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B2m Conditional Knockout, Humanized, Immunodeficient mouse models
Browse 4 B2m mouse models including conditional knockout, humanized, immunodeficient variants — in stock and ready to ship from ingenious targeting laboratory. Available as B2m conditional knockout mouse, B2m humanized mouse, B2m immunodeficient mouse, B2m knockout mouse. Request a quote within 24 hours.
Available B2m catalog models
4 B2m lines with QC documentation and technical support. B2m floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout. B2m humanized models carry the human gene sequence for translational research.
- Order
B2m-Flox
CKOCKO
These mice carry loxP sites flanking exon 2-3 of B2m gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of B2m gene.
LiveCKO 2113502 - Order
hB2M
HUTarget-Humanized
The endogenous mouse B2m gene was replaced by human B2M gene.
Sperm CryopreservedHU 230007 - Order
B2m-KO(M-NSG)
NSGKO, Immunodeficient
This B2m knockout mouse model was obtained by knocking out the exon 2-3 region of mouse B2m gene on the background of NMG mouse.
LiveNSG 002 - Order
B2m-KO
KOKO, Immunodeficient
Exon2-3 of B2m gene were deleted to generate Ifngr1 knockout mice.
LiveKO 18021
Looking for a B2m mouse model?
We have 4 B2m models in stock — including Conditional Knockout, Humanized, Immunodeficient types. In stock and ready to ship this week. All models come with full QC documentation, health certificates, and dedicated technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog modelAbout B2m Mouse Model Types
A B2m knockout mouse has the B2m gene permanently inactivated, enabling loss of function studies. A B2m conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of B2m, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints. A B2m humanized mouse replaces the mouse B2m gene with the human ortholog for translational research and drug development.
Modifications available
Jump to catalog backed pages for B2m organized by modification type. Each URL is indexable and matches common search patterns.
B2m mouse model FAQ
What B2m Conditional Knockout mouse models are available?
When B2m Conditional Knockout lines are in catalog, we ship from inventory. If your configuration is not listed, we design the allele to order. Common paths include conditional knockout, constitutive knockout, humanized, knockin, and transgenic options, with documented germline transmission and United States QC.
Is B2m knockout embryonic lethal in mice?
It depends on background and allele design. Some B2m germline knockouts are viable. Others need conditional alleles or mixed backgrounds. We review publications and our own experience, then recommend floxed versus null before you commit.
Which Cre driver is best for experiments?
Driver choice depends on onset timing, recombination efficiency, and known leak. We map your organ and cell type to a short list of proven Cre lines, then talk through reporter crosses and controls. We favor drivers with strong community validation for your tissue.
Do you ship live B2m animals?
When catalog lines are live, we ship with health certificates and QC documentation. If your exact combo is not listed, we quote a generation project with cryo or live dispatch depending on cohort timing and geography.
How do I request a quote for B2m?
Use the catalog inquire buttons or the request quote form. Include your allele goal, Cre plan if any, strain background, and cohort size. A PhD led team responds with pricing, milestones, and the fastest path to experimental animals.
Breed this line with ingenious targeting laboratory
Send the B2m line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.