What Piezo2 Conditional Knockout mouse models are available?

When Piezo2 Conditional Knockout lines are in catalog, we ship from inventory. If your configuration is not listed, we design the allele to order. Common paths include conditional knockout, constitutive knockout, humanized, knockin, and transgenic options, with documented germline transmission and United States QC.

Is Piezo2 knockout embryonic lethal in mice?

It depends on background and allele design. Some Piezo2 germline knockouts are viable. Others need conditional alleles or mixed backgrounds. We review publications and our own experience, then recommend floxed versus null before you commit.

Which Cre driver is best for experiments?

Driver choice depends on onset timing, recombination efficiency, and known leak. We map your organ and cell type to a short list of proven Cre lines, then talk through reporter crosses and controls. We favor drivers with strong community validation for your tissue.

Do you ship live Piezo2 animals?

When catalog lines are live, we ship with health certificates and QC documentation. If your exact combo is not listed, we quote a generation project with cryo or live dispatch depending on cohort timing and geography.

How do I request a quote for Piezo2?

Use the catalog inquire buttons or the request quote form. Include your allele goal, Cre plan if any, strain background, and cohort size. A PhD led team responds with pricing, milestones, and the fastest path to experimental animals.

●5 Models Available

READY TO SHIP!

LIVE · SPERM · IN PRODUCTION

Piezo2 Conditional Knockout, Knockin, Knockout mouse models

Browse 5 Piezo2 mouse models including conditional knockout, knockin, knockout variants — in stock and ready to ship from ingenious targeting laboratory. Available as Piezo2 conditional knockout mouse, Piezo2 knockin mouse, Piezo2 knockout mouse, Piezo2 xenograft-applicable mouse. Request a quote within 24 hours.

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Available Piezo2 catalog models

5 Piezo2 lines with QC documentation and technical support. Piezo2 floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.

Piezo2-Flox
CKO
CKO
These mice carry loxP sites flanking exon 43-45 of Piezo2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Piezo2 gene.
LiveCKO 200127
Order
Piezo2-2A-Cre
KI
Cre/Dre Toolbox
The 2A-Cre expression cassette was knocked into the Piezo2 gene stop codon site.
In production — inquireKI 261678
Order
Piezo2-2xMyr-mGreenLantern-3xFLAG-IRES-CrexER
KI
Cre/Dre Toolbox, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent)
The Kozak-2xMyr-mGreenLantern-3xFLAG-IRES-Cre-rox-ERT2-rox-WPRE-pA expression cassette was knocked into the Piezo2 gene start codon site.
LiveKI 260333
Order
Piezo2-KO
KO
KO
This Piezo2 knockout mouse model was generated by knocking out the exon 42 region of the Piezo2.
Sperm CryopreservedKO 190343
Order
Piezo2-Flox/Col1a2-2A-Cre
XA
CKO, Cre/Dre Toolbox
The Piezo2-Flox (CKO 200127) was crossed with Col1a2-2A-Cre(KI 215043) to generate Piezo2-Flox/Col1a2-2A-Cre mice.
Sperm CryopreservedXA 251718
Order

Looking for a Piezo2 mouse model?

We have 5 Piezo2 models in stock — including Conditional Knockout, Knockin, Knockout types. In stock and ready to ship this week. All models come with full QC documentation, health certificates, and dedicated technical support.

Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.

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Models Available

Model Types

24 hrs

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Included

QC Documentation

About Piezo2 Mouse Model Types

A Piezo2 knockout mouse has the Piezo2 gene permanently inactivated, enabling loss of function studies. A Piezo2 conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Piezo2, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints. Piezo2 knockin models carry a precisely inserted sequence at the Piezo2 locus, useful for reporter, tag, or humanization studies.

Knockout Mouse Models Conditional Knockout Mouse Models Knockin Mouse Models Mouse Model Generation Services

Modifications available

Jump to catalog backed pages for Piezo2 organized by modification type. Each URL is indexable and matches common search patterns.

Piezo2 Conditional Knockout Piezo2 Knockin Piezo2 Knockout Piezo2 Xenograft-Applicable Piezo2 cDNA Knockin Piezo2 Epitope Tag Knockin Piezo2 Humanized Piezo2 Inducible Knockout Piezo2 Overexpression / Safe Harbor Piezo2 Reporter

Related Gene Targets

Pierce1 Pierce1(1700007K13Rik)Piezo1

Breed this line with ingenious targeting laboratory

Send the Piezo2 line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.

Mouse Models

Two paths. One scientific team.

Search 14,774+ study ready strains, or commission the exact knockout, knockin, or humanized model your program requires.

Live colonies

Piezo2 models ready to ship

Get a confirmed quote in 24 hours. All Piezo2 models ship with full QC documentation, health certificates, and lifetime technical support.

Piezo2Study ready strains in catalog

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Model generation

Need a knockout, knockin, or humanized line?

Specialized conventional and conditional knockouts
Knockins including point mutations, cDNA insertions, and epitope tags
Humanized models, including partial and full gene replacements
Targeted transgenesis in safe harbor loci
Inducible/reversible alleles using advanced recombinase techniques

The same U.S. scientific team designs and delivers your allele when it is not on the shelf. 2,800+ custom models generated since 1998. 100% germline transmission guarantee.

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