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Publications

The ability to publish your results in globally respected peer reviewed journals is critical to your success. Since our first customer published their research (Science, 2001), iTL customers have published over 100 articles in the world’s highest profile publications using their iTL custom mouse models.

Our customers have published numerous times in journals such as Nature, Science, Cell, PNAS, and the Journal of Biological Chemistry.  Leading the scientific community by pairing your novel ideas with our seasoned gene targeting experience is what fuels iTL’s and our customers’ passion to work together.

 


Below are just a few of the recent publications resulting from the accomplishments of iTL customers using their iTL custom gene targeted mouse models.

2008-2009 publications

Generation of mouse conditional and null alleles of the type III sodium-dependent phosphate cotransporter PiT-1. (2009)
Festing MH, Speer MY, Yang HY, Giachelli CM.
Department of Bioengineering, University of Washington, Seattle, Washington.
Genesis. 2009 Oct 30. [Epub ahead of print]

Mouse Cofactor of BRCA1 (Cobra1) Is Required for Early Embryogenesis (2009)
Amleh A, Nair SJ, Sun J, Sutherland A, Hasty P, Li R.
Plos One. 2009;4(4):e5034. Epub 2009 Apr 2

Sphingomyelin Synthase 2 Is One of the Determinants for Plasma and Liver Sphingomyelin Levels in Mice (2009)
Liu J, Zhang H, Li Z, Hailemariam TK, Chakraborty M, Qui D, Bui HH, Peake DA, Kuo MS, Wadgaonkar R, Cao G, Jiang XC.
Arterioscler Thromb Vasc Biol. 2009 Mar 12. [Epub ahead of print]

Reduced proliferative activity of primary POMGnT1-null myoblasts in vitro (2009)
Yuko Miyagoe-Suzuki, Nami Masubuchia, Kaori Miyamoto, Michiko R. Wadaa, Shigeki Yuasac, Fumiaki Saitod, Kiichiro Matsumurad, Hironori Kanesakie, Akira Kudoe, Hiroshi Manyaf, Tamao Endof and Shin’ichi Takeda
Mech Dev. 2009 Mar-Apr; 126(3-4): 107-16.

DNA Polymerase δ Is Required for Early Mammalian Embryogenesis (2009)
Arikuni Uchimura, Yuko Hidaka, Takahiro Hirabayashi, Masumi Hirabayashi, Takeshi Yag
Plos One. 2009; 4(1): e4184.

Targeted Knockout of the Mouse βB2-crystallin Gene (Crybb2) Induces Age-Related Cataract (2008)
Jun Zhang, Jing Li, Caiguo Huang, Lian Xue, Yajun Peng, Qing Fu, Li Gao, Jianrong Zhang, and Wenjie Li
Invest Ophthalmol Vis Sci. 2008 Dec; 49(12): 5476-83.

Complementation in trans of altered thymocite development in mice expressing mutant forms of the adaptor molecule SLP76 (2008)
Jordan, M.S., Smith, J.E., Burns, J.C., Austin, J.E., Nichols, K.E., Aschenbrenner, A.C., Koretzky, G.A.
Immunity. 2008 Mar; 28(3): 359-69.

Secreted frizzled related protein 1 is a paracrine modulator of epithelial branching morphogenesis, proliferation, and secretory gene expression in the prostate. (2008)
Joesting, MS., Cheever, TR., Volzing, KG., Yamaguchi, TP., Wolf, V., Naf, D. Rubin, J.S., Marker, PC.
Dev Biol. 2008 May 1; 317(1): 161-73.

The Calcium Channel TRPV6 is Involved in Murine Maternal-Fetal Calcium Transport (2008)
Suzuki, Y., Kovacs, CS., Takanaga, H. Peng, J.B., Landowski, CP., Hedinger, MA.
J Bone Miner Res. 2008 Aug; 23(8): 1249-56.

Epithelial cells remove apoptotic epithelial cells during post-lactation involution of the mouse mammary gland (2008)
Monks, J., Smith-Steinhart C., Kruk ER., Fadok, VA., Henson, PM.
Biol Reprod. 2008 Apr; 78(4): 586-94.

The PIAS-Like Protein Zimp10 Is Essential for Embryonic Viability and Proper Vascular Development (2008)
Beliakoff, Jason., Lee, Jane.,Ueno, Hiroo., Aiyer, Aparna., Weissman, Irving L., Barsh, Gregory S., Cardiff, Robert D., Sun, Zijie.
Mol Cell Biol. 2008 Jan; 28(1): 282-92.

A Novel Role of Sprouty 2 in Regulating Cellular Apoptosis (2008)
Edwin, F., Patel, T.B.
J Biol Chem. 2008 Feb 8; 283(6): 3181-90.

Retinopathy in mice induced by disrupted all-trans-retinal clearance (2008)
Akiko Maeda, Tadao Maeda, Marcin Golczak and Krzysztof Palczewski
J Biol Chem. 2008 Sep 26; 283(39): 26684-93.

DEC1 Modulates the Circadian Phase of Clock Gene Expression (2008)
Ayumu Nakashima, Takeshi Kawamoto, Kiyomasa K. Honda, Taichi Ueshima, Mitsuhide Noshiro, Tomoyuki Iwata, Katsumi Fujimoto, Hiroshi Kubo, Sato Honma, Noriaki Yorioka, Nobuoki Kohno and Yukio Kato
Mol Cell Biol. 2008 Jun; 28(12): 4080–92.

Defining the Importance of Phosphatidylserine Synthase-1 (PSS1) (2008)
Devi Arikketh, Randy Nelson, and Jean E. Vance
J Biol Chem. 2008 May 9; 283(19): 12888-97.

A Role for GCAP2 in Regulating the Photoresponse Guanylyl Cyclase Activation and Rod Electrophysiology in Guca1b Knock-out Mice (2008)
Clint L. Makino, Igor V. Peshenko, Xiao-Hong Wen, Elena V. Olshevskaya, Ronald Barrett, and Alexander M. Dizhoor
J Biol Chem. 2008 Oct 24; 283(43): 29135-43.

H2S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine γ-Lyase (2008)
Guangdong Yang, Lingyun Wu, Bo Jiang, Wei Yang, Jiansong Qi, Kun Cao, Qinghe Meng, Asif K. Mustafa, Weitong Mu, Shengming Zhang, Solomon H. Snyder, Rui Wang
Science. 2008 Oct 24; 322(5901): 587-90.

Sphingomyelin Synthase 2 Deficiency Attenuates NFB Activation (2008)
Tiruneh K. Hailemariam; Chongmin Huan; Jing Liu; Zhiqiang Li; Christopher Roman; Michael Kalbfeisch; Hai H. Bui; David A. Peake; Ming-Shang Kuo; Guoqing Cao; Raj Wadgaonkar; Xian-Cheng Jiang
Arterioscler Thromb Vasc Biol. 2008 Aug; 28(8): 1519-26.

Retinyl Ester Homeostasis in the Adipose Differentiation-related Protein-deficient Retina (2008)
Yoshikazu Imanishi12, Wenyu Sun1, Tadao Maeda, Akiko Maeda, and Krzysztof Palczewski
J Biol Chem. 2008 Sep 5; 283(36): 25091-102.

Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin (2008)
Yvonne Lüke, Hafida Zaim, Iakowos Karakesisoglou, Verena M. Jaeger, Lorenz Sellin, Wenshu Lu, Maria Schneider, Sascha Neumann, Asa Beijer, Martina Munck, V. C. Padmakumar, Joachim Gloy, Gerd Walz and Angelika A. Noegel
J Cell Sci. 2008 Jun 1; 121 (Pt 11): 1887-98.

 

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