Avp Conditional Knockout, Knockin, Knockout mouse models

Available Avp catalog models

3 Avp lines with QC documentation and technical support. Avp floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.

• Avp-Flox

  CKO

  CKO

  These strains carry loxP sites flanking exon 2-3 of Avp gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Avp gene.

  Sperm CryopreservedCKO 240055
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• Avp-IRES-Cre

  KI

  Cre/Dre Toolbox

  A IRES2-Cre-WPRE-polyA expression cassette was knocked into the Avp gene stop codon site. Avp encodes arginine vasopressin. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying hypertension.

  Sperm CryopreservedKI 200142
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• Avp-KO

  KO

  KO

  The exon 2-3 of Avp gene was deleted to generate Avp knockout mouse.

  Sperm CryopreservedKO 251022
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About Avp Mouse Model Types

A Avp knockout mouse has the Avp gene permanently inactivated, enabling loss of function studies. A Avp conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Avp, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints. Avp knockin models carry a precisely inserted sequence at the Avp locus, useful for reporter, tag, or humanization studies.

Modifications available

Jump to catalog backed pages for Avp organized by modification type. Each URL is indexable and matches common search patterns.

Related Gene Targets

Breed this line with ingenious targeting laboratory

Send the Avp line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.