Entire Gene Replacement

With TruHumanization™ Technology

Take Your Research Further

Customized Lines Without Limitations.

Successful Disease Research

High Impact Research With Disease Models From ingenious

Your Research Deserves the Best


Join 90% of the world’s top bioscience institutions

Over 19 Years of Experience

Over 1,700 Completed Projects

Leader in Genome Editing & Cutting-Edge Technology

“You think it up, we knock it out… or in.”

Trusted Precision

Exactly what you need, our experts make it happen.

Fast Timelines

Guaranteed germline in less time than ever before.

Assured Quality

The quality you need, the value you seek.

Advancing Research

Our innovative technology has accelerated the research of over 900 laboratories.

CRISPR – Mouse Models

CRISPR Technologies from ingenious

As the field of genetically modified mouse models continues to advance, CRISPR gene editing will undoubtedly be at the forefront.


We offer CRISPR technologies that provide you with custom designed models that are produced quickly and efficiently without sacrificing precision and quality.  Learn more about our CRISPR services

Humanized MODELS

Trust ingenious to Fully Humanize Your Target Gene


“From a single base change to replacement of a 200kb mouse gene with human in a single step.”

Click to learn more about generating humanized mice models using our exclusive TruHumanization™ Technology.

“I’ve been working with iTL over the past 5 years in the production of 3 different genetically altered mice. Not only did iTL help in the design of the mice, but the entire process was transparent with the opportunity at any time along the way to discuss my questions or concerns with scientists who had significant insight into the process. The mice were delivered on time, as billed!”

Raghu Mirmira, MD, PhD

Indiana University

“ingenious was very competitively priced compared to other reputable transgenic companies. Most importantly, however, from the very beginning their knowledge and competence convinced me they would deliver on our project, so I trusted them and they fully met our expectations. Why use anyone else!”

Murray Clarke, PhD

University of Cambridge



With an ingenious design, any model is possible.