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Custom Animal Models

At ingenious targeting laboratory, every model we create is custom tailored for the specific needs of your research. Our advanced and versatile animal model types including conditional point mutants, and conditional knockouts incorporating reporter genes, can become the cornerstone of your research.  Contact us today to discuss the ideal custom model for your next project and beyond.


Together we choose the best design and approach for your new model.

Guaranteed Delivery. With our proprietary service ingenious CRISPR 100%, we produce the model you need with certainty. 

We provide confirmed germline transmitters and a complete screening strategy for your lab to use.



Benefits of Working with ingenious

Experience– 19 years of custom animal model generation.

Proven success– models used in hundreds of published studies.

Satisfaction– customers return again and again with new projects. 

Guaranteed delivery–  your animal model, not just your money back.

Personalized support– from before your project begins to after your models are delivered. 





How we work together with you at every stage of model production:

custom mouse models


Why Make a Humanized Mouse?

By Kristen Coughlin Humanized Mouse Models The mouse has been used for over 30 years as a model system for studying human disease.  Recently, “humanized” mice have grown in popularity because they are formidable models of the human being and therefore extremely useful for understanding the human condition.  What exactly is a humanized mouse? A

Brain Health And Iron Levels – A Delicate Balance

By Richard Row, Ph.D. Understanding Brain Health Decades of intense study have shown that the processes involved in neurodegeneration are inextricably linked to those required for the formation and maintenance of a healthy brain. Thousands of distinct molecular mechanisms must be exquisitely balanced to preserve a healthy, functioning organ through decades of life, and this

3 things I wish I knew before making my first knockin mouse model

My First Knockin Mouse Model Creating a new mouse model is a major step in any research program. Some things may have come to mind such as, “Can’t I finish this project using models that already exist?” or “Will I ever graduate if I undertake a knockin mouse model project?” If you have reached a

Cre-Lox Facts

6 Facts You May Not Know About Cre-Lox By Richard Row, PhD The basics of conditional knockout mice are familiar to any researcher who uses mouse models, even if this model type isn’t yet a part of your research. Using the Cre-lox system in an experiment seems simple: two lines are crossed, one with tissue-specific

“We are actively engaged in the production of a number of conditional mouse models with iTL. This collaboration has been simple on my end, just providing the gene accession numbers of each gene, and iTL recommending the strategies for each gene. The full range of mouse knockout services matches my needs well. I find iTL’s service uniquely useful for my situation of needing different models for my research in a quick and efficient manner.”

– Mehboob Hussain, MD

custom mouse models