Mt1 Conditional Knockout, Knockout mouse models

Available Mt1 catalog models

4 Mt1 lines with QC documentation and technical support. Mt1 floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.

• Mt1-Flox(2)

  CKO

  CKO

  These mice carry loxP sites flanking exon 2-3 of Mt1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Mt1 gene.

  Sperm CryopreservedCKO 263663
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• Mt1-Flox/Mt2-Flox

  CKO

  CKO

  The MT1-FLOX model was constructed based on Mt2-Flox (CKO 226357) by inserting loxP sites on both sides of exon 2-3 of the Mt1 gene respectively. This flox mouse can be mated with tissue-specific Cre tool mice to obtain mouse models with the Mt1 gene knocked out in specific cell types or tissues.

  LiveCKO 252576
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• Mt1-Flox

  CKO

  CKO

  These strains carry loxP sites flanking exon 1-2 of Mt1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Mt1 gene.

  Sperm CryopreservedCKO 242445
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• Mt1-KO

  KO

  KO

  Exon2-3 of Mt1 gene were deleted to generate Mt1 knockout mice.

  Embryo CryopreservedKO 00161
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About Mt1 Mouse Model Types

A Mt1 knockout mouse has the Mt1 gene permanently inactivated, enabling loss of function studies. A Mt1 conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Mt1, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints.

Modifications available

Jump to catalog backed pages for Mt1 organized by modification type. Each URL is indexable and matches common search patterns.

Breed this line with ingenious targeting laboratory

Send the Mt1 line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.