About ingenious

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About ingenious

Established in 1998, ingenious targeting laboratory is a leading global provider of custom genetically modified mouse models.  Our trusted gene editing service is built on nearly two decades’ worth of successful mouse model creation for investigators, organizations, and companies in 44 states and 25 countries.  We establish and maintain strong client relationships and support, and ensure the highest quality of our products.  Our clients retain full intellectual property rights to their projects and benefit from full confidentiality.

Over 1,800 completed projects

44 states and 25 countries

All projects produced in the U.S.A

As one of the very first mouse gene targeting companies, ingenious targeting laboratory (ingenious) has been providing custom genetically modified knockout and knockin models to researchers worldwide for nearly two decades. With over 1,800 projects completed and validation of our mouse model production capabilities published in hundreds of journal articles including in Science, Nature, and Cell, our research clients return time and again, and refer their friends and colleagues for the service provided by ingenious.


Our emphasis has always been on delivering the highest quality product by utilizing the best technologies.
A Better Model is Within Reach.

Delivering models that have advanced the research of hundreds of laboratories worldwide, ingenious utilizes both embryonic stem (ES) cell and CRISPR/Cas9 based technologies. Some of the mouse models we create include: constitutive and conditional (loxP) knockout mouse models, knockin mouse models (point mutations, cDNAs, reporter genes, tags, etc), humanized mouse models, inducible/reversible gene expression mouse models, and targeted transgenic mouse models. Utilizing our proprietary technologies results in the production of sophisticated, next generation mouse models and advancements in gene editing.

“I am very happy with iTL’s mouse knockout services. It was pleasant to collaborate with my project manager. She was very thorough and communicative, an excellent combination. I will certainly use iTL again when needed, and I’m happy to share my positive experience with colleagues.”

gene editing

John Creemers, PhD

“We have worked with inGenious Targeting Laboratory, Inc. on a variety of conventional, conditional and knockin projects, and we are very impressed with how flexible their service was to our needs and expectations. We look forward to our continued success in generating different mouse models with iTL.”

gene editing

Iannis Aifantis, PhD


Our corporate headquarters and laboratories are located in Ronkonkoma, New York, U.S.A. We are fortunate to be surrounded by, and enjoy relationships with, world-class research institutions such as Stony Brook University, Cold Spring Harbor and Brookhaven National Laboratory. In addition, being located near New York City places us at a global hub of travel, providing us with a gateway to our clients across the U.S.A. and the world.

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