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Humanized

Humanized Mice

Humanized Mice

This content is available for informational purposes, intended for those who are interested in working with mouse models to further their research. Humanized Mice: Use Cases for Studying Human Immunity With the advancement of modern techniques and technologies used for genetic manipulation, humanized mice have become an important asset in the field of genetic research. […]

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Why Make A Humanized Mouse?

Why Make a Humanized Mouse?

Humanized Mouse Models The mouse has been used for over 30 years as a model system for studying human disease. Recently, “humanized” mice have grown in popularity because they are formidable models of the human being and therefore extremely useful for understanding the human condition. What exactly is a humanized mouse? A humanized mouse is […]

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Brain Health, Iron Levels And Oxidative Stress – A Delicate Balance

Brain Health And Iron Levels – A Delicate Balance

Understanding Brain Health Building and maintaining a healthy brain requires thousands of distinct processes to be exquisitely balanced throughout decades of life. Extensive research in recent decades has found this equilibrium is disrupted in brains that are aging or undergoing degeneration. However it isn’t clear whether these disturbances are a cause or a consequence of […]

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Humanization of Larger Animal Models

humanization

Humanization of Custom Rabbit Models A major bottleneck in researching human disease and developing new drugs is the lack of larger animal models that more accurately simulate human disease in the pre-clinical setting. The advantages of developing better models for human biology become clearer every day, especially including improved chances of translating research from animal […]

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Humanized Mice Used In Newborn Jaundice Research

Newborn Jaundice Research

Advanced Treatments Aiming to Stop the Development of Newborn Jaundice A condition known as jaundice is responsible for many health risks and problems involving newborn babies, particularly in lesser developed countries throughout Africa and South Asia, where treatments such as blood transfusions are not as readily available as in developed countries. Newborn jaundice is caused […]

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ZIKV Mouse Model 

ZIKV Mouse Model

Studying the Zika Virus with a New ZIKV Mouse Model The Zika virus, also known as ZIKV, has become notorious in Brazil, where it had spread during 2015, infecting thousands of people. The main risk of the virus is in its association with the Cuillain-Barre Syndrome, a rare autoimmune disease that can cause microencephaly in […]

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