Ache Conditional Knockout, Knockout mouse models

Available Ache catalog models

2 Ache lines with QC documentation and technical support. Ache floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.

• Ache-Flox

  CKO

  CKO

  These mice carry loxP sites flanking exon 2-3 of Ache gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ache gene.

  Embryo CryopreservedCKO 200270
  Order

• Ache-KO

  KO

  KO

  Exon 2-3 of Ache gene was deleted to generate Ache knockout mice.

  F0 Embryo CryopreservedKO 225114
  Order

About Ache Mouse Model Types

A Ache knockout mouse has the Ache gene permanently inactivated, enabling loss of function studies. A Ache conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Ache, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints.

Modifications available

Jump to catalog backed pages for Ache organized by modification type. Each URL is indexable and matches common search patterns.

Breed this line with ingenious targeting laboratory

Send the Ache line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.