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Knockin mice

Client Success With Knockin Mouse Model

Point Mutation Knockin Mouse Model Brings Client Success

Point Mutation Knockin Mouse Model Brings Client Success Dr. Virginia Kimonis started her career as a pediatrician in the UK and United Arab Emirates, where she encountered a number of patients with rare genetic diseases. These experiences motivated her to pursue training as a clinical geneticist at the National Institutes of Health. She also trained […]

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3 Things I Wish I Knew Before Making My First Knockin Mouse Model

knockin mouse model

My First Knockin Mouse Model Creating a new mouse model is a major step in any research program. Some things may have come to mind such as, “Can’t I finish this project using models that already exist?” or “Will I ever graduate if I undertake a knockin mouse model project?” If you have reached a […]

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Expand the Possibilities of Humanized Models

humanized models

…Beyond the Coding Sequence. Human genetic sequences have been routinely inserted into the mouse genome since the early 1980s when reliable methods were first developed. These genetically humanized models were quickly recognized as a means to study human diseases or produce specific valuable human proteins. Recent method development has expanded the possibilities for genetic humanization and […]

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The Value Of Knockout Mouse Models

The Value Of Knockout Mouse Models

A Detailed Analysis of the Price and Value of Knockout Mouse Models According to a recent report on the pricing analysis of knockout mouse models, there are many more factors involved in determining the monetary value of the mice, aside from the importance of the research studies they are used in. Demand, availability, the complexity […]

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CRISPR Mice

CRISPR Mice Deliverable

When it Comes to CRISPR Mice, What Exactly is Your Deliverable? The production of genetically modified mouse models is changing faster than ever thanks to CRISPR/Cas9 gene editing. With multiple approaches available for generating knockout or knockin mice, it is important to understand exactly what the deliverable is, and what needs to be done after […]

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