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R26 Knockin mouse models

Knockin designs at R26 support head to head comparisons between wild type and modified alleles because regulatory DNA stays in place.

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What R26 Knockin mouse models are available?

ingenious targeting laboratory offers 298 distinct R26 knockin catalog mouse models. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.

Model Availability

298 Ready Catalog Lines

Allele Class Options

Knockin

Quality Control Standards

Documented Germline Transmission

Catalog table

ModelTypeCategoryAvailabilityCatalog #Action
R26-CAG-LSL-Foxk1-2A-tdtomatoKIOverexpression, Fluorescent ModelEMBRYOKI 200314Inquire
A CAG-LSL-Foxk1-2A-tdtomato-WPRE-pA expression cassette was knocked into the Rosa26 locus.
R26-CAG-LSL-ASGR1-2A-ASGR2KIOtherDEVELOPINGKI 264070Inquire
CAG-LSL-Kozak-ASGR1-P2A-ASGR2-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-CDK3KIOtherDEVELOPINGKI 263582Inquire
CAG-LSL-Kozak-CDK3-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-hSOX2-IRES-Luc-2A-EGFP/Kras-LSL-G12DKIOverexpression, Fluorescent Model, Target-Humanized, Disease ModelSPERMKI 234153Inquire
The R26-CAG-LSL-hSOX2-IRES-Luc-2A-EGFP(KI 210138) was crossed with Kras-LSL-G12D(KI 190003) to generate R26-CAG-LSL-hSOX2-IRES-Luc-2A-EGFP/Kras-LSL-G12D mice.
R26-CAG-LSL-Luc-2A-EGFP/Trp53-Flox/Kras-LSL-G12DKICKO, Point Mutation, Overexpression, Fluorescent Model, Disease ModelEMBRYOKI 234519Inquire
The R26-CAG-LSL-Luc-2A-EGFP(KI 190095) was crossed with Trp53-Flox/Kras-LSL-G12D(CKO 233079) to generate R26-CAG-LSL-Luc-2A-EGFP/Trp53-Flox/Kras-LSL-G12D mice.
R26-CAG-LSL-AAVRKIOverexpression, Disease ModelEMBRYOKI 190099Inquire
These mice harbor a SA-FRT-2XpA-CAG-FRT-LSL-AAVR-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hRHOA*Y42C-IRES-tdTomatoKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelSPERMKI 200048Inquire
These mice harbor a SA-FRT-2xpolyA-CAG-FRT-RHOA(Y42C)-IRES-tdTomato-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-Vegfc-IRES-Luc-2A-tdTomatoKIOverexpression, Fluorescent Model, Disease ModelEMBRYOKI 200039Inquire
These mice harbor a SA-Frt-2xpA-CAG-Frt-LSL-Vegfc-IRES-Luc-2A-tdTomato-Wpre-pA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-Hgf-IRES-Luc-2A-tdTomatoKIOverexpression, Fluorescent Model, Disease ModelSPERMKI 200037Inquire
These mice harbor a SA-FRT-2xpolyA-CAG-FRT-loxp-stop-loxp-Hgf-IRES-Luciferase-2A-tdTomato-wpre-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hPLA2R1-IRES-EGFPKIOverexpression, Fluorescent Model, Target-HumanizedLIVEKI 220264Inquire
CAG-LSL-hPLA2R1-IRES-EGFP expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-hMSLN CDS-IRES-LucKIOverexpression, Fluorescent Model, Target-HumanizedSPERMKI 225094Inquire
CAG-LSL-hMSLN CDS-IRES-Luciferase-WPRE-pA expression cassette was knocked into the Rosa26 locus.
R26-CAG-LSL-Mettl14-IRES-EGFPKIOverexpression, Fluorescent ModelEMBRYOKI 190017Inquire
These mice harbor a SA-2xpolyA-CAG-LSL-3xFLAG-Mettl14-IRES-EGFP-Wpre-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hHER2*ex20ins-IRES-Luc-2A-EGFPKIOverexpression, Fluorescent Model, Target-Humanized, Disease ModelSPERMKI 190071Inquire
These mice harbor a CAG-LSL-ERBB2(exon20 insertion)-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hEGFR-IRES-Luc-2A-tdTomatoKIOverexpression, Fluorescent Model, Target-Humanized, Disease ModelEMBRYOKI 190066Inquire
These mice harbor a CAG-LSL-EGFR-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hTERT-IRES-Luc-2A-EGFPKIOverexpression, Fluorescent Model, Target-HumanizedLIVEKI 18035Inquire
A CAG promoter-loxp-stop-loxp-V5-TERT-IRES-Luciferase-2A-EGFP-WPRE-polyA expression cassette was inserted at the Rosa26 locus site.
R26-CAG-LSL-Dusp12KIOverexpressionEMBRYOKI 18038Inquire
A CAG promoter-LSL-Kozak-Dusp12-3XFlag-Wpre-pA expression cassette was inserted at the Rosa26 locus site.
R26-CAG-LSL-GqDREADD(hM3Dq)-2A-mCitrineKIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)LIVEKI 190106Inquire
These mice harbor a CAG-LSL-HA-GiDREADD(hM3Dq)-P2A-mCitrine-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-GiDREADD(hM4Di)-2A-mCitrineKIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)LIVEKI 190093Inquire
These mice harbor a CAG-LSL-HA-GiDREADD(hM4Di)-2A-mCitrine-WPRE-pA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-Wtap-IRES-EGFPKIOverexpression, Fluorescent ModelEMBRYOKI 190058Inquire
These mice harbor a CAG-LSL-Wtap-3xFLAG-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-Ythdf1-IRES-EGFPKIOverexpression, Fluorescent ModelSPERMKI 190061Inquire
These mice harbor a CAG-LSL-3xFLAG-Ythdf1-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-Ythdc2-IRES-EGFPKIOverexpression, Fluorescent ModelEMBRYOKI 190060Inquire
These mice harbor a CAG-LSL-Ythdc2-3xFLAG-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hEZH2*Y646N-IRES-Luc-2A-tdTomatoKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelSPERMKI 190073Inquire
These mice harbor a CAG-LSL-EZH2(Y646N)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.
R26-SA-rtTAKIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)EMBRYOKI 18025Inquire
These mice harbor a SA-V5-M2rtTA-FRT-WPRE-FRT-polyA-attb-PGK-Neo-polyA-attp expression cassette in mouse Rosa26 loci homologous recombination.
R26-CAG-LSL-mCherry-EGFP-LC3KIOverexpression, Fluorescent ModelLIVEKI 00124Inquire
The CAG promoter-loxp-stop-loxp-mCherry-EGFP-Map1lc3a-WPRE-polyA expression cassette was inserted into the Rosa26 gene locus by homologous recombination. Map1lc3a, also known as LC3, is a widely expressed autophagic vesicle-specific marker. There was no abnormality in heterozygous mice. The presence of the loxp-stop-loxp expression cassette prevented the transcription of the downstream target gene LC3. After mating with Cre mice, LC3 gene is driven by the CAG promoter to express mCherry and EGFP in a pH-dependent manner in phagocytic cells after ischemic injury in the progeny double positive mice. The two co-expressed fluorescent signals vary depending on the acidic environment of the autophagic vesicles within the cell. mCherry is stable in an acidic environment (pKa 4.5), and quenching occurs in the acidic environment (pKa 5.9) of EGFP in lysosomes. In the autophagy vesicles with higher pH, the fluorescence of GFP and mCherry superimposed on yellow fluorescence; while in the lower pH lysosome, EGFP was quenched and only red fluorescence signal was detected. It can be used to label and track LC3 and study the origin, progression and disappearance of autophagy in various tissues after ischemic injury.
R26-CAG-LSL-hEML4/ALK*F1174L-Luc-tdTomatoKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelEMBRYOKI 190010Inquire
A SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-Luciferase-2A-tdTomato-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the EML4-ALK(F1174L) protein.
R26-LSL-hEZH2-IRES-Luc-2A-tdTomatoKIOverexpression, Fluorescent Model, Target-HumanizedSPERMKI 18053Inquire
A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human EZH2 cDNA-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that human EZH2 could be expressed after exposure to Cre recombinase.
R26-CAG-LSL-hNFE2L2*G81S-IRES-Luc-2A-tdTomatoKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelEMBRYOKI 190077Inquire
These mice harbor a CAG-LSL-NFE2L2(G81S)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hPIK3CA*H1047R-IRES-Luc-2A-tdTomatoKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelLIVEKI 190065Inquire
These mice harbor a CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hEGFR*L858R/T790M/C797S-IRES-Luc-2A-tdTomatoKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelLIVEKI 190067Inquire
These mice harbor a CAG-LSL-EGFR (L858R-T790M-C797S)-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hPIK3CA*H1047R-IRES-Luc-2A-tdTomato/R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc/Krt14-CreERT2KIPoint Mutation, Overexpression, Cre/Dre Toolbox, Fluorescent Model, Target-HumanizedEMBRYOKI 234954Inquire
The R26-CAG-LSL-hPIK3CA*H1047R-IRES-Luc-2A-tdTomato(KI 190065)was crossed with R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc/Krt14-CreERT2(KI 234663)to generate Trp53-LSL-R172H/R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc/Krt14-CreERT2 mice.
R26-CAG-LSL-Kras*G12C-IRES-Luc/R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc/Krt14-CreERT2KIPoint Mutation, Overexpression, Cre/Dre Toolbox, Fluorescent ModelLIVEKI 235082Inquire
The R26-CAG-LSL-Kras*G12C-IRES-Luc (KI 200323) was crossed with R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc/Krt14-CreERT2 (KI 234663) to generate R26-CAG-LSL-Kras*G12C-IRES-Luc/R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc/Krt14-CreERT2 mice.
R26-CAG-LSL-SLFN12KIOtherDEVELOPINGKI 263534Inquire
CAG-LSL-Kozak-SLFN12-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Crlf1KIOtherDEVELOPINGKI 263525Inquire
CAG-LSL-Kozak-Crlf1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-hCRLF1KITarget-HumanizedDEVELOPINGKI 263524Inquire
CAG-LSL-Kozak-hCRLF1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-SV40T-IRES-hTERTKITarget-HumanizedDEVELOPINGKI 263308Inquire
CAG-LSL-Kozak-SV40T-IRES-hTERT-pA expression cassette was knocked into the the Rosa26 locus.
R26-LSL-SV40T-IRES-hTERTKITarget-HumanizedDEVELOPINGKI 263307Inquire
SA-LSL-Kozak-SV40T-IRES-hTERT-pA expression cassette was knocked into the the Rosa26 locus.
R26-hCD58KITarget-Humanized, OverexpressionDEVELOPINGKI 263230Inquire
hCD58 expression cassette was knocked into the the Rosa26 locus.
R26-U6-gRNA(Fah)-U6-gRNA(Rag2)-U6-gRNA(IL2rg)-CAG-LSL-Cas9-2A-EGFPKIOtherDEVELOPINGKI 263216Inquire
U6-gRNA(Fah)-U6-gRNA(Rag2)-U6-gRNA(IL2rg)-CAG-LSL-Cas9-2A-EGFP expression cassette was knocked into the the Rosa26 locus.
R26-attBKIOverexpressionDEVELOPINGKI 263215Inquire
attB expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-LucKIOther Toolbox (non-Cre, non-Fluorescent), OverexpressionDEVELOPINGKI 263211Inquire
CAG-LSL-Kozak-Luciferase-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-hINSRKIOverexpression, Target-HumanizedDEVELOPINGKI 262954Inquire
CAG-LSL-Kozak-hINSR-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-hINSR-D734AKIOverexpression, Target-Humanized, Point MutationDEVELOPINGKI 262953Inquire
CAG-LSL-Kozak-hINSR-D734A-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Mst1r-M1231TKIOverexpressionDEVELOPINGKI 262920Inquire
CAG-LSL-Mst1r-M1231T-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Ube2v1KIOverexpressionIN PRODUCTIONKI 262450Inquire
CAG-LSL-Kozak-Ube2v1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-RSR-LSL-PhiYFPKIFluorescent ModelIN PRODUCTIONKI 262435Inquire
CAG-RSR-LSL-Kozak-PhiYFP-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-RSR-FSF-loxP-tdTomato-loxP-mNeonGreenKIOverexpression, Fluorescent ModelIN PRODUCTIONKI 261790Inquire
CAG-RSR-FSF-loxP-Kozak-tdTomato-WPRE-pA-loxP-Kozak-mNeonGreen-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Slco1a1-tdTomato-LSL-CAGKIOverexpression, Fluorescent ModelLIVEKI 260668Inquire
CAG-LSL-Kozak-Slco1a1-pA-INS-INS-pA-tdTomato-Kozak-lox2272-STOP-lox2272-CAG expression cassette was knocked into the the Rosa26 locus.
R26-2xpA-CAG-LSL-hPNPLA3-IRES-EGFPKIOverexpression, Fluorescent Model, Target-HumanizedIN PRODUCTIONKI 260672Inquire
SA-FRT-2xpA-CAG-FRT-LSL-Kozak-hPNPLA3-IRES-EGFP-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-MitoTimerKIOverexpression, Fluorescent ModelIN PRODUCTIONKI 260078Inquire
CAG-LSL-Kozak-MitoTimer-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-mFerritin-Slco1a1-RSR-CAGKIOverexpressionIN PRODUCTIONKI 260038Inquire
CAG-LSL-Kozak-mFerritin-pA-INS*2-pA-Slco1a1-Kozak-RSR-CAG expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-FKBPv-CASP8-FLAG-IRES-EGFPKIOverexpression, Fluorescent ModelIN PRODUCTIONKI 260027Inquire
SA-FRT-2xpA-CAG-FRT-LSL-Kozak-Myr-FKBPv-Linker-CASP8-3×FLAG-IRES-EGFP-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Tet2KIOverexpressionIN PRODUCTIONKI 254274Inquire
CAG-LSL-Kozak-Tet2-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Nat10KIOverexpressionIN PRODUCTIONKI 254273Inquire
CAG-LSL-Kozak-Nat10-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Slc23a2KIOverexpressionLIVEKI 254271Inquire
CAG-LSL-Kozak-Slc23a2-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Rgs1KIOverexpressionIN PRODUCTIONKI 254270Inquire
CAG-LSL-Kozak-Rgs1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Piezo1KIOverexpressionLIVEKI 254269Inquire
CAG-LSL-Kozak-Piezo1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-OgtKIOverexpressionLIVEKI 254268Inquire
CAG-LSL-Kozak-Ogt-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Cdkn2a(p16)KIOverexpressionLIVEKI 254267Inquire
CAG-LSL-Kozak-Cdkn2a(p16)-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Icam1KIOverexpressionIN PRODUCTIONKI 254266Inquire
CAG-LSL-Kozak-Icam1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Tgfbr2KIOverexpressionIN PRODUCTIONKI 254261Inquire
CAG-LSL-Kozak-Tgfbr2-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Npc1KIOverexpressionIN PRODUCTIONKI 254260Inquire
CAG-LSL-Kozak-Npc1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Cdkn1aKIOverexpressionIN PRODUCTIONKI 254259Inquire
CAG-LSL-Kozak-Cdkn1a-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Cd36KIOverexpressionIN PRODUCTIONKI 254258Inquire
CAG-LSL-Kozak-Cd36-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Arg1KIOverexpressionLIVEKI 254257Inquire
CAG-LSL-Kozak-Arg1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-ApcKIOverexpressionIN PRODUCTIONKI 254256Inquire
CAG-LSL-Kozak-Apc-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-EGFP-ABEKIOverexpression, Fluorescent ModelLIVEKI 254254Inquire
CAG-Kozak-EGFP*Q81*-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Twist1KIOverexpressionIN PRODUCTIONKI 254253Inquire
CAG-LSL-Kozak-Twist1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-RbpjKIOverexpressionIN PRODUCTIONKI 254252Inquire
CAG-LSL-Kozak-Rbpj-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Ptk2KIOverexpressionIN PRODUCTIONKI 254251Inquire
CAG-LSL-Kozak-Ptk2-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Spp1KIOverexpressionLIVEKI 254250Inquire
CAG-LSL-Kozak-Spp1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Ifnar1KIOverexpressionIN PRODUCTIONKI 254249Inquire
CAG-LSL-Kozak-Ifnar1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Gja1KIOverexpressionLIVEKI 254248Inquire
CAG-LSL-Kozak-Gja1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Runx1KIOverexpressionIN PRODUCTIONKI 254247Inquire
CAG-LSL-Kozak-Runx1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Trim25KIOverexpressionIN PRODUCTIONKI 254246Inquire
CAG-LSL-Kozak-Trim25-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Slc16a1KIOverexpressionLIVEKI 254245Inquire
CAG-LSL-Kozak-Slc16a1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Nr1d1KIOverexpressionIN PRODUCTIONKI 254244Inquire
CAG-LSL-Kozak-Nr1d1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Mpc1KIOverexpressionIN PRODUCTIONKI 254243Inquire
CAG-LSL-Kozak-Mpc1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Lag3KIOverexpressionLIVEKI 254242Inquire
CAG-LSL-Kozak-Lag3-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-ApoeKIOverexpressionIN PRODUCTIONKI 254241Inquire
CAG-LSL-Kozak-Apoe-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Htr1aKIOverexpressionIN PRODUCTIONKI 254240Inquire
CAG-LSL-Kozak-Htr1a-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Adrb2KIOverexpressionIN PRODUCTIONKI 254239Inquire
CAG-LSL-Kozak-Adrb2-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Acsl4KIOverexpressionIN PRODUCTIONKI 254238Inquire
CAG-LSL-Kozak-Acsl4-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Slc6a6KIOverexpressionIN PRODUCTIONKI 254237Inquire
CAG-LSL-Kozak-Slc6a6-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Igf1KIOverexpressionLIVEKI 254236Inquire
CAG-LSL-Kozak-Igf1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Glp1rKIOverexpressionIN PRODUCTIONKI 254235Inquire
CAG-LSL-Kozak-Glp1r-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Lrg1KIOverexpressionLIVEKI 254230Inquire
CAG-LSL-Kozak-Lrg1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Ramp1KIOverexpressionIN PRODUCTIONKI 254229Inquire
CAG-LSL-Kozak-Ramp1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Gdf15KIOverexpressionIN PRODUCTIONKI 254228Inquire
CAG-LSL-Kozak-Gdf15-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Cx3cr1KIOverexpressionIN PRODUCTIONKI 254227Inquire
CAG-LSL-Kozak-Cx3cr1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Il4raKIOverexpressionIN PRODUCTIONKI 254226Inquire
CAG-LSL-Kozak-Il4ra-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Cd44KIOverexpressionIN PRODUCTIONKI 254225Inquire
CAG-LSL-Kozak-Cd44-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Il15raKIOverexpressionIN PRODUCTIONKI 254220Inquire
CAG-LSL-Kozak-Il15ra-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-MetrnlKIOverexpressionSPERMKI 254108Inquire
Metrnl expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-RSR-ApoeKIOverexpressionLIVEKI 253900Inquire
CAG-LSL-RSR-Kozak-Apoe-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-chPLA2R1-IRES-EGFP(BALB/c)KIOverexpression, Fluorescent ModelLIVEKI 253775Inquire
CAG-LSL-Kozak-chPLA2R1-IRES-EGFP-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-H2B-EBFP-CAG-RSR-tdTomatoKIOverexpression, Fluorescent ModelLIVEKI 253635Inquire
CAG-LSL-Kozak-H2B-EBFP-pA-CAG-RSR-Kozak-tdTomato-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-iCasp9KIOverexpressionIN PRODUCTIONKI 253332Inquire
CAG-LSL-Kozak-iCasp9-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-hPLA2R1(BALB/c)KIOverexpression, Target-HumanizedLIVEKI 253107Inquire
CAG-loxP-STOP-loxP-Kozak-hPLA2R1-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-loxP-tdTomato-3xpA-lox2272-Luc-IRES-TAG-loxP-lox2272KIOverexpression, Fluorescent ModelIN PRODUCTIONKI 253000Inquire
SA-loxP-tdTomato-3xpA-lox2272-WPRE-pA-Luciferase-IRES-TAG-loxP-lox2272 expression cassette was knocked into the the Rosa26 locus.
R26-EGFP(M-NSG,2)KIOverexpression, Fluorescent Model, ImmunodeficientLIVEKI 252815Inquire
CAG-EGFP-WPRE-polyA expression cassette was knocked into the the Rosa26 locus.
R26-FLEX-DUX4KIOverexpressionDEVELOPINGKI 252778Inquire
SA-loxP-STOP-lox2272-DUX4-loxP-lox2272 expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-C3a-IRES-EGFPKIOverexpression, Fluorescent ModelSPERMKI 252689Inquire
CAG-loxP-STOP-loxP-Kozak-C3a-IRES-EGFP-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-C5a-IRES-tdTomatoKIOverexpression, Fluorescent ModelLIVEKI 252688Inquire
CAG-loxP-STOP-loxP-Kozak-C5a-IRES-tdTomato-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-SA-2xpA-CAG-LSL-hEGFR*del19*T790MKIPoint Mutation, Overexpression, Target-HumanizedLIVEKI 252661Inquire
SA-2xpA-CAG-loxP-STOP-loxP-Kozak-hEGFR*del19*T790M-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-hEGFR*del19(2)KIPoint Mutation, Overexpression, Target-HumanizedSPERMKI 252642Inquire
CAG-loxP-STOP-loxP-Kozak-hEGFR*del19-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-Insulator-Insulator-CAG-loxP-STOP-lox2272-mCitrine-2A-GqDREADD(hM3Dq)-HA-loxP-lox2272-Insulator-InsulatorKIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)LIVEKI 252625Inquire
Insulator-Insulator-CAG-loxP-STOP-lox2272-mCitrine-P2A-GqDREADD(hM3Dq)-HA-Kozak-loxP-lox2272-WPRE-pA-Insulator-Insulator expression cassette was knocked into the the Rosa26 locus.
R26-U6-gRNA(Trp53)-U6-gRNA(Pten)-U6-gRNA(APC)-CAG-LSL-Cas9-2A-EGFPKIOverexpression, Fluorescent ModelDEVELOPINGKI 252339Inquire
U6-U6-gRNA1(Trp53)-U6-gRNA2(Trp53)-U6-gRNA1(Pten)-U6-gRNA2(Pten)-CAG-LSL-Cas9-2A-EGFP expression cassette was knocked into the the Rosa26 locus.
R26-U6-gRNA(Trp53)-U6-gRNA(Pten)-CAG-LSL-Cas9-2A-EGFPKIOverexpression, Fluorescent ModelDEVELOPINGKI 252338Inquire
R26-U6-gRNA1(Trp53)-U6-gRNA2(Trp53)-U6-gRNA1(Pten)-U6- gRNA2(Pten)-U6-gRNA1(APC)-U6-gRNA2(APC)-CAG-LSL-Cas9-2A-EGFP expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Cdk5-2A-EGFPKIOverexpression, Fluorescent ModelSPERMKI 252112Inquire
CAG-LSL-Kozak-Cdk5-2A-EGFP-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-LSL-RNR-IRES-hFLT3LG-FRT-WPRE-FRT(M-NSG)KIOverexpression, Target-Humanized, ImmunodeficientSPERMKI 242456Inquire
The SA-loxP-STOP-loxP-rox-Neo-rox-IRES-hFLT3LG-FRT-WPRE-FRT-polyA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-mCherry-EGFP-FIS1(mito-QC)KIOverexpression, Fluorescent ModelLIVEKI 242695Inquire
The CAG-LSL-Kozak-mCherry-EGFP-FIS1-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-Cyb5r4KIOverexpressionSPERMKI 241685Inquire
The CAG-LSL-Kozak-Cyb5r4-WPRE-pA expression cassette was knocked into the R26 locus.
R26-hygro-puro-Neo-BSDKIOverexpressionDEVELOPINGKI 241892Inquire
The CMV-GAL4-UAS-hygro-pA-UAS-puro-pA-UAS-Neo-pA-UAS-BSD-pA expression cassette was knocked into the R26 locus.
R26-CAG-Ccr5KIOverexpressionSPERMKI 241910Inquire
The CAG-Kozak-Ccr5-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-RSR-tdTomato-2A-DTRKIOverexpression, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent)LIVEKI 200191Inquire
This mouse was obtained by crossing R26-(CAG-LSL-RSR-tdTomato-2A-DTR) mice with systemic Cre mice.
R26-SA-LSL-DTR-IRES-tdTomatoKIOverexpression, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent)LIVEKI 210136Inquire
A SA-LSL-DTR-IRES-tdTomato expression cassette was knocked into via the Rosa26 locus.
R26-LSL-Notch1C-IRES-nEGFPKIOverexpression, Fluorescent Model, Disease ModelSPERMKI 200036Inquire
These mice harbor a SA-LSL-Notch1C-IRES-nEGFP cassette in the Rosa26 locus generated by homologous recombination.Notch1C (mouse Notch1 ,amino acids 1749–2293)
R26-CAG-LSL-hEGFR*L858R/T790M-IRES-Luc-2A-tdTomatoKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelLIVEKI 190068Inquire
These mice harbor a CAG-LSL-EGFR (L858R-T790M)-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-Luc-tdTomatoKIOverexpression, Fluorescent ModelLIVEKI 18051Inquire
A CAG-loxP STOP-loxP-luci-2A-tdTomato-WPRE-polyA cassette was knocked into the mouse ROSA26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that luciferase and tdTomato fluorescent protein could be expressed for cell tracing.
R26-CAG-Cas9KIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)LIVEKI 00120Inquire
These mice were established by crossing R26-(CAG-LSL-Cas9) and EIIA mice together.
R26-CAG-LSL-Cas9-IRES-LucKIOverexpression, Fluorescent ModelLIVEKI 18002Inquire
These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Cas9 gene followed by IRES-Luciferase coexpression cassette. The targeted mutation was inserted into the Rosa26 locus by homologous recombination.
R26-CAG-Luc-2A-tdTomato(M-NSG)KIOverexpression, Fluorescent Model, ImmunodeficientLIVEKI 233090Inquire
The CAG-Luciferase-2A-tdTomato-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-RSR-tdTomato-2A-DTRKIOverexpression, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent)LIVEKI 190086Inquire
These mice harbor a CAG-LSL-RSR-tdTomato-2A-DTR cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-Alkbh5-IRES-EGFPKIOverexpression, Fluorescent ModelSPERMKI 190054Inquire
These mice harbor a CAG-LSL-Alkbh5-3xFLAG-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-EGFP(3)KIOverexpression, Fluorescent ModelLIVEKI 190090Inquire
These mice harbor a CAG-EGFP-WPRE-polyA cassette in the Rosa26 locus.2 generated by homologous recombination. While R26-CAG-EGFP(Stock No.KI 190088) and R26-CAG-EGFP(2)(Stock No.KI 190089) function similarly to R26-CAG-EGFP(3) mice,for more detailed information please contact our technical advisor.
R26-CAG-LSL-3xNLS-endAsCas12a-3xHA-2xNLS-VPR-IRES-EGFPKIOverexpression, Fluorescent ModelSPERMKI 233616Inquire
The CAG-loxP-STOP-loxP-3xNLS-endAsCas12a-3xHA-2xNLS-VPR-IRES-EGFP-bGH-pA expression cassette was knocked into the R26 locus.
R26-CAG-Thy1KIOverexpressionSPERMKI 232890Inquire
The CAG-Kozak-Thy1-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-loxP-STOP-lox2272-tdTomato-IRES-Eda-loxP-lox2272KIOverexpression, Fluorescent ModelSPERMKI 232907Inquire
The CAG-loxP-STOP-lox2272-pA-WPRE-tdTomato-IRES-Eda-Kozak-loxP-lox2272 expression cassette was knocked into the R26 locus.
R26-LSL-Mito EGFPKIOverexpression, Fluorescent ModelLIVEKI 231934Inquire
The CAG-loxP-STOP-loxP-EGFP-OMM-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-3xNLS-AsCas12a-ultra-3xHA-2xNLS-2A-EGFPKIOverexpression, Fluorescent ModelSPERMKI 233390Inquire
The CAG-loxP-STOP-loxP-3xNLS-AsCas12a-ultra-3xHA-2xNLS-T2A-EGFP-bGH-pA expression cassette was knocked into the R26 locus.
R26-CAG-RSR-ZsGreen-Insulator-CAG-LSL-tdTomatoKIOverexpression, Fluorescent ModelLIVEKI 233483Inquire
The CAG-RSR-ZsGreen-WPRE-pA-Insulator-CAG-LSL-tdTomato-WPRE-pA expression cassette was knocked into the R26 locus.
R26-U6-gRNA(Tgm3)KIOverexpressionDEVELOPINGKI 220496Inquire
U6-gRNA(Tgm3) expression cassette was knocked into the the Rosa26 locus.
R26-pAlb-TK-IRES-Luc-2A-EGFP(NOD-scid)KIOverexpression, Fluorescent Model, ImmunodeficientEMBRYOKI 18040Inquire
These Nod-Scid mice harbor a cassette containing Alb promoter-TK-IRES-luciferase-2A-EGFP-polyA. The targeted mutation was inserted into the Gt(ROSA)26Sor locus.
R26-CAG-LSL-dCas9-SPH-IRES-EGFPKIOverexpression, Fluorescent ModelSPERMKI 250714Inquire
The CAG-LSL-Kozak-dCas9-SPH-IRES-EGFP-WPRE-polyA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-Nrg1KIOverexpressionLIVEKI 250689Inquire
The CAG-LSL-Kozak-Nrg1-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-Lyve1-FLAGKIOverexpressionSPERMKI 251391Inquire
The CAG-LSL-Kozak-Lyve1-FLAG-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-hPROCRKIOverexpression, Target-HumanizedSPERMKI 240013Inquire
The SA-FRT-2xpA-CAG-FRT-LSL-Kozak-hPROCR-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-TrimEKIOverexpressionDEVELOPINGKI 232223Inquire
The CAG-LSL-TrimE expression cassette was knocked into the R26 locus.
R26-CAG-LSL-Tir-D4KIOverexpressionIN PRODUCTIONKI 232222Inquire
The CAG-LSL-Tir-D4 expression cassette was knocked into the R26 locus.
R26-CAG-neo-longstop-linker-neo-longstop-Kras*G12D-FLAG-AID-EGFP-ALFA-tagKIPoint Mutation, Overexpression, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent)IN PRODUCTIONKI 234477Inquire
The CAG-neo-longstop-linker-neo-longstop-Kras*G12D-FLAG-AID-EGFP-ALFA-tag-Wpre-pA expression cassette was knocked into the R26 locus.
R26-CAG-neo-longstop-linker-neo-longstop-FLAG-AID-EGFP-ALFA-tagKIOverexpression, Fluorescent ModelDEVELOPINGKI 234476Inquire
The CAG-neo-longstop-linker-neo-longstop-FLAG-AID-EGFP-ALFA-tag-Wpre-pA expression cassette was knocked into the R26 locus.
R26-mU6-gRNA(Tyr)1-mU6-gRNA(Tyr)2-CAG-Cas9KIOverexpressionDEVELOPINGKI 234337Inquire
The mU6-gRNA(Tyr)1-mU6-gRNA(Tyr)2-Ins-CAG-Cas9-WPRE-polyA expression cassette was knocked into the R26 locus.
R26-U6-gRNA(Tgm3)1-U6-gRNA(Tgm3)2-CAG-Cas9KIOverexpressionDEVELOPINGKI 234336Inquire
The U6-gRNA(Tgm3)1-U6-gRNA(Tgm3)2-Ins-CAG-Cas9-WPRE-polyA expression cassette was knocked into the R26 locus.
R26-loxp2217-mU6-gRNA(lep)1-mU6-gRNA(lep)2-loxp-CAG-Cas9KIOverexpressionDEVELOPINGKI 234335Inquire
The loxp2217-mU6-gRNA(lep)1-mU6-gRNA(lep)2-loxp-Ins-CAG-Cas9-WPRE-polyA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-MRGPRX4KIOverexpression, Target-HumanizedSPERMKI 234360Inquire
The SA-FRT-2xpA-CAG-FRT-LSL-Kozak-MRGPRX4-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-hTSHRa(BALB/c)KIOverexpression, Target-HumanizedSPERMKI 234654Inquire
The CAG-loxP-STOP-lox2272-hTSHRa-loxP-lox2272-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-APEX2-Linker1-3xHA-Linker1-3c-Linker1-3xMyc-Linker2-Map1lc3b (CDS+3'UTR)KIOverexpressionSPERMKI 234893Inquire
The CAG-LSL-Kozak-APEX2-Linker1-3xHA-Linker1-3c-Linker1-3xMyc-Linker2-Map1lc3b (CDS+3'UTR)-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-ITK-SYK-IRES-EGFPKIOverexpression, Fluorescent ModelSPERMKI 240829Inquire
The SA-FRT-2xpA-CAG-FRT-LSL-ITK-SYK-IRES-EGFP-WPRE-pA expression cassette was knocked into the R26 locus.
R26-nTnGKIOverexpression, Fluorescent ModelSPERMKI 240767Inquire
The CAG-loxP-H2B-tdTomato-pA-loxP-H2B-eGFP-pA expression cassette was knocked into the R26 locus.
R26-CAG-MYOC mutant-3xFlag-linker-3xHAKIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)SPERMKI 240582Inquire
The CAG-MYOC mutant-3xFlag-linker-3xHA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-KikGRKIOverexpression, Fluorescent ModelLIVEKI 240597Inquire
The CAG-LSL-Kozak-KikGR-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-OsTIR1(F74G)-3xFLAGKIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)SPERMKI 240363Inquire
The CAG-LSL-Kozak-OsTIR1(F74G)-3xFLAG-WPRE-polyA expression cassette was knocked into the R26 locus.
R26-SA-CAG-LSL-HHLA2KIOverexpression, Target-HumanizedSPERMKI 240341Inquire
The SA-FRT-2xpA-CAG-FRT-LSL-HHLA2-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-Arl13b-Linker-mCherry-CAG-LSL-EGFP-CETN2KIOverexpression, Fluorescent ModelSPERMKI 241383Inquire
The CAG-LSL-Kozak-Arl13b-Linker-mCherry-WPRE-pA-CAG-lox2272-STOP-lox2272-Kozak-EGFP-CETN2-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-Usp13KIOverexpressionSPERMKI 241264Inquire
The CAG-loxP-STOP-loxP-Usp13-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-sfGFP-KASHKIOverexpression, Fluorescent ModelSPERMKI 241231Inquire
The CAG-LSL-Koazk-superfolder GFP-KASH-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-Cxcl13KIOverexpressionSPERMKI 241879Inquire
The CAG-loxP-STOP-loxP-Cxcl13-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-SLIT3*R1479CKIPoint Mutation, OverexpressionSPERMKI 225092Inquire
CAG-LSL-SLIT3*R1479C-WPRE-pA expression cassette was knocked into the Rosa26 locus.
R26-CAG-LSL-RSR-DTAKIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)SPERMKI 225080Inquire
CAG-LSL-RSR-DTA-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-IL37KIOverexpressionSPERMKI 225079Inquire
CAG-LSL-IL37-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-MetrnlKIOverexpressionSPERMKI 225077Inquire
CAG-Metrnl-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-PhiC31-ERT2KIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)SPERMKI 230051Inquire
CAG-Loxp-STOP-Loxp-PhiC31-ERT2-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-SA-LSL-hMycRTG3-ERT2-IRES-EGFPKIOverexpression, Fluorescent Model, Target-HumanizedSPERMKI 225096Inquire
SA-loxp-stop-loxp-hMycRTG3-ERT2-IRES-EGFP-WPRE-pA expression cassette was knocked into the Rosa26 locus.
R26-SA-Loxp-PGK-Neo-Loxp-Pik3ca-H1047RKIPoint Mutation, Overexpression, Disease ModelLIVEKI 225095Inquire
SA-Loxp-PGK-Neo-pA-Loxp-Pik3ca-H1047R-pA expression cassette was knocked into the Rosa26 locus.
R26-LSL-hIGF1R-IRES-EGFPKIOverexpression, Fluorescent Model, Target-HumanizedSPERMKI 231795Inquire
The CAG-LSL-Kozak-hIGF1R-IRES-EGFP-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-hFCGR3A-IRES-tdTomatoKIOverexpression, Fluorescent Model, Target-HumanizedEMBRYOKI 200255Inquire
A SA-FRT-2xpolyA-CAG-FRT-loxp-stop-loxp-FCGR3A-IRES-tdTomato-WPRE-polyA expression cassette was knocked into the Rosa26 locus via CRISPR/Cas9 mediated recombination.
R26-CAG-LSL-OsTir1-9xMycKIOverexpressionSPERMKI 220389Inquire
CAG-loxP-STOP-loxP-Kozak-OsTir1-9xMyc-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-PpdpfKIOverexpressionSPERMKI 234713Inquire
The CAG-loxP-STOP-loxP-Kozak-Ppdpf-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-Cpf1-IRES-EGFPKIOverexpression, Fluorescent ModelSPERMKI 234699Inquire
The CAG-loxP-Neo-STOP-Neo-STOP-loxP-Kozak-Cpf1-IRES-EGFP-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-Trp53-IRES-EGFPKIOverexpression, Fluorescent ModelSPERMKI 234413Inquire
The CAG-LSL-Trp53-IRES-EGFP-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-EML4-ALK-IRES-Luc-2A-TdtomatoKIOverexpression, Fluorescent ModelSPERMKI 225040Inquire
CAG-FRT-loxp-stop-loxp-EML4-ALK-IRES-Luciferase-2A-Tdtomato-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Trim11KIOverexpressionSPERMKI 233701Inquire
The CAG-LSL-Kozak-Trim11-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-hEGFRvIII-IRES-LucKIOverexpression, Fluorescent Model, Target-HumanizedSPERMKI 233898Inquire
The CAG-LSL-Kozak-hEGFRvIII-IRES-Luc-WPRE-pA expression cassette was knocked into the R26 locus.
R26-LSL-hNTN1KIOverexpression, Target-HumanizedSPERMKI 233967Inquire
The SA-LSL-Kozak-hNTN1-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-loxP-RSR-loxP-STOP-rox-DTAKIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)SPERMKI 233974Inquire
The CAG-loxP-rox-STOP-rox-loxP-STOP-rox-DTA-WPRE-pA expression cassette was knocked into the R26 locus.
R26-rtTAKIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)SPERMKI 232260Inquire
The CAG-M2rtTA-WPRE-pA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-Hif3aKIOverexpressionSPERMKI 233049Inquire
The CAG-LSL-Hif3a-WPRE-pA expression cassette was knocked into the R26 locus.
R26-PGK-Puro-polyAKIOverexpressionSPERMKI 232839Inquire
The PGK-Puro-polyA-PGK-Puro-polyA-PGK-Puro-polyA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-Il33-IRES-tdTomatoKIOverexpression, Fluorescent ModelEMBRYOKI 200053Inquire
These mice harbor a SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-Il33-IRES-tdTomato -WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-U6-Luc3.12 gRNA-CAG-Cas13bKIOverexpression, Fluorescent ModelSPERMKI 200264Inquire
These mice harbor a U6-Luc3.12 gRNA-CAG-Cas13b cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-Armc12-IRES-tdTomatoKIOverexpression, Fluorescent ModelEMBRYOKI 200290Inquire
A CAG-LSL-Armc12-IRES-tdTomato-Wpre-pA expression cassette was knocked into the Rosa26 locus via CRISPR/Cas9 mediated recombination.
R26-CAG-LSL-Tgfa-IRES-Luc-2A-EGFPKIOverexpression, Fluorescent Model, Disease ModelEMBRYOKI 200038Inquire
These mice harbor a SA-Frt-2xpA-CAG-Frt-LSL-Tgfa-IRES-Luc-2A-EGFP-Wpre-pA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hCD63-copGFPKIOverexpression, Fluorescent Model, Target-HumanizedSPERMKI 200044Inquire
These mice harbor a pCAG-FRT-loxp-stop-loxp-hCD63-copGFP-6xHis-WPRE-polyA-FRT cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-DreERT2KIOverexpression, Cre/Dre ToolboxSPERMKI 200040Inquire
These mice harbor a SA-FRT-2xpolyA-CAG-FRT-DreERT2-Rox-WPRE-Rox-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-loxP-tdTomato-loxP-DTAKIOverexpression, Fluorescent ModelLIVEKI 225003Inquire
SA-loxP-tdTomato-PGK-Neo-3xpA-loxP-DTA-pA expression cassette was knocked into the the Rosa26 locus.
R26-ZsGreen-DTAKIOverexpression, Fluorescent ModelLIVEKI 225002Inquire
CAG-zsGreen-DTA expression cassette was knocked into the the Rosa26 locus.
R26-CreERT2(2)KIOverexpression, Cre/Dre ToolboxSPERMKI 220020Inquire
SA-FRT-CreERT2-Rox-WPRE-Rox-polyA expression cassette was knocked into the the Rosa26 locus. While R26-CreERT2(Stock No.KI 200041) mice function similarly to R26-CreERT2(2) mice,for more detailed information please contact our technical advisor.
R26-CAG-LSL-PyMT-IRES-Luc-2A-EGFPKIOverexpression, Fluorescent ModelEMBRYOKI 190111Inquire
These mice harbor a CAG-LSL-PyMT-IRES-Luc-2A-EGFP-Wpre-pA conditional expression cassette in mouse Rosa26 loci via CRISPR/Cas mediated homologous recombination.
R26-CAG-LSL-hMLL-AF9-IRES-Luc-2A-tdTomatoKIOverexpression, Fluorescent Model, Target-Humanized, Disease ModelEMBRYOKI 190114Inquire
These mice harbor a SA-Frt-pA-CAG-Frt-LSL-MLL-AF9-IRES-Luc-2A-tdTomato-WPRE-pA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hSOS-F-tdTomatoKIOverexpression, Fluorescent Model, Target-Humanized, Disease ModelEMBRYOKI 200020Inquire
These mice harbor a SA-FRT-2xpolyA-CAG-FRT-loxp-Stop-loxp-SOS-F-IRES-tdTomato-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-Resp18-IRES-tdTomatoKIOverexpression, Fluorescent ModelSPERMKI 200270Inquire
CAG-LSL-Resp18-IRES-tdTomato-WPRE-polyA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-hSOD1*G94A-IRES-EGFPKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelSPERMKI 200263Inquire
A CAG-FRT-LSL- SOD1(G94A)-IRES-EGFP-WPRE-pA expression cassette was knocked into the Rosa26 locus.
R26-CAG-LSL-Kdm7a-2A-tdTomatoKIOverexpression, Fluorescent ModelLIVEKI 200297Inquire
A CAG-LSL-Kdm7a-2A-tdTomato-Wpre-pA expression cassette was knocked into the Rosa26 locus.
R26-LSL-Atad3a-IRES-tdTomatoKIOverexpression, Fluorescent ModelSPERMKI 225045Inquire
LSL-Atad3a-IRES-tdTomato expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-OVA-Luc-IRES-tdTomatoKIOverexpression, Fluorescent ModelSPERMKI 200230Inquire
These mice harbor a SA-FRT-2xpolyA-CAG-FRT-loxp-stop-loxp-OVA-IRES-Luciferase-2A-tdTomato-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hFCGR2A-IRES-EGFPKIOverexpression, Fluorescent Model, Target-HumanizedEMBRYOKI 200229Inquire
These mice harbor a SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-FCGR2A-IRES-EGFP-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-U6-mcherry gRNA-CAG-Cas13dKIOverexpression, Fluorescent ModelEMBRYOKI 200268Inquire
These mice harbor a U6-mcherry gRNA-CAG-Cas13d cassette in the Rosa26 locus generated by homologous recombination.
R26-U6-mcherry gRNA-CAG-Cas13bKIOverexpression, Fluorescent ModelSPERMKI 200266Inquire
These mice harbor a U6-mcherry gRNA-CAG-Cas13b cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hFGFR2-IRES-Luc-2A-EGFPKIOverexpression, Fluorescent Model, Target-Humanized, Disease ModelEMBRYOKI 190007Inquire
A SA-2xpolyA-CAG-LSL-FGFR2-IRES-luciferase-2A-EGFP-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the FGFR2 protein.
R26-LSL-Luc-2A-tdTomatoKIOverexpression, Fluorescent ModelSPERMKI 225044Inquire
LSL-Luciferase-2A-tdTomato expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Cas13d-IRES-tdTomatoKIOverexpression, Fluorescent ModelSPERMKI 190063Inquire
These mice harbor a CAG-LSL-Cas13d-IRES-tdTomato cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-Ythdf3-IRES-EGFPKIOverexpression, Fluorescent ModelEMBRYOKI 190062Inquire
These mice harbor a CAG-LSL-3xFLAG-Ythdf3-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-Ythdc1-IRES-EGFPKIOverexpression, Fluorescent ModelEMBRYOKI 190059Inquire
These mice harbor a CAG-LSL-Ythdc1-3xFLAG-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination.
R26-LSL-CD3e-VL1-IRES-EGFPKIOverexpression, Fluorescent ModelSPERMKI 190100Inquire
These mice harbor a SA-LSL-CD3e-VL1-IRES-EGFP-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hTPM3-NTRK1-IRES-Luc-2A-tdTomatoKIOverexpression, Fluorescent Model, Target-Humanized, Disease ModelSPERMKI 190098Inquire
These mice harbor a SA-polyA-CAG-LSL-TPM3-NTRK1-IRES-luc-2A-tdTomato-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-dCas9-IRES-EGFPKIOverexpression, Fluorescent ModelEMBRYOKI 18031Inquire
A CAG promoter-loxp-stop-loxp-Avi tag-dCas9-IRES-EGFP-WPRE-polyA expression cassette was inserted at the Rosa26 locus site.
R26-LSL-CD3e-VL2-IRES-EGFPKIOverexpression, Fluorescent ModelSPERMKI 190108Inquire
These mice harbor a SA-loxp-STOP-loxp-CD3e-VL2-IRES-EGFP- WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hETV6/NTRK3-IRES-Luc-2A-tdTomatoKIOverexpression, Fluorescent Model, Target-HumanizedSPERMKI 190107Inquire
These mice harbor a SA-polyA-CAG-LSL-ETV6-NTRK3-IRES-luc-2A-tdTomato-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-zsGreen-tdTomatoKIOverexpression, Fluorescent ModelSPERMKI 225043Inquire
CAG-FRT-zsGreen-FRT-tdTomato expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-ChR2-H134R-tdTomatoKIPoint Mutation, Overexpression, Fluorescent ModelLIVEKI 190113Inquire
These mice harbor a CAG-LSL-chR2(H134R)-tdTomato-WPRE-pA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-Tlr4KIOverexpressionEMBRYOKI 190112Inquire
These mice harbor a CAG-LSL-Tlr4-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-EGFP(2)KIOverexpression, Fluorescent ModelSPERMKI 190089Inquire
These mice harbor a CAG-EGFP-WPRE-polyA cassette in the Rosa26 locus.1 generated by homologous recombination. While R26-CAG-EGFP(Stock No.KI 190088) and R26-CAG-EGFP(3)(Stock No.KI 190090) function similarly to R26-CAG-EGFP(2) mice,for more detailed information please contact our technical advisor.
R26-CAG-EGFPKIOverexpression, Fluorescent ModelSPERMKI 190088Inquire
These mice harbor a SA-2xpA-CAG-EGFP-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. While R26-CAG-EGFP(2)(Stock No.KI 190089) and R26-CAG-EGFP(3)(Stock No.KI 190090) function similarly to R26-CAG-EGFP mice,for more detailed information please contact our technical advisor.
R26-CAG-LSL-Virma-IRES-EGFPKIOverexpression, Fluorescent ModelSPERMKI 190057Inquire
These mice harbor a CAG-LSL-Virma-3xFLAG-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-Mettl3-IRES-EGFPKIOverexpression, Fluorescent ModelSPERMKI 190056Inquire
These mice harbor a CAG-LSL-3xFLAG-Mettl3-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-Fto-IRES-EGFPKIOverexpression, Fluorescent Model, Disease ModelEMBRYOKI 190055Inquire
These mice harbor a CAG-LSL-3xFLAG-Fto-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hIDH2*R172K-IRES-Luci-2A-tdTomatoKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelSPERMKI 190076Inquire
These mice harbor a CAG-LSL-IDH2(R172K)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hFGFR2*S320C-IRES-Luc-2A-EGFPKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelEMBRYOKI 190079Inquire
These mice harbor a CAG-LSL-FGFR2(S320C)-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hFGFR3*S249C-IRES-Luc-2A-EGFPKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelEMBRYOKI 190082Inquire
These mice harbor a CAG-LSL-FGFR3(S249C)-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hFGFR3*K562E-IRES-Luc-2A-EGFPKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelEMBRYOKI 190081Inquire
These mice harbor a CAG-LSL-FGFR3(K562E)-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination.
R26-RNR-GFPDTRKIOverexpression, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent)SPERMKI 18013Inquire
These mice harbor a SA-Rox-Neo-Rox-GFPDTR-Frt-Wpre-Frt-pA expression cassette in mouse Rosa26 loci via homologous recombination.
R26-CAG-2xKRAB-dCas9-IRES-EGFPKIOverexpression, Fluorescent ModelLIVEKI 18007Inquire
These mice harbor a CAG-LSL-2xKRAB-dCas9-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via homologous recombination. This strain can be used in CRISPR mediated target gene transcriptional inhibition (CRISPRi). The loxp-stop-loxp cassette was deleted.
R26-LSL-PhiC31KIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)SPERMKI 00088Inquire
These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven PhiC31 gene. The targeted mutation was inserted into the Gt(ROSA)26Sor locus.
R26-CAG-Luc-2A-EGFPKIOverexpression, Fluorescent ModelLIVEKI 00087Inquire
This R26-(CAG-Luc-EGFP) strain was generated by crossing R26-(CAG-LSL-Luc-EGFP)(KI 190095) mice with Ddx4-Cre mice.
R26-CAG-LSL-hNRF2-IRES-Luc-2A-tdTomatoKIOverexpression, Fluorescent Model, Target-HumanizedSPERMKI 18050Inquire
A SA-2xpolyA-CAG-LSL-human NRF2-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus . This strain of mice can be mated with mice expressing Cre recombinase to express human NRF2 and a reporter gene in certain cells or tissues that expressing Cre recombinase.
R26-CAG-LSL-tdTomatoKIOverexpression, Fluorescent ModelSPERMKI 225042Inquire
CAG-LSL-tdTomato expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Itpr1-tdTomatoKIOverexpression, Fluorescent ModelEMBRYOKI 18046Inquire
These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Itpr1-3xFlag-IRES-tdTomato expression cassette. The targeted mutation was inserted into the Gt(ROSA)26Sor locus.
R26-CAG-LSL-hEGFR*T790M-IRES-Luc-2A-tdTomatoKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelSPERMKI 190070Inquire
These mice harbor a CAG-LSL-EGFR(T790M)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-Clover-Geminin(1-110)-2A-mKO2-Cdt(30-120)KIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)EMBRYOKI 200008Inquire
These mice harbor a SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-Clover-Geminin(1-110)-P2A-mKO2-Cdt(30-120)-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-mTurquoise2-SLBP(18-126)-2A-H1-mMaroon1KIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)EMBRYOKI 200007Inquire
These mice harbor a SA-Frt-2xpolyA-CAG-Frt-LSL-mTurquoise2-SLBP(18-126)-P2A-H1-mMaroon1-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-TetO-Dre-IRES-mtagBFP2KIOverexpression, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent)LIVEKI 190020Inquire
The SA-polyA-Ins-Ins-TetO-Dre-IRES-BFP-polyA-Ins-Ins cassette is inserted in mouse Rosa26 loci.
R26-CAG-LSL-Ythdf2-IRES-EGFPKIOverexpression, Fluorescent ModelSPERMKI 190018Inquire
These mice harbor a SA-2xpolyA-CAG-LSL-3xFLAG-Ythdf2-IRES-EGFP-Wpre-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hREST4-IRES-EGFPKIOverexpression, Fluorescent Model, Target-HumanizedSPERMKI 200052Inquire
These mice harbor a CAG-LSL-REST4-IRES-EGFP-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hREST-IRES-tdTomatoKIOverexpression, Fluorescent Model, Target-HumanizedEMBRYOKI 200051Inquire
These mice harbor a CAG-LSL-REST-IRES-tdTomato-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hMYCN-IRES-BFPKIOverexpression, Fluorescent Model, Target-HumanizedSPERMKI 225000Inquire
CAG-LSL-HA-MYCN-IRES-BFP-Wpre-polyA expression cassette was knocked into the the Rosa26 locus.
R26-LSL-hIL15-Flag-IRES-EGFPKIOverexpression, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent), Target-HumanizedSPERMKI 220130Inquire
CAG-Loxp-Stop-Loxp-Kozak-hIL2 signal peptide-hIL15-Flag-IRES-EGFP-polyA expression cassette was knocked into the the Rosa26 locus
R26-LNL-PBKIOverexpressionSPERMKI 00065Inquire
These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven piggyBac transposase. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination. PiggyBac transposase is expressed when bred to mice that express Cre recombinase.
R26-CAG-LSL-hWNT1KIOverexpression, Target-Humanized, Disease ModelSPERMKI 190128Inquire
These mice harbor a SA-Frt-2xpA-CAG-Frt-LSL-WNT1-IRES-Luc-2A-tdTomato-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hBCR/ABLKIOverexpression, Target-Humanized, Disease ModelSPERMKI 190127Inquire
These mice harbor a CAG-LSL-BCR-ABL-IRES-Luciferase-2A-tdTomato-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hPNPLA3-I148M-EGFPKIOverexpression, Fluorescent Model, Target-HumanizedLIVEKI 200013Inquire
These mice harbor a SA-Frt-2xpolyA-CAG-Frt-LSL-hPNPLA3 I148M-IRES-GFP-wpre-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hTARDBP*A315T-EGFPKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelSPERMKI 200019Inquire
These mice harbor a CAG-LSL-3xFlag-TARDBP(A315T)-IRES-GFP-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-DreKIOverexpression, Cre/Dre ToolboxSPERMKI 200042Inquire
These mice harbor a CAG-Dre-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hDSG2KIOverexpression, Target-HumanizedSPERMKI 210444Inquire
CAG-LSL-hDSG2-WPRE-pA expression cassette was knocked into the Rosa26 locus.
R26-CreERT2KIOverexpression, Cre/Dre ToolboxLIVEKI 200041Inquire
These mice harbor a SA-FRT-2xpolyA-CAG-FRT-CreERT2-Rox-WPRE-Rox-polyA cassette in the Rosa26 locus generated by homologous recombination. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in multiple tissues after tamoxifen treatment.
R26-CAG-LSL-Trem2KIOverexpressionSPERMKI 215105Inquire
CAG-Loxp-Stop-Loxp-Trem2-Wpre-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Mdfi-2A-EGFPKIOverexpression, Fluorescent ModelEMBRYOKI 215104Inquire
CAG-Loxp-Stop-Loxp-Kozak-Mdfi-P2A-GFP-bGH-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-hAR-IRES-EGFPKIOverexpression, Fluorescent Model, Target-HumanizedSPERMKI 215053Inquire
R26-CAG-Loxp-Stop-Loxp-hAR-IRES-EGFP-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-FCGR3A-IRES-tdTomatoKIOverexpression, Fluorescent ModelSPERMKI 215052Inquire
SA-FRT-2xpolyA-CAG-FRT-loxp-stop-loxp-FCGR3A-IRES-tdTomato-WPRE-polyA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Coro1aKIOverexpressionEMBRYOKI 215009Inquire
A CAG-LSL-Coro1a-linker-3xFlag-HA-WPRE-pA expression cassette was knocked into the Rosa26 locus.
R26-CAG-LSL-jGCaMP7fKIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)LIVEKI 215003Inquire
A CAG-LSL-jGCaMP7f-WPRE-pA expression cassette was knocked into the Rosa26 locus.
R26-CAG-LSL-hPLAG1-IRES-Luc-2A-tdTomatoKIOverexpression, Fluorescent Model, Target-HumanizedSPERMKI 215002Inquire
A CAG-LSL-hPLAG1-IRES-Luciferase-2A-tdTomato-wpre-polyA expression cassette was knocked into the Rosa26 locus.
R26-CAG-LSL-jRGECO1aKIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)SPERMKI 215001Inquire
A CAG-LSL-jRGECO1a-pA expression cassette was knocked into the Rosa26 locus.
R26-CAG-LSL-SoNarKIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)SPERMKI 215000Inquire
A CAG-LSL-SoNar-WPRE-polyA expression cassette was knocked into the Rosa26 locus.
R26-CAG-mEGFP-2A-paAIP2KIOverexpression, Fluorescent ModelEMBRYOKI 200315Inquire
A CAG-mEGFP-2A-paAIP2-Wpre-pA expression cassette was knocked into the Rosa26 locus.
R26-CAG-LSL-mutant Ccnc-HAKIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)EMBRYOKI 210005Inquire
A CAG-LSL-mutant Ccnc-HA-Wpre-pA expression cassette was knocked into via.
R26-CAG-LSL-Gpld1-IRES-tdTomatoKIOverexpression, Fluorescent ModelEMBRYOKI 210004Inquire
A CAG-LSL-Gpld1-IRES-tdTomato-Wpre-pA expression cassette was knocked into via.
R26-CAG-LSL-Kras*G12C-IRES-Luc(BALB/c)KIPoint Mutation, Overexpression, Fluorescent Model, Disease ModelSPERMKI 200324Inquire
A CAG-FRT-loxp-stop-loxp-Kras(G12C)-IRES-Luciferase-polyA expression cassette was knocked into the R26 locus via CRISPR/Cas9 mediated recombination.
R26-CAG-LSL-hCD2*C truncatedKIOverexpression, Target-HumanizedEMBRYOKI 200321Inquire
A CAG-LSL-hCD2 C truncated-WPRE-polyA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-hSNCA*A53T-IRES-EGFPKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelSPERMKI 200320Inquire
A CAG-LSL-SNCA A53T-IRES-EGFP-WPRE-polyA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-SOX2-IRES-Luc-2A-EGFPKIOverexpression, Fluorescent ModelSPERMKI 210138Inquire
A CAG-LSL-SOX2-IRES-Luciferase-2a-EGFP-WPRE-polyA expression cassette was knocked into via the Rosa26 locus.
R26-CAG-LSL-hSIGLEC8-IRES-EGFPKIOverexpression, Fluorescent Model, Target-HumanizedEMBRYOKI 210137Inquire
A CAG-LSL-SIGLEC8-IRES-EGFP-WPRE-polyA expression cassette was knocked into via the Rosa26 locus.
R26-CAG-LSL-CAMK2GKIOverexpressionSPERMKI 220326Inquire
CAG-loxP-STOP-loxP-CAMK2G-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-Fkbp8-IRES-EGFPKIOverexpression, Fluorescent ModelSPERMKI 210135Inquire
A CAG-LSL-Fkbp8-IRES-EGFP-WPRE-polyA expression cassette was knocked into via the Rosa26 locus.
R26-CAG-LSL-Avi-GFP-Rpl10aKIOverexpression, Fluorescent ModelSPERMKI 210142Inquire
A SA-2xpolyA-CAG-LSL-Avitag-GFP-Rpl10a-WPRE-polyA expression cassette was knocked into via the Rosa26 locus.
R26-CAG-LSL-hACE2-IRES-tdTomatoKIOverexpression, Fluorescent Model, Target-Humanized, Disease ModelSPERMKI 200188Inquire
These mice harbor a SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyAA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-LucKIOverexpression, Fluorescent Model, Disease ModelEMBRYOKI 200257Inquire
A CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luciferase expression cassette was knocked into the Rosa26 locus.
R26-LSL-SmoM2W539L-IRES-tdTomatoKIOverexpression, Fluorescent Model, Disease ModelEMBRYOKI 200035Inquire
These mice harbor a SA-loxp-stop-loxp-SmoM2(W539L)-IRES-tdTomato-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. W539L point mutation of the mouse gene (SmoM2), which corresponds to the W535L mutation in the human sequence.
R26-CAG-LSL-zsGreenKIOverexpression, Fluorescent Model, Disease ModelLIVEKI 200045Inquire
These mice harbor a CAG-LSL-zsGreen-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-U6-Luc3.12 gRNA-CAG-Cas13dKIOverexpression, Fluorescent ModelEMBRYOKI 200265Inquire
These mice harbor a U6-Luc3.12 gRNA-CAG-Cas13d cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-loxp-tdTomato-loxp2272-Tag-IRES-EGFP-2A-Luc-loxp-loxp2272KIOverexpression, Fluorescent Model, Disease ModelEMBRYOKI 200033Inquire
These mice harbor a SA-FRT-2xpolyA-CAG-FRT-loxp-tdTomato-polyA-loxp2272-polyA-Wpre-Tag-IRES-EGFP-2A-Luciferase-loxp-loxp2272 cassette in the Rosa26 locus generated by homologous recombination.
R26-pAPOE-hCYP3A4(FVB)KIOverexpression, Target-HumanizedEMBRYOKI 18032Inquire
This knock-in model was generated by inserting the human CYP3A4 cDNA driven by the liver-specific APOE promoter into the mouse Rosa26 site, which can be used to obtain liver-expressed CYP3A4 humanized model after mating with the Cyp3a13 gene and other Cyp3a family gene knockout mice. This model can be used with KI 18033 mice which has gut-specific expression of human CYP3A4 to compare the contribution of intestinal versus hepatic metabolism to the biotransformation of a test article.
R26-CAG-LSL-hEML4/ALK-IRES-Luc-2A-tdTomatoKIOverexpression, Fluorescent Model, Target-Humanized, Disease ModelSPERMKI 190072Inquire
These mice harbor a CAG-LSL-EML4-ALK-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.Please check if the EML4-ALK fusion variant is what you need before ordering.
R26-CAG-LSL-hFGFR2*W290C-IRES-Luc-2A-EGFPKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelEMBRYOKI 190080Inquire
These mice harbor a CAG-LSL-FGFR2(W290C)-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hFGFR2*K659N-IRES-Luc-2A-EGFPKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelEMBRYOKI 190078Inquire
These mice harbor a CAG-LSL-FGFR2(K659N)-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hIDH2*R140Q-IRES-Luc-2A-tdTomatoKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelEMBRYOKI 190075Inquire
These mice harbor a CAG-LSL-IDH2(R140Q)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hIDH1*R132H-IRES-Luc-2A-tdTomatoKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelEMBRYOKI 190074Inquire
These mice harbor a CAG-LSL-IDH1(R132H)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hFGFR3-IRES-Luc-2A-EGFPKIOverexpression, Fluorescent Model, Target-Humanized, Disease ModelEMBRYOKI 190083Inquire
These mice harbor a CAG-LSL-FGFR3-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-hHER2-IRES-Luc-2A-EGFPKIOverexpression, Fluorescent Model, Target-Humanized, Disease ModelSPERMKI 190008Inquire
A SA-2xpolyA-CAG-LSL-HER2-IRES-Luciferase-2A-EGFP-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the HER2 protein.
R26-CAG-LSL-hMET-IRES-Luc-2A-tdTomatoKIOverexpression, Fluorescent Model, Target-Humanized, Disease ModelSPERMKI 18052Inquire
A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human cMET-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that human C-MET could be expressed after exposure to Cre recombinase.
R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc/Krt14-CreERT2KIOverexpression, Cre/Dre Toolbox, Fluorescent ModelLIVEKI 234663Inquire
The R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc(KI 200257) was crossed with Krt14-CreERT2(KI 190024) to generate R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc/Krt14-CreERT2 mice.
R26-pVillin1-hCYP3A4-IRES-tdTomato(FVB)KIOverexpression, Fluorescent Model, Target-HumanizedEMBRYOKI 18033Inquire
Intestinal expression of the CYP3A enzyme in the human body can cause significant intestinal metabolism of the compound, resulting in impaired drug absorption. This knock-in model was generated by inserting the human CYP3A4 cDNA driven by the Villin1 promoter together with the IRES-tdTomato reporter gene into mosue Rosa26 site, which can be crossed with the Cyp3a13 gene knockout and other Cyp3a family genes knockout mice to obtain intestinal-expressed CYP3A4 humanized mouse model in order to determine the contribution of intestinal metabolism to the absorption and distribution of test article.
R26-Renilla-LucKIOverexpression, Fluorescent ModelEMBRYOKI 00091Inquire
These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Renilla-Luc gene. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination.
R26-CAG-LNL-CaMPARIKIOverexpression, Fluorescent ModelEMBRYOKI 00090Inquire
These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven CaMPARI gene. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination.
R26-CAG-hFcRnKIOverexpression, Target-HumanizedEMBRYOKI 00081Inquire
A human FCGRT expression cassette was knocked in mouse Rosa26 loci.
R26-U6-gRNA-Apoe-LdlrKIOverexpressionEMBRYOKI 18005Inquire
These mice harbor an U6-gRNA-Apoe-Ldlr cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-dCas9-VPR-IRES-EGFPKIOverexpression, Fluorescent ModelLIVEKI 18004Inquire
These mice harbor a CAG-LSL-dCas9-VPR(VP64-p65-Rta)-eGFP-pA conditional expression cassette in mouse Rosa26 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).
R26-SA-BirAKIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)EMBRYOKI 00085Inquire
A SA-BirA-polyA expression cassette was knocked in mouse Rosa26 loci . Heterozygous knockin mice developed normally.
R26-CAG-LNL-Fen1-IRES-EGFPKIOverexpression, Fluorescent ModelEMBRYOKI 00126Inquire
These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Fen1 gene followed by 3xHA-IRES-EGFP tag coexpression cassette. The targeted mutation was inserted into the Rosa26 locus by homologous recombination.
R26-CAG-LSL-NgAgo-IRES-EGFPKIOverexpression, Fluorescent ModelEMBRYOKI 18011Inquire
These mice harbor a CAG-LSL-NgAgo-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via homologous recombination.
R26-hCD46-IRES-tdTomatoKIOverexpression, Fluorescent Model, Target-Humanized, Disease ModelEMBRYOKI 190087Inquire
These mice harbor a SA-human CD46-IRES-tdTomato-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-Luc-2A-EGFPKIOverexpression, Fluorescent ModelLIVEKI 190095Inquire
A CAG-LSL-Luciferase-2A-EGFP-wpre-polyA expression cassette was inserted at the Rosa26 locus site.
R26-CAG-LSL-2xKRAB-dCas9-IRES-EGFPKIOverexpression, Fluorescent ModelLIVEKI 220013Inquire
CAG-Loxp-Stop-Loxp-2xKRAB-dCas9-IRES-EGFP-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
R26-CAG-LSL-tdTomato-2A-DTRKIOverexpression, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent)LIVEKI 210094Inquire
These mice harbor a CAG-LSL-R-tdTomato-2A-DTR cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LSL-Kras*G12C-IRES-LucKIPoint Mutation, Overexpression, Fluorescent Model, Disease ModelLIVEKI 200323Inquire
A CAG-FRT-loxp-stop-loxp-Kras(G12C)-IRES-Luciferase-polyA expression cassette was knocked into the R26 locus.
R26-CAG-LSL-hTM6SF2*E167K-EGFPKIPoint Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease ModelEMBRYOKI 200017Inquire
These mice harbor a SA-Frt-2xpolyA-CAG-Frt-LSL-TM6SF2-IRES-GFP-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.
R26-CAG-LNL-ddCas9KIOverexpression, Other Toolbox (non-Cre, non-Fluorescent)EMBRYOKI 00063Inquire
These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven ddCas9. The targeted mutation was inserted into the Gt(ROSA)26Sor locus.
R26-CAG-LNL-Hmgb2KIOverexpressionEMBRYOKI 190130Inquire
These mice harbor a CAG-LNL-Hmgb2-3xFlag-Wpre-polyA cassette in the Rosa26 locus generated by homologous recombination.
R26-SA-LNL-C1qtnf1KIOverexpressionEMBRYOKI 190129Inquire
These mice harbor a SA-Loxp-Neo-polyA-Loxp-C1qtnf1-polyA cassette in the Rosa26 locus generated by homologous recombination.

Why this approach

Knockin and humanized formats keep regulatory context at the endogenous locus. For your target tissue focused programs, that matters when expression timing, splice isoforms, or allele dosage drive biology. Random integration transgenics can still help, but targeted alleles usually give cleaner pharmacology readouts.

Pricing and quotes

The R26 Knockin lines listed above are catalog models. Send us the catalog number and our team confirms current availability, pricing, and whether the line ships cryopreserved or live.

If your study needs a R26 allele configuration that is not listed above, our scientific team designs and generates it. Model generation quotes return in about twenty four hours with project milestones and pricing.

Order a catalog R26 modelRequest a model generation quote

FAQ

What R26 Knockin mouse models are available?

When R26 Knockin lines are in catalog, we ship from inventory. If your configuration is not listed, we design the allele to order. Common paths include conditional knockout, constitutive knockout, humanized, knockin, and transgenic options, with documented germline transmission and United States QC.

Is R26 knockout embryonic lethal in mice?

It depends on background and allele design. Some R26 germline knockouts are viable. Others need conditional alleles or mixed backgrounds. We review publications and our own experience, then recommend floxed versus null before you commit.

Which Cre driver is best for experiments?

Driver choice depends on onset timing, recombination efficiency, and known leak. We map your organ and cell type to a short list of proven Cre lines, then talk through reporter crosses and controls. We favor drivers with strong community validation for your tissue.

Do you ship live R26 animals?

When catalog lines are live, we ship with health certificates and QC documentation. If your exact combo is not listed, we quote a generation project with cryo or live dispatch depending on cohort timing and geography.

How do I request a quote for R26?

Use the catalog inquire buttons or the request quote form. Include your allele goal, Cre plan if any, strain background, and cohort size. A PhD led team responds with pricing, milestones, and the fastest path to experimental animals.

Related models and routes

All R26 models

Breed this line with ingenious targeting laboratory

Send the R26 Knockin line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.