Iapp Conditional Knockout, Knockout mouse models

Available Iapp catalog models

3 Iapp lines with QC documentation and technical support. Iapp floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.

• Iapp-Flox

  CKO

  CKO

  These strains carry loxP sites flanking exon 1-2 of Iapp gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Iapp gene.

  Sperm CryopreservedCKO 232190
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• Iapp-KO

  KO

  KO

  Exon 3 of Iapp gene was deleted to generate Iapp knockout mice.

  Embryo CryopreservedKO 190664
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• Iapp-KO(2)

  KO

  KO

  The exon 1-2 of Iapp gene was deleted to generate Iapp knockout mouse.

  Sperm CryopreservedKO 251268
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About Iapp Mouse Model Types

A Iapp knockout mouse has the Iapp gene permanently inactivated, enabling loss of function studies. A Iapp conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Iapp, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints.

Modifications available

Jump to catalog backed pages for Iapp organized by modification type. Each URL is indexable and matches common search patterns.

Breed this line with ingenious targeting laboratory

Send the Iapp line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.