Creative and Novel Mouse Models
iTL maintains the confident and creative mindset that if you can think it up, we can make it happen. Researchers work with us to make creative and novel mouse models that defy convention and present technical challenges that other mouse modelers won’t approach.
"You think it up, we knock it out" has been the iTL scientist's traditional working motto. However, with maturation of the field of genetically modified mice and the expansion of our core capabilities, our seasoned scientists do much more than just knocking-out genes.
Model refinements such as conditional knockouts and knockins with insertions such as human and murine cDNA, reporter genes, point mutations and targeted transgenes have taken our scientific teams to the forefront of gene targeting technology.
iTL has worked with our clients to achieve such models as:
- Mass deletions: 150kb
- Multiple point mutations with spatial separation
- Conditional point mutations activated in the tissue of interest
- Conditional knockout with a reporter gene
- Spatially separated double knockout
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Our accomplished scientists will work directly with you to make your model a practical reality and a uniquely tailored tool to help push your research to new levels of success.
