ingenious Targeting Laboratory (ingenious) specializes in creating advanced genetically engineered animal models for academic and commercial researchers worldwide. We deliver high-quality, germline-confirmed models built to your specifications — with pricing you can lock in today to secure your budget and timeline.
Custom Mouse Models – Guaranteed Germline-Confirmed Mice
We offer a full range of services from simple knockouts to complex TruHumanization™ models. Lock in this pricing now and accelerate your research with proven, guaranteed results.
Rosa26 Transgenic Knock-ins
Knockouts and point mutations. Control where and when your gene of interest is inactivated, add a reporter to label affected cells. Make a new tissue-specific Cre or reporter line, or express a cDNA in place of another gene.
Target large regions for conditional deletion. Strong GFP expression labels cells where knockout occurs independent of native promoter.
Target gene initially expresses wild-type sequence which switches to mutant sequence when Cre is expressed. Hybrid (129 x C57BL/6).
Conditional Point Mutation
Replace part of the genome — up to 200kb — with human sequence. Study the promoter and splicing of human genes. Hybrid (129 x C57BL/6).
TruView™ Conditional Knockout
Target large regions for conditional deletion. Strong GFP expression labels cells where knockout occurs independent of native promoter.
Replace part of the genome — up to 200kb — with human sequence. Study the promoter and splicing of human genes. Hybrid (129 x C57BL/6).
Complex mouse models — an Ingenious specialty.