READY TO SHIP!
EMBRYO
Hr Immunodeficient mouse models
These lines trade intact immunity for experimental access when the study design demands it.
What Hr Immunodeficient mouse models are available?
ingenious targeting laboratory offers 1 distinct Hr immunodeficient catalog mouse model. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
Catalog table
| Model | Type | Category | Availability | Catalog # | Action |
|---|---|---|---|---|---|
| Hr-KO(M-NSG) | NSG | KO, Immunodeficient | EMBRYO | NSG 021 | Inquire |
| exon 2 of Hr gene was deleted to generate Hr knockout mice. | |||||
Why this approach
We help teams pick alleles that match the experimental question, the organ system, and future breeding plans. For your target tissue centric work, Cre specificity, flox placement, and baseline controls matter as much as the gene edit itself.
Pricing and quotes
The Hr Immunodeficient lines listed above are catalog models. Send us the catalog number and our team confirms current availability, pricing, and whether the line ships cryopreserved or live.
If your study needs a Hr allele configuration that is not listed above, our scientific team designs and generates it. Model generation quotes return in about twenty four hours with project milestones and pricing.
FAQ
What Hr Immunodeficient mouse models are available?
When Hr Immunodeficient lines are in catalog, we ship from inventory. If your configuration is not listed, we design the allele to order. Common paths include conditional knockout, constitutive knockout, humanized, knockin, and transgenic options, with documented germline transmission and United States QC.
Is Hr knockout embryonic lethal in mice?
It depends on background and allele design. Some Hr germline knockouts are viable. Others need conditional alleles or mixed backgrounds. We review publications and our own experience, then recommend floxed versus null before you commit.
Which Cre driver is best for experiments?
Driver choice depends on onset timing, recombination efficiency, and known leak. We map your organ and cell type to a short list of proven Cre lines, then talk through reporter crosses and controls. We favor drivers with strong community validation for your tissue.
Do you ship live Hr animals?
When catalog lines are live, we ship with health certificates and QC documentation. If your exact combo is not listed, we quote a generation project with cryo or live dispatch depending on cohort timing and geography.
How do I request a quote for Hr?
Use the catalog inquire buttons or the request quote form. Include your allele goal, Cre plan if any, strain background, and cohort size. A PhD led team responds with pricing, milestones, and the fastest path to experimental animals.
Related models and routes
Citations
- Nitric oxide drives proteomic diversity through alternative splicing
- S100A4-lineage cells contribute modestly to angiotensin II-mediated thoracic aortic aneurysms through angiotensin II type 1a receptor in mice
- Improving anti-CTLA-4 therapies through peptide masking and fragment crystallizable non‑fucosylation: preclinical characterization of three novel antibodies
- Unbalanced chromatin binding of Polycomb complexes drives neurodevelopmental disorders
- Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling
Breed this line with ITL
Send the Hr Immunodeficient line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.