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Resources

Mouse Model Resources

ingenious targeting laboratory provides comprehensive resources to help researchers design, implement, and optimize custom mouse model projects.

From selection guides that clarify strategic decisions to technical resources and FAQs answering common questions, these resources draw on our experience from more than 2,500 projects completed since 1998.

2,500+
Projects Completed
800+
Publications
26+
Years Experience
100%
Success Rate
New for 2026

Breeding Scheme Architect

Plan complex single allele breeding schemes with our free interactive tool. Visualize breeding paths, calculate expected genotype ratios, and estimate time to experimental cohorts for knockout, knockin, Cre lox, and humanized mouse models.

Visualize breeding paths
Punnett square calculations for up to 6 alleles
Timeline and resource estimates
AI powered breeding optimization
Export schemes as PDF
Launch Breeding Scheme Architect

Free to use • No account required

Gated Resources

Downloadable Resources

All the information you need about our animal models in one place. For your convenience, ingenious has created software, quick guides, and charts with information on the different types of animal models we offer.

Need help choosing the right resource for your project?

Request a Consultation

Selection Guides

Strategy Guides

Making the right design decisions early in your project maximizes research value and minimizes timeline. These guides help you navigate key strategic choices:

Technical Resources

Technology Documentation

Detailed technical information about ingenious targeting laboratory's gene targeting approaches:

Publications

ingenious targeting laboratory generated mouse models have contributed to more than 800 peer reviewed publications across all major therapeutic areas and journals including Nature, Cell, Science, and specialty publications.

Searchable archive by therapeutic area
Publications organized by model type
Recent high impact publications
Full citation information

What Researchers Say

The Hephaestin flox model ingenious has made for us has been great. It has helped generate eight research publications.

Joshua Dunaief, PhD, MD

University of Pennsylvania

View All Testimonials

Video Library

Educational videos covering gene targeting concepts, project workflows, and technical approaches:

  • Understanding Conditional Knockouts
  • Project Planning Webinar Series
View Video Library

Glossary

Technical terminology reference for gene targeting and mouse genetics:

  • Allele nomenclature conventions
  • Recombinase system terminology
  • ES cell and mouse genetics terms
  • Project phase definitions
View Glossary

Start Your Project

Ready to discuss your research goals? Our scientific consultants provide complimentary project design consultations to help you plan the optimal mouse model strategy.

✦ New for 2026

Breeding Scheme Architect

Plan complex single allele breeding strategies, calculate expected genotype ratios, and estimate time to experimental cohorts—all before starting your project.

Visualize breeding paths
Calculate Mendelian ratios automatically
Estimate timeline to study ready cohorts

Free Research Tool

No account required

Allele 1Gene-flox (conditional)
Allele 2Cre-driver (tissue-specific)
TargetHomozygous knockout

→ 3 generations to target genotype

Lab Signals

Expert Research Insights Delivered

Subscribe to Lab Signals for biweekly articles on mouse model design, gene targeting best practices, and research insights from our PhD scientists.

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Frequently Asked Questions

We provide comprehensive resources including selection guides (knockout strategy, conditional vs conventional, humanization strategy, reporter selection, Cre line selection), planning guides (model generation timeline, budgeting guide), technical resources, and FAQs addressing common project questions.

Use the knockout or knockin strategy guide to compare global knockout, conditional knockout, and knockout-first approaches. Selection depends on whether the gene is essential (conditional avoids lethality), whether tissue-specific studies are needed (conditional enables spatial control), and whether temporal control is required (inducible conditional). Our scientific consultants provide complimentary consultation to help select optimal strategies.

Technical resources including selection guides, planning guides, and FAQs are available in the resources section. Our scientific consultants also provide complimentary project design consultations to help plan optimal mouse model strategies. Contact us through the request quote form or schedule a consultation.

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Colony Management ServicesCryopreservation ServicesMouse Genotyping ServicePhenotyping Services