Types of Rat Models Available
Conventional Knockout
Standard gene deletion for loss-of-function studies
Knockout/Reporter Knockin
Gene deletion with integrated reporter for visualization
Cre-conditional Knockout
Tissue-specific or inducible gene deletion using Cre-lox
Point Mutation Knockin
Precise base pair changes for disease modeling
Reporter Gene Knockin
Fluorescent or enzymatic reporters for expression tracking
Humanized cDNA Knockin
Human gene sequences for translational research
Available Rat Strains
Gene targeting available in diverse rat strains
Sprague Dawley
(outbred)Long Evans
(outbred)Wistar
(outbred)Lewis
(inbred)Why Rat Models?
Rats have been used to model human disease for over a century within a broad range of science fields including neurobiology, cardiology, immunology and toxicology.
Their size and physiological similarity to humans make them an ideal choice for many labs. For example, surgical manipulations can be performed on rats that are difficult or impossible with smaller rodents, and fewer animals are required to generate sufficient material for experiments.
Trusted by Leading Researchers
“The rat knock-in model from ingenious was reliable, precise, and accelerated our immunology research significantly.”
— Carla Rothlin, Professor and Director of Center of Immunology
Yale University
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View our comprehensive legacy documentation with in-depth specifications.
Rat Model Resources
Download our free guides to learn more about custom rat model generation.