTL announced the establishment of a master service agreement with a top 10 pharmaceutical company.  This 3 year agreement leverages iTL's experience of delivering nearly one thousand custom mouse models and scalable production capacity to create genetically tailored mice for the big pharma company.
--  New Website Platform
iTL launched a new website marking the first release of its brand and priorities for the new decade.  In its 12th year of business, iTL is re-focusing and re-committing to delivering exceptional service and client experience through every client interaction.
 
 
Client Publications
 
-- Modulation of Angiotensin II–Mediated Cardiac 
   Remodeling by the MEF2A Target Gene Xirp2
   Project Type: 129SvEv Conditional Knockout
 
-- ADAM10 essential for Notch2-dependent marginal  
   zone B cell development & CD23 cleavage in vivo
   Project Type: C57BL/6 Conditional Knockout
-- ZFP191 is required by oligodendrocytes for CNS myelination
   Project Type: C57BL/6 Conditional Knockout
 
-- Human TUBB3 mutations perturb microtubule dynamics, kinesin  
   interactions, and axon guidance.
   Project Type: 129SvEv Conditional Knockout; 129SvEv Knockin
 
 
 
Events
--  Immunology 97th Annual Meeting
May 7-11, Baltimore, MD, USA
 
iTL will attend Immunology. Come speak with us at our booth and learn about a new BALB/c line
Contact us to schedule a meeting at the event
 
--  BIO Annual Meeting                             May 3-6, Chicago, IL, USA
--  BioConference Live                              June 2-3, On-line, global
--  FASEB SRC: Transfer ATPases             June 6-11, Snowmass, CO, USA
--  Society fer Developmental Biology      Aug. 5-9, Albuquerque, NM, USA
--  Life Sciences Summit                          Sep. 21-22, Long Island, NY, USA
 
 
Resources
 
--  Discussion Forums
Gene targeted and transgenic mouse based researchers spend a lot of time and resources in this niche community we all share.  It comes as no surprise to then find out that many of us are turning to each other for information, suggestions and guidance. 
 
Below are three free peer communication resources we have found informative and believe you may find useful too.
- MGI List Serv : Jackson Labs Mouse Genome Informatics e-mail List Service
- ISTT Blog : International Society for Transgenic Technologies blog and forum
- TGL : Transgenic List discussion group out of Imperial College, London
 
--  Knockout Mouse Article Publication Grapher
Have you ever presented a graph of the number of publications of a particular type of mouse models over time?  Knockoutscience.com thinks that you have and that you will probably want to again.
 
Their graph generating tool allows you to input a mouse strain or knockout/in type and see the publication volume over time.

Client Quote of the Quarter
"I worked with iTL on the generation of a conditional knockout mouse strain for a complex gene.  I have been very impressed by their flexibility and their efficienty in completing each steps with no delays.  I'm glad to share this experience and highly recommend iTL's services."

Sponsorship
iTL proudly sponsors the TransGenic-List and ISTT