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Our Services

About ingenious targeting laboratory

Since 1998, ingenious targeting laboratory has been generating custom mouse, rat, and rabbit models for researchers worldwide. From our facilities in Holbrook, New York, we have completed more than 2,500 gene targeting projects contributing to over 800 peer reviewed publications across every major therapeutic area.

2,500+
Projects Completed
800+
Publications
26+
Years Experience
100%
Success Rate

History of ingenious targeting laboratory

ingenious targeting laboratory's story began in the early 1990s. The founders worked as researchers in the same lab at Rockefeller University. During their time at Rockefeller, they developed custom atherosclerotic knockout mouse models for studying heart disease. In 1998, they founded ingenious targeting laboratory and still continue to work directly in the lab, oversee mouse model production, and also handle the operation and business side of things.

As ingenious targeting laboratory, we first settled in at the Long Island High Technology Incubator (LIHTI) at Stony Brook University, discussing and sharing ideas with other researchers and companies in that space. A little over 10 years later, we expanded and moved to a larger facility on Long Island with 20,000 square feet. We still work closely with Stony Brook's Division of Laboratory Animal Resources (DLAR) to house many of our mice.

From our small beginnings as one of the very first mouse gene targeting companies in the world, we've grown and streamlined our model generation process. Today ingenious uses both traditional and cutting edge technologies to design custom mouse lines for our clients globally.

Our Location

Holbrook, New York

Our corporate headquarters and laboratories are located in Holbrook, New York, USA. We are fortunate to be surrounded by, and enjoy relationships with, world class research institutions such as Stony Brook University, Cold Spring Harbor and Brookhaven National Laboratory.

In addition, being located near New York City places us at a global hub of travel, providing us with a gateway to our clients across the USA and the world. Our convenient location also gives us the opportunity to bring top talent to the ingenious team.

761-80 Coates Avenue
Holbrook, NY 11741

All Work Performed in the USA 🇺🇸

Research Partnerships

Stony Brook University

Division of Laboratory Animal Resources (DLAR)

Cold Spring Harbor Laboratory

World renowned research institution

Brookhaven National Laboratory

Leading scientific research center

Dedicated scientists are with you from start to finish

Drs. Jennifer Parla, Milen Kirilov, and Arielle Bryan are part of our team of scientific experts who work directly in the lab and oversee every aspect of your project.

Our Guarantee

As part of our commitment to you, we guarantee delivery of your germline confirmed F1 heterozygous mice. We achieve our guarantee by providing the following:

Best Quality Constructs

Best quality targeting vector constructs, ranging in sizes from plasmid to BAC.

Proprietary ES Cell Lines

Proprietary mouse ES cell lines that consistently and reliably transmit to germline.

FLP ES Cell Technology

Our own FLP ES cell technology for streamlined deletion of antibiotic selection cassette without extra steps.

With our guarantee, you can be confident in knowing that you will receive the mice you need at the cost you agreed to.

Why researchers choose ingenious targeting laboratory

Certainty

The model you design is the model we deliver.

Guaranteed Delivery

Assurance of your mouse model, not just your money back.

Value

Our proprietary technologies save time and money.

Trusted Precision

Exactly what you need, our experts make it happen.

Fast Timelines

Germline in less time than ever before.

Assured Quality

The quality you need, the value you seek.

"iTL generated our angiotensin II type 1a receptor conditional mouse. We found this company very responsive. The project started with discussions on possible construct designs. Following approval, a project manager sent monthly reports alerting us to project milestones. Our experience with iTL was so positive that we have generated more conditional mice with them."

— Debra Rateri, BS, University of Kentucky

Start your project today

Our scientific consultants are ready to discuss your research requirements and recommend the optimal approach for your program. Initial consultation is provided at no charge.

Frequently asked questions

We provide custom genetically engineered mouse, rat, and rabbit model generation, including knockout, knockin, conditional knockout, humanized models, and transgenic models. Additional services include colony management, cryopreservation, backcrossing, and preclinical services.

We have been generating custom mouse models since 1998, with over 26 years of experience and 2,500+ successful projects. Our models have been published in leading journals including Nature, Cell, Science, and Journal of Clinical Investigation, demonstrating consistent quality and scientific impact.

Contact us through our request quote form or schedule a consultation. Our scientific team provides complimentary consultation to discuss your research goals, recommend optimal targeting strategies, and develop a project proposal. We work with you throughout the project to ensure the model meets your research needs.

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