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Ace2 Conditional Knockout, Knockin, Knockout mouse models
Browse 4 Ace2 mouse models including conditional knockout, knockin, knockout variants from ingenious targeting laboratory. Available as Ace2 conditional knockout mouse, Ace2 knockin mouse, Ace2 knockout mouse, Ace2 xenograft-applicable mouse. Contact us for availability and fast turnaround.
Available Ace2 catalog models
4 Ace2 lines with QC documentation and technical support. Ace2 floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.
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Ace2-Flox
CKOCKO
These strains carry loxP sites flanking exon 6-8 of Ace2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ace2 gene.
Sperm CryopreservedCKO 233149 - Order
Ace2-2A-CreERT2
KICre/Dre Toolbox
A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ace2 gene stop codon site. Ace2 encodes angiotensin I converting enzyme 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful for studying lung injury and kidney disease caused by SARS coronavirus infection.
Sperm CryopreservedKI 200187 - Order
Ace2-KO
KOKO
exon 3-7 of Ace2 gene was deleted to generate Ace2 knockout mice.
Sperm CryopreservedKO 190906 - Order
Ace2-Flox/Vil1-CreERT2
XAOther
The Ace2-Flox (CKO 233149) was crossed with Vil1-CreERT2(KI 225020) to generate Ace2-Flox/Vil1-CreERT2 mice.
In DevelopmentXA 263478
Looking for a Ace2 mouse model?
We have 4 Ace2 models available — including Conditional Knockout, Knockin, Knockout types. Contact us today for current availability and our fastest turnaround options. All models come with full QC documentation and technical support.
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Order catalog modelAbout Ace2 Mouse Model Types
A Ace2 knockout mouse has the Ace2 gene permanently inactivated, enabling loss of function studies. A Ace2 conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Ace2, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints. Ace2 knockin models carry a precisely inserted sequence at the Ace2 locus, useful for reporter, tag, or humanization studies.
Modifications available
Jump to catalog backed pages for Ace2 organized by modification type. Each URL is indexable and matches common search patterns.
Breed this line with ingenious targeting laboratory
Send the Ace2 line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.