Established in 1998, ingenious targeting laboratory (ingenious) is a leading global provider of custom genetically modified mouse, rat, and rabbit models. Our trusted gene editing service is built on nearly two decades’ worth of successful animal model creation for investigators, organizations, and companies in 44 states and 28 countries. We establish and maintain strong client relationships and support, and ensure the highest quality of our products. Our clients retain full intellectual property rights to their projects and benefit from full confidentiality.
ingenious stands as one of the very first mouse gene targeting companies. Our models have been published in hundreds of journals including Science, Nature, and Cell, making us one of the most validated and trusted production companies in the industry. Our research clients return time and again, and refer their friends and colleagues for the service provided by ingenious.
ingenious targeting laboratory’s story began in the early 1990s. The founders worked as researchers in the same lab at Rockefeller University. During their time at Rockefeller, they developed custom atherosclerotic knockout mouse models for studying heart disease. In 1998, they founded ingenious targeting laboratory and still continue to work directly in the lab, oversee mouse model production, and also handle the operation and business side of things.
As ingenious targeting laboratory, we first settled in at the Long Island High Technology Incubator (LIHTI) at Stony Brook University, discussing and sharing ideas with other researchers and companies in that space. A little over 10 years later, we expanded and moved to a larger facility on Long Island with 20,000 square feet. We still work closely with Stony Brook’s Division of Laboratory Animal Resources (DLAR) to house many of our mice.
From our small beginnings as one of the very first mouse gene targeting companies in the world, we’ve grown and streamlined our model generation process. Today ingenious uses both traditional and cutting-edge technologies to design custom mouse lines for our clients globally.
Accelerated the Research of Over 900 Laboratories
Over 20 Years of Experience
Over 2,000 Completed Projects
Trusted Precision: Exactly what you need, our experts make it happen. Fast Timelines: Guaranteed germline in less time than ever before. Assured Quality: The quality you need, the value you seek.
Trusted Precision: Exactly what you need, our experts make it happen.
Fast Timelines: Guaranteed germline in less time than ever before.
Assured Quality: The quality you need, the value you seek.
Delivering models that have advanced the research of hundreds of laboratories worldwide, ingenious utilizes both embryonic stem (ES) cell and CRISPR/Cas9 based technologies. Some of the mouse models we create include: constitutive and conditional (loxP) knockout mouse models, knockin mouse models (point mutations, cDNAs, reporter genes, tags, etc), humanized mouse models, inducible/reversible gene expression mouse models, and targeted transgenic mouse models. Utilizing our proprietary technologies results in the production of sophisticated, next generation animal models that help advance our understanding of human disease.
I am very happy with iTL’s mouse knockout services. It was pleasant to collaborate with my project manager. She was very thorough and communicative, an excellent combination. I will certainly use iTL again when needed, and I’m happy to share my positive experience with colleagues.
John Creemers, PhD
We have worked with inGenious Targeting Laboratory, Inc. on a variety of conventional, conditional and knockin projects, and we are very impressed with how flexible their service was to our needs and expectations. We look forward to our continued success in generating different mouse models with iTL.
Iannis Aifantis, PhD
NYU Langone Medical Center
Our corporate headquarters and laboratories are located in Ronkonkoma, New York, U.S.A. We are fortunate to be surrounded by, and enjoy relationships with, world-class research institutions such as Stony Brook University, Cold Spring Harbor and Brookhaven National Laboratory. In addition, being located near New York City places us at a global hub of travel, providing us with a gateway to our clients across the U.S.A. and the world. Our convenient location also gives us the opportunity to bring top talent to the ingenious team.