Tph1 Conditional Knockout, Knockin, Knockout mouse models

Available Tph1 catalog models

8 Tph1 lines with QC documentation and technical support. Tph1 floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.

• Tph1-Flox(2)

  CKO

  CKO

  These mice carry loxP sites flanking exon 3 of Tph1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Tph1 gene.While Tph1-Flox(Stock No.CKO 200257）mice carrying the loxP sites flanking exon 4 of Tph1 gene.

  Sperm CryopreservedCKO 210038
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• Tph1-Flox

  CKO

  CKO

  These mice carry loxP sites flanking exon 4 of Tph1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Tph1 gene.While Tph1-Flox(2)(Stock No.CKO 210038）mice carrying the loxP sites flanking exon 3 of Tph1 gene.

  Embryo CryopreservedCKO 200257
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• Tph1-2A-mCherry

  KI

  Fluorescent Model

  2A-mCherry expression cassette was knocked into the Tph1 gene stop codon site.

  Sperm CryopreservedKI 220182
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• Tph1-2A-CreERT2

  KI

  Cre/Dre Toolbox

  The T2A-CreERT2-pA expression cassette was knocked into the Tph1 gene stop codon site.

  LiveKI 234904
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• Tph1-R251X

  KI

  Point Mutation

  These strains carry a R251X mutation of Tph1 gene.

  Sperm CryopreservedKI 232088
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• Tph1-KO(2)

  KO

  KO

  The exon4 of Tph1 gene was deleted to generate Tph1 knockout mouse.

  Sperm CryopreservedKO 231220
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• Tph1-KO

  KO

  KO

  Exon 3 of Tph1 gene was deleted to generate Tph1 knockout mice.

  Sperm CryopreservedKO 200774
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• Tph1-Flox(2)/Tph2-Flox

  XA

  CKO, Cre/Dre Toolbox

  The Tph1-Flox(2) (CKO 210038) was crossed with Tph2-Flox(CKO 253329) to generate Tph1-Flox(2)/Tph2-Flox mice.

  LiveXA 261781
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About Tph1 Mouse Model Types

A Tph1 knockout mouse has the Tph1 gene permanently inactivated, enabling loss of function studies. A Tph1 conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Tph1, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints. Tph1 knockin models carry a precisely inserted sequence at the Tph1 locus, useful for reporter, tag, or humanization studies.

Modifications available

Jump to catalog backed pages for Tph1 organized by modification type. Each URL is indexable and matches common search patterns.

Related Gene Targets

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