"A better model is within reach."

Disease research

Point Mutation Diseases

Point Mutation Diseases

The Main Point Mutation Diseases That Can and Should Be Studied When it comes to the study of disease through genetic means, point mutation diseases are among the most important to consider. Whether we’re talking about single or multiple point mutations, the protein function that is affected by these types of mutations can range from […]

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Humanized Mice

Humanized Mice

What Are Humanized Mice and Why Are They Really Used? With an increase in the advancement of modern techniques used for genetic manipulation, humanized mice have become an important asset. These mice are used to mimic human conditions and apply potential therapies more efficiently, without any of the risks involved with using human patients. Also, […]

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Transgenic Mouse Model

Transgenic Mouse Model

The Benefits and Drawbacks of the Transgenic Mouse Model When Modeling Human Disease When it comes to evaluating the benefits and disadvantages of using a transgenic mouse model to test a hypothesis about disorders affected by genetics, there are many important points to remember. Importantly, transgenic models can be highly effective in evaluating the reason […]

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Transgenic Mice

Transgenic Mice

What Are Transgenic Mice and Why Are They Important in Genetic Research? When considering the drugs we take to alleviate the symptoms of disease, never would we have imagined how important transgenic laboratory mice are to drug development. However, these mice are of pivotal importance in the genetic research necessary to achieve the relief we […]

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Gene Knockin Mouse

gene knockin

By Jennifer Parla, Ph.D. Aha! I Need a Knockin Mouse… Now What? Moving to animal studies At the start of your research, a live animal model may not have been necessary. You may have been studying a biochemical pathway or process that is highly conserved and can be investigated using cultured cells or sometimes with cell-free […]

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CRISPR Mice

Crispr Mice by INGENIOUS

The Prospect of Using CRISPR Mice and the Future of Medical Research Many new breakthroughs were possible through the use of CRISPR mice. The CRISPR technique is one of the most groundbreaking new achievements in genetic research, and it works remarkably well to achieve knockout and transgenic mouse models for genetic research purposes. For anyone […]

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Knockout Mice Purpose

Knockout Mice Purpose by INGENIOUS

Researching Knockout Mice – Purpose and Understanding of Long Term Benefits When it comes to knockout mice, their purpose in research has already had a profound effect on our understanding of human genetics. We’re uncovering the underlying causes of conditions like cancer, diabetes, heart disease and many other debilitating disorders. Genetic research conducted on mice […]

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Knockin Mice

Knockin Mice by INGENIOUS

Knockin Mice and Their Remarkably Crucial Role in Studying and Fighting Disease Knockin mice are the leading edge when it comes to the research of genetic diseases and genetic sequences that could hold the key to accelerating or stopping some of the most debilitating diseases known to man. Much progress has already been achieved in […]

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Knockout Mice In The Study Of Human Genetic Disease

genetic disease

Knockout Mice and Their Role in Disease Research Our understanding of human health and disease has been advanced immeasurably by research using knockout mouse models. In the thirty years since targeted gene knockouts were first demonstrated, thousands of these models have been created. For many human genetic diseases a specific gene is found to be […]

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Humanized Mouse Assists Cytokines Therapy

Humanized Mouse in FA Research

New Friedreich’s Ataxia Humanized Mouse Model Study Assists Cytokines Therapy A new study has recently appeared in Annals of Neurology, showing how neuroprotective results were obtained in a Friedreich’s Ataxia (FA) model. The mouse model in question was treated with clinically approved cytokines used for other diseases, and the results showed that future research using […]

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Reducing The Effects Of Emphysema

Reducing The Effects Of Emphysema

New Hope for COPD Patients: A Saccharide-Based Treatment That Could Reduce the Effects of Emphysema With the help of a new mouse model, scientists have recently managed to find a sugar molecule that could have the potential of reducing the progress of emphysema and significantly diminish the negative effects of COPD (chronic obstructive pulmonary disease). […]

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