ingenious Blog

The ingenious Blog

Press Release: Breakthrough CRISPR/Cas9 Rat Model Technology

RONKONKOMA, N.Y., October 17, 2017 ( – ingenious targeting laboratory is excited to announce the addition of custom gene-edited rat models via an exciting breakthrough technology. Our unique CRISPR/Cas9 rat technology utilizing spermatogonial stem cells streamlines the production of rat models with unparalleled speed and accuracy, establishing germline-confirmed rat lines 50

CRISPR-Cas9 Gene Edited Human Embryo Repair Study Challenged

Challenging the Effectiveness of CRISPR-Cas9 in Repairing Human Embryo Gene Mutations   CRISPR-Cas9 gene editing methods are used increasingly more often for the purpose of correcting gene mutations that can impair healthy gene function and physiological development. Recently, however, embryology and genetics experts have questioned last month’s report that allegedly

Build A Better Mouse Model

Build a Better Mouse Model, with 2A Peptide Strategies Researchers often ask us about ways to track a knockout or knockin allele in a new mouse model, or how to express multiple proteins in a single mouse model. Utilizing the 2A peptide is often an ideal solution. The 2A peptide

Eye Microbiome Trigger Immune Response in Mice Models

Study Proves a Resident Ocular Microbiome   “Bugs in your eyes may be a good thing.” New research is showing that immune responses that protect the eye from infection are due to microbes living on the surface of the eye. Research conducted at the National Eye Institute (NEI), part of

Fixing Off Target Effects of CRISPR/Cas9

Fixing Off Target Effects of CRISPR/Cas9 CRISPR’s simplicity and accessibility has given itself the oxygen to spread like wildfire through the research community, but so have it’s off target effects. Recently, scientists have used it in clinical trials for slowing or stopping the production of lung cancer cells, but due