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Transgenic mice

Transgenic Mouse Model

Transgenic Mouse Model

The Benefits and Drawbacks of the Transgenic Mouse Model When Modeling Human Disease When it comes to evaluating the benefits and disadvantages of using a transgenic mouse model to test a hypothesis about disorders affected by genetics, there are many important points to remember. Importantly, transgenic models can be highly effective in evaluating the reason […]

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Transgenic Mice

Transgenic Mice

What Are Transgenic Mice and Why Are They Important in Genetic Research? When considering the drugs we take to alleviate the symptoms of disease, never would we have imagined how important transgenic laboratory mice are to drug development. However, these mice are of pivotal importance in the genetic research necessary to achieve the relief we […]

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BAC Transgenic

BAC Transgenic

An Overview of BAC Transgenic Mice – BAC Constructs and Their Uses BAC transgenic mice are an invaluable tool for research as demonstrated by decades of use across many fields of study. Understanding the potential uses of these models can expand the possibilities of an ongoing research project. So let’s take a closer look at […]

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CRISPR Transgenic Mice

Crispr Transgenic Mice by INGENIOUS

The Simplicity of Using CRISPR: Transgenic Mice and Genetic Research Since the development of CRISPR, transgenic mice are easier to obtain than ever, and CRISPR techniques have brought many new opportunities for research in the scientific community. Designed to create quick and efficient changes within DNA, gene editing systems such as CRISPR/Cas9 are extremely popular […]

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A New Mouse Line For Tissue-Specific Expression

transgenic knockin

By Richard Row, Ph.D. Transgenic Knockin Approaches Mouse models with tissue-specific expression of a reporter gene or Cre recombinase are powerful and commonly-used tools for research. The same transgenic knockin strategies used to make such lines can also be used for tissue-specific expression of almost any gene. For example, lines for controlled expression of a […]

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4 Reasons To Use Targeted Transgenic Mice Over Random Insertion

reasons to use transgenic mice

By Jennifer Parla, Ph.D. Don’t Leave Your Research Up To Chance Our study of biology has benefited greatly from the ability to create gene constructs and express them at the cell or organism level. While introducing and establishing gene expression constructs in cells may be more straightforward and can be less rigorous in methodology or […]

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New Service ingenious CRISPR 100%

ingenious CRISPR

We’re welcoming 2018 with the introduction of our innovative new service: ingenious CRISPR 100%. Our scientists use the latest advances in CRISPR/Cas9 targeting, utilizing simultaneous production steps, and backed by almost 20 years of successful mouse model delivery to safeguard the production of your rodent model. Our proprietary process allows us to produce the models […]

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Incredible Results Of Drug On Alzheimer’s Transgenic Mouse Model

transgenic mouse model

Diabetes Drug Tested in Alzheimer’s Mice “Significantly Reversed Memory Loss.” A drug developed for type 2 diabetes could be an effective way to treat Alzheimer’s disease. In recent research done in the UK, a drug developed for diabetes was tested in a transgenic mouse model of Alzheimer’s disease and showed significant improvement in neurocognitive function, […]

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Dawn Of The Zombie Cells

transgenic mouse

Transgenic Mouse Model Study and the Zombie Cells Oh, the beauty of ageing. The hair loss, the wrinkling of our skin, the loss of our eyesight, our diminishing cognitive memory…what joys. We’re all looking forward to it, right? Well, I guess not, but on the bright side, there might be some interesting breakthroughs to reverse […]

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New Mouse Model In Neurological Study

New Mouse Model In Neurological Study

A New Mouse Model for Studying Brain Cell Activity and Neurological Disorders According to a brand new study on transgenic mice and the selective targeting of astrocytes that has recently appeared in the journal Neuron, scientists have developed a revolutionary new mouse model. This is a breakthrough research tool for studying the activity of astrocytes […]

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Journey Of The Oncomouse

Journey Of The Oncomouse

The First Genetically Engineered Mouse Used to Fight Cancer Now held in the Smithsonian Institution among millions of other historically significant objects and documents, the Oncomouse – known as the first transgenic mammal to be subject to a US patent – has played a key role in recent scientific history. The mouse was first announced […]

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