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Alpl Conditional Knockout, Humanized, Knockout mouse models
Browse 3 Alpl mouse models including conditional knockout, humanized, knockout variants from ingenious targeting laboratory. Available as Alpl conditional knockout mouse, Alpl humanized mouse, Alpl knockout mouse. Contact us for availability and fast turnaround.
Available Alpl catalog models
3 Alpl lines with QC documentation and technical support. Alpl floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout. Alpl humanized models carry the human gene sequence for translational research.
- Order
Alpl-Flox
CKOCKO
These mice carry loxP sites flanking exon 3-4 of Alpl gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Alpl gene.
Sperm CryopreservedCKO 226290 - Order
hALPL
HUTarget-Humanized
The endogenous mouse Alpl gene was replaced by human ALPL gene.
In DevelopmentHU 260005 - Order
Alpl-KO
KOKO, Disease Model
This Alpl knockout mouse model was obtained by knocking out the exon 3-4 region of the Alpl gene.
Embryo CryopreservedKO 18058
Looking for a Alpl mouse model?
We have 3 Alpl models available — including Conditional Knockout, Humanized, Knockout types. Contact us today for current availability and our fastest turnaround options. All models come with full QC documentation and technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog modelAbout Alpl Mouse Model Types
A Alpl knockout mouse has the Alpl gene permanently inactivated, enabling loss of function studies. A Alpl conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Alpl, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints. A Alpl humanized mouse replaces the mouse Alpl gene with the human ortholog for translational research and drug development.
Modifications available
Jump to catalog backed pages for Alpl organized by modification type. Each URL is indexable and matches common search patterns.
Alpl mouse model FAQ
What Alpl Conditional Knockout mouse models are available?
When Alpl Conditional Knockout lines are in catalog, we ship from inventory. If your configuration is not listed, we design the allele to order. Common paths include conditional knockout, constitutive knockout, humanized, knockin, and transgenic options, with documented germline transmission and United States QC.
Is Alpl knockout embryonic lethal in mice?
It depends on background and allele design. Some Alpl germline knockouts are viable. Others need conditional alleles or mixed backgrounds. We review publications and our own experience, then recommend floxed versus null before you commit.
Which Cre driver is best for experiments?
Driver choice depends on onset timing, recombination efficiency, and known leak. We map your organ and cell type to a short list of proven Cre lines, then talk through reporter crosses and controls. We favor drivers with strong community validation for your tissue.
Do you ship live Alpl animals?
When catalog lines are live, we ship with health certificates and QC documentation. If your exact combo is not listed, we quote a generation project with cryo or live dispatch depending on cohort timing and geography.
How do I request a quote for Alpl?
Use the catalog inquire buttons or the request quote form. Include your allele goal, Cre plan if any, strain background, and cohort size. A PhD led team responds with pricing, milestones, and the fastest path to experimental animals.
Breed this line with ingenious targeting laboratory
Send the Alpl line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.