Npr1 Conditional Knockout, Knockin, Knockout mouse models

Available Npr1 catalog models

4 Npr1 lines with QC documentation and technical support. Npr1 floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.

• Npr1-Flox(2)

  CKO

  CKO

  These mice carry loxP sites flanking exon 2-5 of Npr1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Npr1 gene.

  Sperm CryopreservedCKO 2100596
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• Npr1-LSL-2A-DTR-2A-tdTomato

  KI

  Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent)

  loxp-stop-loxp-P2A-DTR-T2A-tdTomato expression cassette was knocked into the Npr1 gene stop codon site.

  Sperm CryopreservedKI 220051
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• Npr1-KO(2)

  KO

  KO

  The exon 2-5 of Npr1 gene was deleted to generate Npr1 knockout mice.

  Sperm CryopreservedKO 230262
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• Npr1-KO

  KO

  KO

  Exon 2 of Npr1 gene was deleted to generate Npr1 knockout mice

  Embryo CryopreservedKO 210213
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About Npr1 Mouse Model Types

A Npr1 knockout mouse has the Npr1 gene permanently inactivated, enabling loss of function studies. A Npr1 conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Npr1, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints. Npr1 knockin models carry a precisely inserted sequence at the Npr1 locus, useful for reporter, tag, or humanization studies.

Modifications available

Jump to catalog backed pages for Npr1 organized by modification type. Each URL is indexable and matches common search patterns.

Related Gene Targets

Breed this line with ingenious targeting laboratory

Send the Npr1 line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.