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Lepr Conditional Knockout, Knockin, Knockout mouse models
Browse 6 Lepr mouse models including conditional knockout, knockin, knockout variants from ingenious targeting laboratory. Available as Lepr conditional knockout mouse, Lepr knockin mouse, Lepr knockout mouse. Contact us for availability and fast turnaround.
Available Lepr catalog models
6 Lepr lines with QC documentation and technical support. Lepr floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.
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Lepr-Flox
CKOCKO, Disease Model
These mice carry loxP sites flanking exon 4 of Lepr gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Lepr gene.
Sperm CryopreservedCKO 200116 - Order
Lepr-RSR-CreERT2
KICre/Dre Toolbox
rox-stop-rox-CreERT2-WPRE-polyA expression cassette was knocked into the Lepr gene.
Sperm CryopreservedKI 210112 - Order
Lepr-G/T(Intron17)
KIPoint Mutation
G/T was knocked into exon19 of the Lepr gene(c.109053 G>T).
Embryo CryopreservedKI 230477 - Order
Lepr-G/T(Intron17)(BALB/c)
KIPoint Mutation
G/T was knocked into exon19 of the Lepr gene(c.109052 G>T).
In DevelopmentKI 230478 - Order
Lepr-g.G109052T
KIPoint Mutation, Disease Model
A point mutation was introduced to exon 19 (c.109052 G>T) via a recombineering strategy. Homozygous mutants are hyperphagic, low-activity, poorly cold-adapted, sterile and have enhanced fat conversion.
Embryo CryopreservedKI 00001 - Order
Lepr-KO
KOKO, Disease Model
Exon 5 of Lepr gene was deleted to generate Lepr knockout mice.
Sperm CryopreservedKO 190663
Looking for a Lepr mouse model?
We have 6 Lepr models available — including Conditional Knockout, Knockin, Knockout types. Contact us today for current availability and our fastest turnaround options. All models come with full QC documentation and technical support.
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Order catalog modelAbout Lepr Mouse Model Types
A Lepr knockout mouse has the Lepr gene permanently inactivated, enabling loss of function studies. A Lepr conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Lepr, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints. Lepr knockin models carry a precisely inserted sequence at the Lepr locus, useful for reporter, tag, or humanization studies.
Modifications available
Jump to catalog backed pages for Lepr organized by modification type. Each URL is indexable and matches common search patterns.
Tissue-specific options
Catalog backed tissue and driver restricted routes for Lepr.
Breed this line with ingenious targeting laboratory
Send the Lepr line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.