Myoc Conditional Knockout Mouse
Since 1998, ingenious targeting laboratory has delivered 2,800+ projects with 100% germline transmission guarantee and 800+ peer reviewed publications.
Myoc is a common request for conditional knockout mouse models. Ingenious targeting laboratory designs and delivers the line to your study specification with documented milestones.
Get a Quote in 24 HoursWhat Myoc Conditional Knockout mouse models are available?
ingenious targeting laboratory designs and generates Myoc conditional knockout mouse models to your specification. Quotes return in about 24 hours with documented germline transmission and strict United States QC guidelines.
Scientific design
Myoc is a well studied locus in mouse genetics. Allele design follows your phenotype goals and what the published landscape already shows for this gene.
1 existing allele are indexed for Myoc, including 1 knockout. Where the published set lacks the modification you need, ingenious targeting laboratory builds that allele with documented germline transmission.
Conditional alleles place loxP sites around critical exons and keep reading frame intact until Cre excision. FRT flanked derivatives (tm1a to tm1c to tm1d) let you convert before breeding to your Cre driver. We confirm critical exon choice and regulatory element preservation before germline transmission.
Quotes return in about 24 hours with milestones, pricing, and options for cryo or live dispatch.
What researchers say
“Ingenious targeting laboratory delivered exactly the floxed allele we designed, with clear milestones and germline confirmed founders.”
“The team translated our humanization requirements into a knockin strategy we could breed and phenotype on schedule.”
“Clear communication on allele design and germline transmission made our conditional knockout program straightforward to execute.”
Selected publications
- Redox-Resistant SERCA Attenuates Oxidant-Stimulated Mitochondrial Calcium and Apoptosis in Cardiac Myocytes and Pressure Overload-Induced Myocardial Failure in Mice
- Restricting mitochondrial GRK2 post-ischemia confers cardioprotection by reducing myocyte death and maintaining glucose oxidation
- IL-23R Signaling Plays No Role in Myocardial Infarction
- Inactivation of the Glucose-Dependent Insulinotropic Polypeptide Receptor Improves Outcomes following Experimental Myocardial Infarction
- Abnormal striatal plasticity in a DYT11/SGCE myoclonus dystonia mouse model is reversed by adenosine A2A receptor inhibition
FAQ
What Myoc Conditional Knockout mouse models are available?
When Myoc Conditional Knockout lines are in catalog, we ship from inventory. If your configuration is not listed, we design the allele to order. Common paths include conditional knockout, constitutive knockout, humanized, knockin, and transgenic options, with documented germline transmission and United States QC.
Is Myoc knockout embryonic lethal in mice?
It depends on background and allele design. Some Myoc germline knockouts are viable. Others need conditional alleles or mixed backgrounds. We review publications and our own experience, then recommend floxed versus null before you commit.
Which Cre driver is best for experiments?
Driver choice depends on onset timing, recombination efficiency, and known leak. We map your organ and cell type to a short list of proven Cre lines, then talk through reporter crosses and controls. We favor drivers with strong community validation for your tissue.
Do you ship live Myoc animals?
When catalog lines are live, we ship with health certificates and QC documentation. If your exact combo is not listed, we quote a generation project with cryo or live dispatch depending on cohort timing and geography.
How do I request a quote for Myoc?
Use the catalog inquire buttons or the request quote form. Include your allele goal, Cre plan if any, strain background, and cohort size. A PhD led team responds with pricing, milestones, and the fastest path to experimental animals.