What is Rapid Rosa26 targeting and how does it work?

Rapid Rosa26 targeting is an optimized gene targeting technology for inserting transgenes into the Rosa26 safe-harbor locus. The technology uses streamlined targeting vectors and workflows to reduce timelines while maintaining high-quality targeting and pre-germline characterization.

What types of transgenes can be inserted into Rosa26?

Rosa26 can accommodate various transgenes including reporters (GFP, luciferase, LacZ), Cre recombinase, inducible systems (CreER, TRE-driven expression), and other transgenes. Rosa26 provides ubiquitous expression with stable integration and minimal position effects.

How does Rapid Rosa26 compare to standard Rosa26 targeting?

Rapid Rosa26 uses optimized targeting strategies and streamlined workflows to reduce project timelines while maintaining the quality advantages of ES cell targeting. Contact us to discuss how Rapid Rosa26 can accelerate your specific project.

Our Services

Rapid ROSA26 Targeting

ingenious targeting laboratory's Rapid Rosa26™ technology accelerates transgenic model generation through established protocols and proven vector backbones. This proprietary approach enables shorter timelines while maintaining reliable, high quality models with predictable expression patterns.

Rosa26 remains the most widely used safe harbor locus for targeted transgenics due to its strong ubiquitous expression, well characterized regulatory elements, and minimal positional effects. Rapid Rosa26™ targeting leverages decades of experience with Rosa26 to streamline project execution.

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2,500+

Projects Completed

800+

Publications

26+

Years Experience

100%

Success Rate

✦ New for 2026

Breeding Scheme Architect

Plan complex single allele breeding strategies, calculate expected genotype ratios, and estimate time to experimental cohorts—all before starting your project.

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Visualize breeding paths

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Calculate Mendelian ratios automatically

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Estimate timeline to study ready cohorts

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Allele 1Gene-flox (conditional)

Allele 2Cre-driver (tissue-specific)

TargetHomozygous knockout

→ 3 generations to target genotype

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Our scientific consultants are ready to discuss your research requirements and recommend the optimal approach for your program. Initial consultation is provided at no charge.

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