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Full Service Model Creation

A full-service project from ingenious will apply the power of the CRISPR/Cas9 system to your project, with assured results. Our scientists are backed by almost 20 years of experience and will create custom targeting strategies for your gene of interest.  Together we carefully evaluate your needs and research goals and translate them into personalized project parameters for your particular mouse model. Before a project is initiated, the gene of interest is thoroughly evaluated at no extra cost. Our track record allows us to guarantee delivery of the mice you need, giving us the confidence to call our proprietary service- ingenious CRISPR 100%.  

The power of CRISPR/Cas9, the certainty you need.

Our proprietary process allows us to produce the models you need with 100% certainty.  With predictable timelines, a price that fits your budget, and our promise to you – Guaranteed Delivery of your mouse model – ingenious will succeed for you where others have failed.

ingenious CRISPR 100% utilizes a proprietary, mouse-specific process characterized by optimized, alternative production steps which are run simultaneously. Utilizing a broad, parallel workflow overcomes many of the disadvantages typical for standard CRISPR genome editing which relies on interdependent sequential as well as repetitive procedures. Our unique, integrative production approach enables significantly improved editing outcomes as it applies alternative paths towards the same genomic target.

The Advantages of Rat Models

By Kristen Coughlin The rat as a model system Rats were the first mammalian species specifically domesticated to be used in the laboratory. Two centuries ago, the brown rat Rattus norvegicus was used by scientists to understand human physiology and medicine, concentrating on the effects of food and oxygen deprivation. Rats have since been used
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Recent Client Publications!

Congratulations to our Clients Congratulations to our Clients Dr. Douglas Gould from UCSF School of Medicine, Dr. Ichizo Nishino from National Institute of Neuroscience, Japan, & Dr. Jian-xing Ma from University of Oklahoma Health Sciences Center. Their research and publications included the use of conditional knockout models, and point mutation knockin mouse models from ingenious. They now are among the hundreds
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Gene Therapy and Usher Syndrome

The Promising Results in Using Gene Therapy to Treat Usher Syndrome Patients Gene therapy has advanced considerably in recent years, due particularly to mutant mouse models genetically modified to mimic the effects of health problems like deafness and help test effective treatments. Various studies published this February in Nature Biotechnology showed the progress researchers have
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“I worked with ITL on the generation of a conditional knockout mouse strain for a complex gene. I have been very impressed by their flexibility and their efficiency in completing each steps with no delays. I’m glad to share this experience and highly recommend ITL’s services.”

-Frédéric Marmigère, PhD