Ace Reporter Mouse
Since 1998, ingenious targeting laboratory has delivered 2,800+ projects with 100% germline transmission guarantee and 800+ peer reviewed publications.
Ace is a common request for reporter mouse models. ingenious targeting laboratory designs and delivers the line to your study specification with documented milestones.
Get a Quote in 24 HoursWhat Ace Reporter mouse models are available?
ingenious targeting laboratory designs and generates Ace reporter mouse models to your specification. Quotes return in about 24 hours with documented germline transmission and strict United States QC guidelines.
Scientific design
Ace is a well studied locus in mouse genetics. Allele design follows your phenotype goals and what the published landscape already shows for this gene.
3 existing alleles are indexed for Ace, including 1 conditional, including 2 knockout. Where the published set lacks the modification you need, ingenious targeting laboratory builds that allele with documented germline transmission.
Reporter alleles fuse a detectable marker to endogenous regulation so expression mirrors the native locus. Pre germline characterization confirms signal location before germline transmission.
Quotes return in about 24 hours with milestones, pricing, and options for cryo or live dispatch.
Reporter options for Ace
Ace GFP reporter
Green fluorescent protein fused to Ace regulatory elements reports native expression. ingenious targeting laboratory engineers the knockin and confirms pattern before germline transmission.
Ace YFP reporter
Yellow fluorescent protein fused to Ace regulatory elements reports native expression. ingenious targeting laboratory engineers the knockin and confirms pattern before germline transmission.
Ace RFP reporter
Red fluorescent protein fused to Ace regulatory elements reports native expression. ingenious targeting laboratory engineers the knockin and confirms pattern before germline transmission.
Ace mCherry reporter
Monomeric Cherry fluorescent protein fused to Ace regulatory elements reports native expression. ingenious targeting laboratory engineers the knockin and confirms pattern before germline transmission.
Ace tdTomato reporter
Tandem dimer Tomato fused to Ace regulatory elements reports native expression. ingenious targeting laboratory engineers the knockin and confirms pattern before germline transmission.
Ace lacZ reporter
Beta galactosidase reporter fused to Ace regulatory elements reports native expression. ingenious targeting laboratory engineers the knockin and confirms pattern before germline transmission.
Ace Luciferase reporter
Bioluminescent reporter fused to Ace regulatory elements reports native expression. ingenious targeting laboratory engineers the knockin and confirms pattern before germline transmission.
What researchers say
“ingenious targeting laboratory delivered exactly the floxed allele we designed, with clear milestones and germline confirmed founders.”
“The team translated our humanization requirements into a knockin strategy we could breed and phenotype on schedule.”
“Clear communication on allele design and germline transmission made our conditional knockout program straightforward to execute.”
Selected publications
- Neuroprotection From Intracerebral Hemorrhage Following Pharmacological Inhibition of GSK3β Depends on HFE Gene Status
- Microglia alter sex-specific cerebellar myelination following placental hormone loss
- Lysosomal NKG7 restrains mTORC1 activity to promote CD8+ T cell durability and tumor control
- PD-1 prelimits both the cytotoxic and exhaustion potential in thymic CD8+ T cells and impacts the maintenance of peripheral tumor immunity
- 12-Lipoxygenase inhibition delays onset of autoimmune diabetes in human gene replacement mice
FAQ
What Ace Reporter mouse models are available?
When Ace Reporter lines are in catalog, we ship from inventory. If your configuration is not listed, we design the allele to order. Common paths include conditional knockout, constitutive knockout, humanized, knockin, and transgenic options, with documented germline transmission and United States QC.
Is Ace knockout embryonic lethal in mice?
It depends on background and allele design. Some Ace germline knockouts are viable. Others need conditional alleles or mixed backgrounds. We review publications and our own experience, then recommend floxed versus null before you commit.
Which Cre driver is best for experiments?
Driver choice depends on onset timing, recombination efficiency, and known leak. We map your organ and cell type to a short list of proven Cre lines, then talk through reporter crosses and controls. We favor drivers with strong community validation for your tissue.
Do you ship live Ace animals?
When catalog lines are live, we ship with health certificates and QC documentation. If your exact combo is not listed, we quote a generation project with cryo or live dispatch depending on cohort timing and geography.
How do I request a quote for Ace?
Use the catalog inquire buttons or the request quote form. Include your allele goal, Cre plan if any, strain background, and cohort size. A PhD led team responds with pricing, milestones, and the fastest path to experimental animals.