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From theoretical concept to experimental reality, ingenious has delivered mouse models

advancing the research of over 900 laboratories worldwide.

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Full Service Model Creation

Our proprietary process allows us to produce the models you need, custom CRISPR rodent models, with 100% certainty.  With predictable timelines, a price that fits your budget, and our promise to you – Guaranteed Delivery of your mouse model – ingenious will succeed for you where others have failed.

A full-service project from ingenious will apply the power of the CRISPR/Cas9 system to your project, with assured results. Our scientists are backed by almost 20 years of experience and will create custom targeting strategies for your gene of interest.  Our track record allows us to guarantee delivery of the mice you need, giving us the confidence to call our proprietary service- ingenious CRISPR 100% 

The power of CRISPR/Cas9, the certainty you need.


Project Evaluation & Initiation

Together we carefully evaluate your needs and research goals and translate them into personalized project parameters for your particular mouse model. Before a project is initiated, the gene of interest is thoroughly evaluated at no extra cost.

The ingenious CRISPR 100% Service

  •  Streamlined project design and communication- Most projects can start within just one hour communication.
  • It uses minimal amount of animals. No exhausting mating is needed to reach germline transmission, which saves you time and money.
  • It is a model delivery guaranteed, different than a money back guarantee which does not guarantee a model. We understand fully that you come to us for getting your model done.
  • The timeline with our proprietary technology is better than classical conditional CRISPR approach.
  • Proof is in the publications – We have a long history in the industry >20 years backed by hundreds of gene targeting publications
  • All work is performed in the USA



Recent Client Publications!

Congratulations to our Clients Congratulations to our Clients Dr. Douglas Gould from UCSF School of Medicine, Dr. Ichizo Nishino from National Institute of Neuroscience, Japan, & Dr. Jian-xing Ma from University of Oklahoma Health Sciences Center. Their research and publications included the use of conditional knockout models, and point mutation knockin mouse models from ingenious. They now are among the hundreds
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Gene Therapy and Usher Syndrome

The Promising Results in Using Gene Therapy to Treat Usher Syndrome Patients Gene therapy has advanced considerably in recent years, due particularly to mutant mouse models genetically modified to mimic the effects of health problems like deafness and help test effective treatments. Various studies published this February in Nature Biotechnology showed the progress researchers have
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Breakthrough in CRISPR Technology

A Breakthrough Step to a More Accurate and Targeted Use of the CRISPR Gene Editing Tool Despite the many revolutionary breakthroughs that scientists have obtained with the CRISPR gene editing tool, there have been many difficulties when it came to limiting its reach and preventing accidental gene alteration. This is about to change due to
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“I worked with ITL on the generation of a conditional knockout mouse strain for a complex gene. I have been very impressed by their flexibility and their efficiency in completing each steps with no delays. I’m glad to share this experience and highly recommend ITL’s services.”

-Frédéric Marmigère, PhD