Skip to main content
Comprehensive Support

Post Project Services

Beyond custom mouse model generation, ingenious targeting laboratory provides comprehensive support services to maintain, expand, and preserve your valuable mouse colonies. Since 1998, we have supported researchers with colony management, cryopreservation, rederivation, and breeding services that maximize research productivity while ensuring genetic integrity.

From colony maintenance through phenotypic characterization, our support services enable you to focus on your research while we manage the logistics.

2,500+
Projects Completed
800+
Publications
26+
Years Experience
100%
Success Rate

Colony Management Services

Maintaining a productive mouse colony requires consistent husbandry, accurate genotyping, and strategic breeding decisions.

Breeding Colony Maintenance

Documented pedigrees, organized mating schemes, and regular health monitoring to ensure colony productivity and genetic integrity.

Genotyping Services

PCR based assays to identify carriers, homozygotes, and compound mutants. ingenious targeting laboratory develops custom genotyping protocols for each targeted allele.

Cohort Development

Generate study ready animals on your timeline. We can expand from founders to experimental cohorts while you focus on research design and data analysis.

Strain Background Management

Backcrossing to congenic backgrounds and speed congenic services using SNP marker panels to accelerate background conversion.

Cryopreservation Services

Cryopreservation protects your mouse lines against colony loss while reducing ongoing maintenance costs.

Sperm Cryopreservation

The most cost effective archival solution. Frozen sperm from characterized males can regenerate your line through IVF when needed.

Embryo Cryopreservation

Freezes two cell stage embryos for rapid colony recovery. This approach preserves both maternal and paternal genetics in a single archive.

ES Cell Cryopreservation

Maintains targeted ES cell clones for future use, enabling generation of additional mice or derivative alleles without repeating the targeting process.

Archive and Recovery

Quality controlled storage with documented inventory and validated recovery procedures to regenerate colonies from frozen stocks.

Rederivation Services

Rederivation eliminates adventitious pathogens and establishes clean health status for mouse lines.

Embryo Transfer Rederivation

Uses IVF or natural mating to generate embryos that are transferred to pathogen free recipients, producing offspring with documented clean health status.

Health Status Upgrade

Enables transfer of lines between facilities with different health barriers or recovery of lines from compromised health status.

Quarantine and Testing

Provides documented health screening before integration into clean facilities.

Speed Expansion Breeding

Accelerate timeline from founders to experimental cohorts.

Superovulation Protocols

Increase embryo yield from valuable females, accelerating colony expansion.

IVF Recovery

Rapid regeneration of archived lines from cryopreserved sperm.

Strategic Breeding Schemes

Optimize mating configurations to achieve target genotypes efficiently.

Cohort Coordination

Delivers animals at specified ages and genotypes aligned with your experimental timeline.

Service Comparison

ServiceBest ForTimeline
Colony ManagementOngoing breeding supportContinuous
Sperm CryopreservationCost effective archival2 to 4 weeks
Embryo CryopreservationRapid recovery needed4 to 6 weeks
RederivationHealth status upgrade8 to 12 weeks
Speed ExpansionAccelerated cohort generationVariable
PhenotypingModel characterizationVariable

What Researchers Say

Our project manager did an outstanding job and has provided us with excellent customer service. Her availability to clarify issues has been nothing short of fantastic. I have recommended ingenious to others. Look forward for further collaboration on other projects.

Hamid M. Said, PhD, PharmD

University of California, Irvine

Start Your Project

Whether you need ongoing colony support, archival services, or complete project management, ingenious targeting laboratory's service team can design a support plan aligned with your research goals.

Frequently Asked Questions

ingenious targeting laboratory provides comprehensive support services including colony management (breeding colony maintenance, genotyping, cohort development, strain background management), cryopreservation (sperm, embryo, ES cell archival), rederivation (pathogen-free line establishment), and speed expansion breeding (rapid cohort generation).

Colony management services provide breeding colony maintenance with documented pedigrees, organized mating schemes, and regular health monitoring. Genotyping services identify carriers, homozygotes, and compound mutants. Cohort development generates study-ready animals on your timeline while you focus on research design.

Cryopreservation methods include sperm cryopreservation (most cost-effective archival solution), embryo cryopreservation (preserves both maternal and paternal genetics), and ES cell cryopreservation (maintains targeted ES cell clones for future use). Archive and recovery services include quality-controlled storage with validated recovery procedures.

Rederivation is needed when mouse lines become contaminated with pathogens, need to be moved to SPF facilities, or require health status upgrade for specific research protocols. Rederivation eliminates adventitious pathogens and establishes clean health status through embryo transfer or IVF into pathogen-free recipients.