"A better model is within reach."

About ingenious

Gene editing

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We’re the only mouse model company to perform all service steps in the USA.

Established in 1998, ingenious targeting laboratory (ingenious) is a leading global provider of custom genetically modified mouse, rat, and rabbit models. Our trusted gene editing service is built on nearly two decades’ worth of successful animal model creation for investigators, organizations, and companies in 44 states and 28 countries. We establish and maintain strong client relationships and support, and ensure the highest quality of our products. Our clients retain full intellectual property rights to their projects and benefit from full confidentiality.

ingenious stands as one of the very first mouse gene targeting companies. Our models have been published in hundreds of journals including Science, Nature, and Cell, making us one of the most validated and trusted production companies in the industry. Our research clients return time and again, and refer their friends and colleagues for the service provided by ingenious.

Dedicated scientists are with you from start to finish.


Accelerated the Research of Over 900 Laboratories


Over 20 Years of Experience


Over 1,900 Completed Projects

Trusted Precision: Exactly what you need, our experts make it happen.

Fast Timelines: Guaranteed germline in less time than ever before.

Assured Quality: The quality you need, the value you seek.

Our emphasis has always been on delivering the highest quality product by utilizing the best technologies.
A better model is within reach.

ingenious targeting laboratory Clients Map

Delivering models that have advanced the research of hundreds of laboratories worldwide, ingenious utilizes both embryonic stem (ES) cell and CRISPR/Cas9 based technologies. Some of the mouse models we create include: constitutive and conditional (loxP) knockout mouse models, knockin mouse models (point mutations, cDNAs, reporter genes, tags, etc), humanized mouse models, inducible/reversible gene expression mouse models, and targeted transgenic mouse models. Utilizing our proprietary technologies results in the production of sophisticated, next generation animal models that help advance our understanding of human disease.

Client Testimonials

I am very happy with iTL’s mouse knockout services. It was pleasant to collaborate with my project manager. She was very thorough and communicative, an excellent combination. I will certainly use iTL again when needed, and I’m happy to share my positive experience with colleagues.

John Creemers, PhD

John Creemers, PhD
Ku Leveun

We have worked with inGenious Targeting Laboratory, Inc. on a variety of conventional, conditional and knockin projects, and we are very impressed with how flexible their service was to our needs and expectations. We look forward to our continued success in generating different mouse models with iTL.

Iannis Aifantis, PhD

Iannis Aifantis, PhD
NYU Langone Medical Center


Our corporate headquarters and laboratories are located in Ronkonkoma, New York, U.S.A. We are fortunate to be surrounded by, and enjoy relationships with, world-class research institutions such as Stony Brook University, Cold Spring Harbor and Brookhaven National Laboratory. In addition, being located near New York City places us at a global hub of travel, providing us with a gateway to our clients across the U.S.A. and the world.