Robo4 Conditional Knockout, Knockin, Knockout mouse models

Available Robo4 catalog models

4 Robo4 lines with QC documentation and technical support. Robo4 floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.

• Robo4-Flox

  CKO

  CKO

  These strains carry loxP sites flanking exon 5-7 of Robo4 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Robo4 gene.

  Sperm CryopreservedCKO 231336
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• Robo4-2A-CreERT2

  KI

  Cre/Dre Toolbox

  The 2A-CreERT2-WPRE-pA expression cassette was knocked into the Robo4 gene stop codon site.

  Sperm CryopreservedKI 252446
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• Robo4-KO(2)

  KO

  KO

  The exon 5-7 of Robo4 gene was deleted to generate Robo4 knockout mouse.

  Sperm CryopreservedKO 240225
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• Robo4-KO

  KO

  KO

  Exon 3 of Robo4 gene was deleted to generate Robo4 knockout mice.

  Embryo CryopreservedKO 200457
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About Robo4 Mouse Model Types

A Robo4 knockout mouse has the Robo4 gene permanently inactivated, enabling loss of function studies. A Robo4 conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Robo4, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints. Robo4 knockin models carry a precisely inserted sequence at the Robo4 locus, useful for reporter, tag, or humanization studies.

Modifications available

Jump to catalog backed pages for Robo4 organized by modification type. Each URL is indexable and matches common search patterns.

Related Gene Targets

Breed this line with ingenious targeting laboratory

Send the Robo4 line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.