What Piezo1 Conditional Knockout mouse models are available?

When Piezo1 Conditional Knockout lines are in catalog, we ship from inventory. If your configuration is not listed, we design the allele to order. Common paths include conditional knockout, constitutive knockout, humanized, knockin, and transgenic options, with documented germline transmission and United States QC.

Is Piezo1 knockout embryonic lethal in mice?

It depends on background and allele design. Some Piezo1 germline knockouts are viable. Others need conditional alleles or mixed backgrounds. We review publications and our own experience, then recommend floxed versus null before you commit.

Which Cre driver is best for experiments?

Driver choice depends on onset timing, recombination efficiency, and known leak. We map your organ and cell type to a short list of proven Cre lines, then talk through reporter crosses and controls. We favor drivers with strong community validation for your tissue.

Do you ship live Piezo1 animals?

When catalog lines are live, we ship with health certificates and QC documentation. If your exact combo is not listed, we quote a generation project with cryo or live dispatch depending on cohort timing and geography.

How do I request a quote for Piezo1?

Use the catalog inquire buttons or the request quote form. Include your allele goal, Cre plan if any, strain background, and cohort size. A PhD led team responds with pricing, milestones, and the fastest path to experimental animals.

●6 Models Available

READY TO SHIP!

LIVE · SPERM · EMBRYO · DEVELOPING

Piezo1 Conditional Knockout, Knockin, Knockout mouse models

Browse 6 Piezo1 mouse models including conditional knockout, knockin, knockout variants — in stock and ready to ship from ingenious targeting laboratory. Available as Piezo1 conditional knockout mouse, Piezo1 knockin mouse, Piezo1 knockout mouse, Piezo1 xenograft-applicable mouse. Request a quote within 24 hours.

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Available Piezo1 catalog models

6 Piezo1 lines with QC documentation and technical support. Piezo1 floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.

Piezo1-Flox
CKO
CKO
These mice carry loxP sites flanking exon 4-5 of Piezo1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Piezo1 gene.
LiveCKO 200275
Order
Piezo1-CreERT2
KI
Cre/Dre Toolbox
This tamoxifen-inducing Piezo1-CreERT2 tool mouse model was established by inserting a 2A-CreERT2 co-expression cassette into the Piezo1 gene stop codon site .
LiveKI 18048
Order
Piezo1-KO
KO
KO
Exon 4-5 of Piezo1 gene was deleted to generate Piezo1 knockout mice.
F0 Embryo CryopreservedKO 225123
Order
Piezo1-Flox/Krt5-IRES-CreERT2
XA
CKO
The Piezo1-Flox (CKO 200275) was crossed with Krt5-IRES-CreERT2(KI 200168) to generate Piezo1-Flox/Krt5-IRES-CreERT2 mice.
In DevelopmentXA 263069
Order
Piezo1-Flox/Sp7-F2A-CreERT2
XA
CKO, Cre/Dre Toolbox
The Piezo1-Flox (CKO 200275) was crossed with Sp7-F2A-CreERT2(KI 232333) to generate Piezo1-Flox/Sp7-F2A-CreERT2 mice.
In DevelopmentXA 253121
Order
Piezo1-Flox/Cdh5-2A-CreERT2
XA
CKO, Cre/Dre Toolbox
The Piezo1-Flox (CKO 200275) was crossed with Cdh5-2A-CreERT2(KI 200173) to generate Piezo1-Flox/Cdh5-2A-CreERT2 mice.
Sperm CryopreservedXA 251729
Order

Looking for a Piezo1 mouse model?

We have 6 Piezo1 models in stock — including Conditional Knockout, Knockin, Knockout types. In stock and ready to ship this week. All models come with full QC documentation, health certificates, and dedicated technical support.

Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.

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Models Available

Model Types

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Included

QC Documentation

About Piezo1 Mouse Model Types

A Piezo1 knockout mouse has the Piezo1 gene permanently inactivated, enabling loss of function studies. A Piezo1 conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Piezo1, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints. Piezo1 knockin models carry a precisely inserted sequence at the Piezo1 locus, useful for reporter, tag, or humanization studies.

Knockout Mouse Models Conditional Knockout Mouse Models Knockin Mouse Models Mouse Model Generation Services

Modifications available

Jump to catalog backed pages for Piezo1 organized by modification type. Each URL is indexable and matches common search patterns.

Piezo1 Conditional Knockout Piezo1 Knockin Piezo1 Knockout Piezo1 Xenograft-Applicable Piezo1 cDNA Knockin Piezo1 Epitope Tag Knockin Piezo1 Humanized Piezo1 Inducible Knockout Piezo1 Overexpression / Safe Harbor Piezo1 Reporter

Related Gene Targets

Pierce1 Pierce1(1700007K13Rik)Piezo2

Breed this line with ingenious targeting laboratory

Send the Piezo1 line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.

Mouse Models

Two paths. One scientific team.

Search 14,774+ study ready strains, or commission the exact knockout, knockin, or humanized model your program requires.

Live colonies

Piezo1 models ready to ship

Get a confirmed quote in 24 hours. All Piezo1 models ship with full QC documentation, health certificates, and lifetime technical support.

Piezo1Study ready strains in catalog

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Model generation

Need a knockout, knockin, or humanized line?

Specialized conventional and conditional knockouts
Knockins including point mutations, cDNA insertions, and epitope tags
Humanized models, including partial and full gene replacements
Targeted transgenesis in safe harbor loci
Inducible/reversible alleles using advanced recombinase techniques

The same U.S. scientific team designs and delivers your allele when it is not on the shelf. 2,800+ custom models generated since 1998. 100% germline transmission guarantee.

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