Myf5 Conditional Knockout, Knockin, Knockout mouse models

Available Myf5 catalog models

3 Myf5 lines with QC documentation and technical support. Myf5 floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.

• Myf5-Flox

  CKO

  CKO

  These strains carry loxP sites flanking exon 1 of Myf5 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Myf5 gene.

  Sperm CryopreservedCKO 241436
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• Myf5-Cre

  KI

  Cre/Dre Toolbox

  A Cre-WPRE-polyA expression cassette was knocked into the Myf5 gene start codon site. Myogenic factor 5 (Myf5) belongs to the MRF family transcription factors that regulate myogenesis. It is expressed in the skeletal muscle and satellite cells. Severe loss of skeletal muscle following ablation of Myf5-expressing progenitors. This strain is useful in studying the differentiation of skeletal muscle.

  Sperm CryopreservedKI 200147
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• Myf5-KO

  KO

  KO

  The exon 1 of Myf5 gene was deleted to generate Myf5 knockout mouse.

  Sperm CryopreservedKO 251146
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About Myf5 Mouse Model Types

A Myf5 knockout mouse has the Myf5 gene permanently inactivated, enabling loss of function studies. A Myf5 conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Myf5, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints. Myf5 knockin models carry a precisely inserted sequence at the Myf5 locus, useful for reporter, tag, or humanization studies.

Modifications available

Jump to catalog backed pages for Myf5 organized by modification type. Each URL is indexable and matches common search patterns.

Related Gene Targets

Breed this line with ingenious targeting laboratory

Send the Myf5 line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.