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Aplnr Conditional Knockout, Humanized, Knockin mouse models
Browse 4 Aplnr mouse models including conditional knockout, humanized, knockin variants — in stock and ready to ship from ingenious targeting laboratory. Available as Aplnr conditional knockout mouse, Aplnr humanized mouse, Aplnr knockin mouse, Aplnr knockout mouse. Request a quote within 24 hours.
Available Aplnr catalog models
4 Aplnr lines with QC documentation and technical support. Aplnr floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout. Aplnr humanized models carry the human gene sequence for translational research.
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Aplnr-Flox
CKOCKO
These strains carry loxP sites flanking exon 1 of Aplnr gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aplnr gene.
Sperm CryopreservedCKO 233990 - Order
hAPLNR
HUTarget-Humanized
The endogenous mouse Aplnr gene was replaced by human APLNR gene.
LiveHU 242249 - Order
Aplnr-2A-DreERT2
KICre/Dre Toolbox
A 2A-DreERT2-SV40polyA coexpression cassette is inserted befor the stop codon of mouse Aplnr gene via homologous recombination to establish a tamoxifen inducible Aplnr-DreERT2 tool stain. This strain can be used to knockout target gene in Aplnr+ cells after tamoxifen treatment when crossed with mice which carry rox sites flanking target gene.
Embryo CryopreservedKI 00132 - Order
Aplnr-KO
KOKO
Exon 1 of Aplnr gene was deleted to generate Aplnr knockout mice
Embryo CryopreservedKO 210239
Looking for a Aplnr mouse model?
We have 4 Aplnr models in stock — including Conditional Knockout, Humanized, Knockin types. In stock and ready to ship this week. All models come with full QC documentation, health certificates, and dedicated technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog modelAbout Aplnr Mouse Model Types
A Aplnr knockout mouse has the Aplnr gene permanently inactivated, enabling loss of function studies. A Aplnr conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Aplnr, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints. Aplnr knockin models carry a precisely inserted sequence at the Aplnr locus, useful for reporter, tag, or humanization studies. A Aplnr humanized mouse replaces the mouse Aplnr gene with the human ortholog for translational research and drug development.
Modifications available
Jump to catalog backed pages for Aplnr organized by modification type. Each URL is indexable and matches common search patterns.
Aplnr mouse model FAQ
What Aplnr Conditional Knockout mouse models are available?
When Aplnr Conditional Knockout lines are in catalog, we ship from inventory. If your configuration is not listed, we design the allele to order. Common paths include conditional knockout, constitutive knockout, humanized, knockin, and transgenic options, with documented germline transmission and United States QC.
Is Aplnr knockout embryonic lethal in mice?
It depends on background and allele design. Some Aplnr germline knockouts are viable. Others need conditional alleles or mixed backgrounds. We review publications and our own experience, then recommend floxed versus null before you commit.
Which Cre driver is best for experiments?
Driver choice depends on onset timing, recombination efficiency, and known leak. We map your organ and cell type to a short list of proven Cre lines, then talk through reporter crosses and controls. We favor drivers with strong community validation for your tissue.
Do you ship live Aplnr animals?
When catalog lines are live, we ship with health certificates and QC documentation. If your exact combo is not listed, we quote a generation project with cryo or live dispatch depending on cohort timing and geography.
How do I request a quote for Aplnr?
Use the catalog inquire buttons or the request quote form. Include your allele goal, Cre plan if any, strain background, and cohort size. A PhD led team responds with pricing, milestones, and the fastest path to experimental animals.
Breed this line with ingenious targeting laboratory
Send the Aplnr line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.