Fap Conditional Knockout, Knockout, Xenograft-Applicable mouse models

Available Fap catalog models

4 Fap lines with QC documentation and technical support. Fap floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.

• Fap-Flox

  CKO

  CKO

  These strains carry loxP sites flanking exon 3-6 of Fap gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Fap gene.

  Sperm CryopreservedCKO 231298
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• Fap-KO

  KO

  KO

  This Fap knockout mouse model was generated by knocking out the exon 4 region of the Fap .

  Embryo CryopreservedKO 190079
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• Fap-KO(2)

  KO

  KO

  The exon 3-6 of Fap gene was deleted to generate Fap knockout mouse.

  Sperm CryopreservedKO 251305
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• Fap-Flox/Pax7-IRES-CreERT2

  XA

  CKO, Cre/Dre Toolbox

  The Fap-Flox (CKO 231298) was crossed with Pax7-IRES-CreERT2(KI 200099) to generate Fap-Flox/Pax7-IRES-CreERT2 mice.

  In DevelopmentXA 251979
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About Fap Mouse Model Types

A Fap knockout mouse has the Fap gene permanently inactivated, enabling loss of function studies. A Fap conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Fap, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints.

Modifications available

Jump to catalog backed pages for Fap organized by modification type. Each URL is indexable and matches common search patterns.

Breed this line with ingenious targeting laboratory

Send the Fap line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.