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R26 Knockin mouse models
Knockin designs at R26 support head to head comparisons between wild type and modified alleles because regulatory DNA stays in place.
What R26 Knockin mouse models are available?
ingenious targeting laboratory offers 298 distinct R26 knockin catalog mouse models. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
Catalog table
| Model | Type | Category | Availability | Catalog # | Action |
|---|---|---|---|---|---|
| R26-CAG-LSL-Foxk1-2A-tdtomato | KI | Overexpression, Fluorescent Model | EMBRYO | KI 200314 | Inquire |
| A CAG-LSL-Foxk1-2A-tdtomato-WPRE-pA expression cassette was knocked into the Rosa26 locus. | |||||
| R26-CAG-LSL-ASGR1-2A-ASGR2 | KI | Other | DEVELOPING | KI 264070 | Inquire |
| CAG-LSL-Kozak-ASGR1-P2A-ASGR2-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-CDK3 | KI | Other | DEVELOPING | KI 263582 | Inquire |
| CAG-LSL-Kozak-CDK3-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-hSOX2-IRES-Luc-2A-EGFP/Kras-LSL-G12D | KI | Overexpression, Fluorescent Model, Target-Humanized, Disease Model | SPERM | KI 234153 | Inquire |
| The R26-CAG-LSL-hSOX2-IRES-Luc-2A-EGFP(KI 210138) was crossed with Kras-LSL-G12D(KI 190003) to generate R26-CAG-LSL-hSOX2-IRES-Luc-2A-EGFP/Kras-LSL-G12D mice. | |||||
| R26-CAG-LSL-Luc-2A-EGFP/Trp53-Flox/Kras-LSL-G12D | KI | CKO, Point Mutation, Overexpression, Fluorescent Model, Disease Model | EMBRYO | KI 234519 | Inquire |
| The R26-CAG-LSL-Luc-2A-EGFP(KI 190095) was crossed with Trp53-Flox/Kras-LSL-G12D(CKO 233079) to generate R26-CAG-LSL-Luc-2A-EGFP/Trp53-Flox/Kras-LSL-G12D mice. | |||||
| R26-CAG-LSL-AAVR | KI | Overexpression, Disease Model | EMBRYO | KI 190099 | Inquire |
| These mice harbor a SA-FRT-2XpA-CAG-FRT-LSL-AAVR-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hRHOA*Y42C-IRES-tdTomato | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | SPERM | KI 200048 | Inquire |
| These mice harbor a SA-FRT-2xpolyA-CAG-FRT-RHOA(Y42C)-IRES-tdTomato-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-Vegfc-IRES-Luc-2A-tdTomato | KI | Overexpression, Fluorescent Model, Disease Model | EMBRYO | KI 200039 | Inquire |
| These mice harbor a SA-Frt-2xpA-CAG-Frt-LSL-Vegfc-IRES-Luc-2A-tdTomato-Wpre-pA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-Hgf-IRES-Luc-2A-tdTomato | KI | Overexpression, Fluorescent Model, Disease Model | SPERM | KI 200037 | Inquire |
| These mice harbor a SA-FRT-2xpolyA-CAG-FRT-loxp-stop-loxp-Hgf-IRES-Luciferase-2A-tdTomato-wpre-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hPLA2R1-IRES-EGFP | KI | Overexpression, Fluorescent Model, Target-Humanized | LIVE | KI 220264 | Inquire |
| CAG-LSL-hPLA2R1-IRES-EGFP expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-hMSLN CDS-IRES-Luc | KI | Overexpression, Fluorescent Model, Target-Humanized | SPERM | KI 225094 | Inquire |
| CAG-LSL-hMSLN CDS-IRES-Luciferase-WPRE-pA expression cassette was knocked into the Rosa26 locus. | |||||
| R26-CAG-LSL-Mettl14-IRES-EGFP | KI | Overexpression, Fluorescent Model | EMBRYO | KI 190017 | Inquire |
| These mice harbor a SA-2xpolyA-CAG-LSL-3xFLAG-Mettl14-IRES-EGFP-Wpre-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hHER2*ex20ins-IRES-Luc-2A-EGFP | KI | Overexpression, Fluorescent Model, Target-Humanized, Disease Model | SPERM | KI 190071 | Inquire |
| These mice harbor a CAG-LSL-ERBB2(exon20 insertion)-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hEGFR-IRES-Luc-2A-tdTomato | KI | Overexpression, Fluorescent Model, Target-Humanized, Disease Model | EMBRYO | KI 190066 | Inquire |
| These mice harbor a CAG-LSL-EGFR-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hTERT-IRES-Luc-2A-EGFP | KI | Overexpression, Fluorescent Model, Target-Humanized | LIVE | KI 18035 | Inquire |
| A CAG promoter-loxp-stop-loxp-V5-TERT-IRES-Luciferase-2A-EGFP-WPRE-polyA expression cassette was inserted at the Rosa26 locus site. | |||||
| R26-CAG-LSL-Dusp12 | KI | Overexpression | EMBRYO | KI 18038 | Inquire |
| A CAG promoter-LSL-Kozak-Dusp12-3XFlag-Wpre-pA expression cassette was inserted at the Rosa26 locus site. | |||||
| R26-CAG-LSL-GqDREADD(hM3Dq)-2A-mCitrine | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | LIVE | KI 190106 | Inquire |
| These mice harbor a CAG-LSL-HA-GiDREADD(hM3Dq)-P2A-mCitrine-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-GiDREADD(hM4Di)-2A-mCitrine | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | LIVE | KI 190093 | Inquire |
| These mice harbor a CAG-LSL-HA-GiDREADD(hM4Di)-2A-mCitrine-WPRE-pA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-Wtap-IRES-EGFP | KI | Overexpression, Fluorescent Model | EMBRYO | KI 190058 | Inquire |
| These mice harbor a CAG-LSL-Wtap-3xFLAG-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-Ythdf1-IRES-EGFP | KI | Overexpression, Fluorescent Model | SPERM | KI 190061 | Inquire |
| These mice harbor a CAG-LSL-3xFLAG-Ythdf1-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-Ythdc2-IRES-EGFP | KI | Overexpression, Fluorescent Model | EMBRYO | KI 190060 | Inquire |
| These mice harbor a CAG-LSL-Ythdc2-3xFLAG-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hEZH2*Y646N-IRES-Luc-2A-tdTomato | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | SPERM | KI 190073 | Inquire |
| These mice harbor a CAG-LSL-EZH2(Y646N)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-SA-rtTA | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | EMBRYO | KI 18025 | Inquire |
| These mice harbor a SA-V5-M2rtTA-FRT-WPRE-FRT-polyA-attb-PGK-Neo-polyA-attp expression cassette in mouse Rosa26 loci homologous recombination. | |||||
| R26-CAG-LSL-mCherry-EGFP-LC3 | KI | Overexpression, Fluorescent Model | LIVE | KI 00124 | Inquire |
| The CAG promoter-loxp-stop-loxp-mCherry-EGFP-Map1lc3a-WPRE-polyA expression cassette was inserted into the Rosa26 gene locus by homologous recombination. Map1lc3a, also known as LC3, is a widely expressed autophagic vesicle-specific marker. There was no abnormality in heterozygous mice. The presence of the loxp-stop-loxp expression cassette prevented the transcription of the downstream target gene LC3. After mating with Cre mice, LC3 gene is driven by the CAG promoter to express mCherry and EGFP in a pH-dependent manner in phagocytic cells after ischemic injury in the progeny double positive mice. The two co-expressed fluorescent signals vary depending on the acidic environment of the autophagic vesicles within the cell. mCherry is stable in an acidic environment (pKa 4.5), and quenching occurs in the acidic environment (pKa 5.9) of EGFP in lysosomes. In the autophagy vesicles with higher pH, the fluorescence of GFP and mCherry superimposed on yellow fluorescence; while in the lower pH lysosome, EGFP was quenched and only red fluorescence signal was detected. It can be used to label and track LC3 and study the origin, progression and disappearance of autophagy in various tissues after ischemic injury. | |||||
| R26-CAG-LSL-hEML4/ALK*F1174L-Luc-tdTomato | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | EMBRYO | KI 190010 | Inquire |
| A SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-Luciferase-2A-tdTomato-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the EML4-ALK(F1174L) protein. | |||||
| R26-LSL-hEZH2-IRES-Luc-2A-tdTomato | KI | Overexpression, Fluorescent Model, Target-Humanized | SPERM | KI 18053 | Inquire |
| A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human EZH2 cDNA-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that human EZH2 could be expressed after exposure to Cre recombinase. | |||||
| R26-CAG-LSL-hNFE2L2*G81S-IRES-Luc-2A-tdTomato | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | EMBRYO | KI 190077 | Inquire |
| These mice harbor a CAG-LSL-NFE2L2(G81S)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hPIK3CA*H1047R-IRES-Luc-2A-tdTomato | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | LIVE | KI 190065 | Inquire |
| These mice harbor a CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hEGFR*L858R/T790M/C797S-IRES-Luc-2A-tdTomato | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | LIVE | KI 190067 | Inquire |
| These mice harbor a CAG-LSL-EGFR (L858R-T790M-C797S)-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hPIK3CA*H1047R-IRES-Luc-2A-tdTomato/R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc/Krt14-CreERT2 | KI | Point Mutation, Overexpression, Cre/Dre Toolbox, Fluorescent Model, Target-Humanized | EMBRYO | KI 234954 | Inquire |
| The R26-CAG-LSL-hPIK3CA*H1047R-IRES-Luc-2A-tdTomato(KI 190065)was crossed with R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc/Krt14-CreERT2(KI 234663)to generate Trp53-LSL-R172H/R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc/Krt14-CreERT2 mice. | |||||
| R26-CAG-LSL-Kras*G12C-IRES-Luc/R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc/Krt14-CreERT2 | KI | Point Mutation, Overexpression, Cre/Dre Toolbox, Fluorescent Model | LIVE | KI 235082 | Inquire |
| The R26-CAG-LSL-Kras*G12C-IRES-Luc (KI 200323) was crossed with R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc/Krt14-CreERT2 (KI 234663) to generate R26-CAG-LSL-Kras*G12C-IRES-Luc/R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc/Krt14-CreERT2 mice. | |||||
| R26-CAG-LSL-SLFN12 | KI | Other | DEVELOPING | KI 263534 | Inquire |
| CAG-LSL-Kozak-SLFN12-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Crlf1 | KI | Other | DEVELOPING | KI 263525 | Inquire |
| CAG-LSL-Kozak-Crlf1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-hCRLF1 | KI | Target-Humanized | DEVELOPING | KI 263524 | Inquire |
| CAG-LSL-Kozak-hCRLF1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-SV40T-IRES-hTERT | KI | Target-Humanized | DEVELOPING | KI 263308 | Inquire |
| CAG-LSL-Kozak-SV40T-IRES-hTERT-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-LSL-SV40T-IRES-hTERT | KI | Target-Humanized | DEVELOPING | KI 263307 | Inquire |
| SA-LSL-Kozak-SV40T-IRES-hTERT-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-hCD58 | KI | Target-Humanized, Overexpression | DEVELOPING | KI 263230 | Inquire |
| hCD58 expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-U6-gRNA(Fah)-U6-gRNA(Rag2)-U6-gRNA(IL2rg)-CAG-LSL-Cas9-2A-EGFP | KI | Other | DEVELOPING | KI 263216 | Inquire |
| U6-gRNA(Fah)-U6-gRNA(Rag2)-U6-gRNA(IL2rg)-CAG-LSL-Cas9-2A-EGFP expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-attB | KI | Overexpression | DEVELOPING | KI 263215 | Inquire |
| attB expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Luc | KI | Other Toolbox (non-Cre, non-Fluorescent), Overexpression | DEVELOPING | KI 263211 | Inquire |
| CAG-LSL-Kozak-Luciferase-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-hINSR | KI | Overexpression, Target-Humanized | DEVELOPING | KI 262954 | Inquire |
| CAG-LSL-Kozak-hINSR-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-hINSR-D734A | KI | Overexpression, Target-Humanized, Point Mutation | DEVELOPING | KI 262953 | Inquire |
| CAG-LSL-Kozak-hINSR-D734A-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Mst1r-M1231T | KI | Overexpression | DEVELOPING | KI 262920 | Inquire |
| CAG-LSL-Mst1r-M1231T-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Ube2v1 | KI | Overexpression | IN PRODUCTION | KI 262450 | Inquire |
| CAG-LSL-Kozak-Ube2v1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-RSR-LSL-PhiYFP | KI | Fluorescent Model | IN PRODUCTION | KI 262435 | Inquire |
| CAG-RSR-LSL-Kozak-PhiYFP-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-RSR-FSF-loxP-tdTomato-loxP-mNeonGreen | KI | Overexpression, Fluorescent Model | IN PRODUCTION | KI 261790 | Inquire |
| CAG-RSR-FSF-loxP-Kozak-tdTomato-WPRE-pA-loxP-Kozak-mNeonGreen-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Slco1a1-tdTomato-LSL-CAG | KI | Overexpression, Fluorescent Model | LIVE | KI 260668 | Inquire |
| CAG-LSL-Kozak-Slco1a1-pA-INS-INS-pA-tdTomato-Kozak-lox2272-STOP-lox2272-CAG expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-2xpA-CAG-LSL-hPNPLA3-IRES-EGFP | KI | Overexpression, Fluorescent Model, Target-Humanized | IN PRODUCTION | KI 260672 | Inquire |
| SA-FRT-2xpA-CAG-FRT-LSL-Kozak-hPNPLA3-IRES-EGFP-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-MitoTimer | KI | Overexpression, Fluorescent Model | IN PRODUCTION | KI 260078 | Inquire |
| CAG-LSL-Kozak-MitoTimer-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-mFerritin-Slco1a1-RSR-CAG | KI | Overexpression | IN PRODUCTION | KI 260038 | Inquire |
| CAG-LSL-Kozak-mFerritin-pA-INS*2-pA-Slco1a1-Kozak-RSR-CAG expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-FKBPv-CASP8-FLAG-IRES-EGFP | KI | Overexpression, Fluorescent Model | IN PRODUCTION | KI 260027 | Inquire |
| SA-FRT-2xpA-CAG-FRT-LSL-Kozak-Myr-FKBPv-Linker-CASP8-3×FLAG-IRES-EGFP-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Tet2 | KI | Overexpression | IN PRODUCTION | KI 254274 | Inquire |
| CAG-LSL-Kozak-Tet2-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Nat10 | KI | Overexpression | IN PRODUCTION | KI 254273 | Inquire |
| CAG-LSL-Kozak-Nat10-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Slc23a2 | KI | Overexpression | LIVE | KI 254271 | Inquire |
| CAG-LSL-Kozak-Slc23a2-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Rgs1 | KI | Overexpression | IN PRODUCTION | KI 254270 | Inquire |
| CAG-LSL-Kozak-Rgs1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Piezo1 | KI | Overexpression | LIVE | KI 254269 | Inquire |
| CAG-LSL-Kozak-Piezo1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Ogt | KI | Overexpression | LIVE | KI 254268 | Inquire |
| CAG-LSL-Kozak-Ogt-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Cdkn2a(p16) | KI | Overexpression | LIVE | KI 254267 | Inquire |
| CAG-LSL-Kozak-Cdkn2a(p16)-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Icam1 | KI | Overexpression | IN PRODUCTION | KI 254266 | Inquire |
| CAG-LSL-Kozak-Icam1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Tgfbr2 | KI | Overexpression | IN PRODUCTION | KI 254261 | Inquire |
| CAG-LSL-Kozak-Tgfbr2-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Npc1 | KI | Overexpression | IN PRODUCTION | KI 254260 | Inquire |
| CAG-LSL-Kozak-Npc1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Cdkn1a | KI | Overexpression | IN PRODUCTION | KI 254259 | Inquire |
| CAG-LSL-Kozak-Cdkn1a-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Cd36 | KI | Overexpression | IN PRODUCTION | KI 254258 | Inquire |
| CAG-LSL-Kozak-Cd36-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Arg1 | KI | Overexpression | LIVE | KI 254257 | Inquire |
| CAG-LSL-Kozak-Arg1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Apc | KI | Overexpression | IN PRODUCTION | KI 254256 | Inquire |
| CAG-LSL-Kozak-Apc-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-EGFP-ABE | KI | Overexpression, Fluorescent Model | LIVE | KI 254254 | Inquire |
| CAG-Kozak-EGFP*Q81*-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Twist1 | KI | Overexpression | IN PRODUCTION | KI 254253 | Inquire |
| CAG-LSL-Kozak-Twist1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Rbpj | KI | Overexpression | IN PRODUCTION | KI 254252 | Inquire |
| CAG-LSL-Kozak-Rbpj-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Ptk2 | KI | Overexpression | IN PRODUCTION | KI 254251 | Inquire |
| CAG-LSL-Kozak-Ptk2-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Spp1 | KI | Overexpression | LIVE | KI 254250 | Inquire |
| CAG-LSL-Kozak-Spp1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Ifnar1 | KI | Overexpression | IN PRODUCTION | KI 254249 | Inquire |
| CAG-LSL-Kozak-Ifnar1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Gja1 | KI | Overexpression | LIVE | KI 254248 | Inquire |
| CAG-LSL-Kozak-Gja1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Runx1 | KI | Overexpression | IN PRODUCTION | KI 254247 | Inquire |
| CAG-LSL-Kozak-Runx1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Trim25 | KI | Overexpression | IN PRODUCTION | KI 254246 | Inquire |
| CAG-LSL-Kozak-Trim25-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Slc16a1 | KI | Overexpression | LIVE | KI 254245 | Inquire |
| CAG-LSL-Kozak-Slc16a1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Nr1d1 | KI | Overexpression | IN PRODUCTION | KI 254244 | Inquire |
| CAG-LSL-Kozak-Nr1d1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Mpc1 | KI | Overexpression | IN PRODUCTION | KI 254243 | Inquire |
| CAG-LSL-Kozak-Mpc1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Lag3 | KI | Overexpression | LIVE | KI 254242 | Inquire |
| CAG-LSL-Kozak-Lag3-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Apoe | KI | Overexpression | IN PRODUCTION | KI 254241 | Inquire |
| CAG-LSL-Kozak-Apoe-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Htr1a | KI | Overexpression | IN PRODUCTION | KI 254240 | Inquire |
| CAG-LSL-Kozak-Htr1a-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Adrb2 | KI | Overexpression | IN PRODUCTION | KI 254239 | Inquire |
| CAG-LSL-Kozak-Adrb2-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Acsl4 | KI | Overexpression | IN PRODUCTION | KI 254238 | Inquire |
| CAG-LSL-Kozak-Acsl4-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Slc6a6 | KI | Overexpression | IN PRODUCTION | KI 254237 | Inquire |
| CAG-LSL-Kozak-Slc6a6-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Igf1 | KI | Overexpression | LIVE | KI 254236 | Inquire |
| CAG-LSL-Kozak-Igf1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Glp1r | KI | Overexpression | IN PRODUCTION | KI 254235 | Inquire |
| CAG-LSL-Kozak-Glp1r-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Lrg1 | KI | Overexpression | LIVE | KI 254230 | Inquire |
| CAG-LSL-Kozak-Lrg1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Ramp1 | KI | Overexpression | IN PRODUCTION | KI 254229 | Inquire |
| CAG-LSL-Kozak-Ramp1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Gdf15 | KI | Overexpression | IN PRODUCTION | KI 254228 | Inquire |
| CAG-LSL-Kozak-Gdf15-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Cx3cr1 | KI | Overexpression | IN PRODUCTION | KI 254227 | Inquire |
| CAG-LSL-Kozak-Cx3cr1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Il4ra | KI | Overexpression | IN PRODUCTION | KI 254226 | Inquire |
| CAG-LSL-Kozak-Il4ra-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Cd44 | KI | Overexpression | IN PRODUCTION | KI 254225 | Inquire |
| CAG-LSL-Kozak-Cd44-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Il15ra | KI | Overexpression | IN PRODUCTION | KI 254220 | Inquire |
| CAG-LSL-Kozak-Il15ra-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-Metrnl | KI | Overexpression | SPERM | KI 254108 | Inquire |
| Metrnl expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-RSR-Apoe | KI | Overexpression | LIVE | KI 253900 | Inquire |
| CAG-LSL-RSR-Kozak-Apoe-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-chPLA2R1-IRES-EGFP(BALB/c) | KI | Overexpression, Fluorescent Model | LIVE | KI 253775 | Inquire |
| CAG-LSL-Kozak-chPLA2R1-IRES-EGFP-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-H2B-EBFP-CAG-RSR-tdTomato | KI | Overexpression, Fluorescent Model | LIVE | KI 253635 | Inquire |
| CAG-LSL-Kozak-H2B-EBFP-pA-CAG-RSR-Kozak-tdTomato-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-iCasp9 | KI | Overexpression | IN PRODUCTION | KI 253332 | Inquire |
| CAG-LSL-Kozak-iCasp9-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-hPLA2R1(BALB/c) | KI | Overexpression, Target-Humanized | LIVE | KI 253107 | Inquire |
| CAG-loxP-STOP-loxP-Kozak-hPLA2R1-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-loxP-tdTomato-3xpA-lox2272-Luc-IRES-TAG-loxP-lox2272 | KI | Overexpression, Fluorescent Model | IN PRODUCTION | KI 253000 | Inquire |
| SA-loxP-tdTomato-3xpA-lox2272-WPRE-pA-Luciferase-IRES-TAG-loxP-lox2272 expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-EGFP(M-NSG,2) | KI | Overexpression, Fluorescent Model, Immunodeficient | LIVE | KI 252815 | Inquire |
| CAG-EGFP-WPRE-polyA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-FLEX-DUX4 | KI | Overexpression | DEVELOPING | KI 252778 | Inquire |
| SA-loxP-STOP-lox2272-DUX4-loxP-lox2272 expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-C3a-IRES-EGFP | KI | Overexpression, Fluorescent Model | SPERM | KI 252689 | Inquire |
| CAG-loxP-STOP-loxP-Kozak-C3a-IRES-EGFP-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-C5a-IRES-tdTomato | KI | Overexpression, Fluorescent Model | LIVE | KI 252688 | Inquire |
| CAG-loxP-STOP-loxP-Kozak-C5a-IRES-tdTomato-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-SA-2xpA-CAG-LSL-hEGFR*del19*T790M | KI | Point Mutation, Overexpression, Target-Humanized | LIVE | KI 252661 | Inquire |
| SA-2xpA-CAG-loxP-STOP-loxP-Kozak-hEGFR*del19*T790M-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-hEGFR*del19(2) | KI | Point Mutation, Overexpression, Target-Humanized | SPERM | KI 252642 | Inquire |
| CAG-loxP-STOP-loxP-Kozak-hEGFR*del19-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-Insulator-Insulator-CAG-loxP-STOP-lox2272-mCitrine-2A-GqDREADD(hM3Dq)-HA-loxP-lox2272-Insulator-Insulator | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | LIVE | KI 252625 | Inquire |
| Insulator-Insulator-CAG-loxP-STOP-lox2272-mCitrine-P2A-GqDREADD(hM3Dq)-HA-Kozak-loxP-lox2272-WPRE-pA-Insulator-Insulator expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-U6-gRNA(Trp53)-U6-gRNA(Pten)-U6-gRNA(APC)-CAG-LSL-Cas9-2A-EGFP | KI | Overexpression, Fluorescent Model | DEVELOPING | KI 252339 | Inquire |
| U6-U6-gRNA1(Trp53)-U6-gRNA2(Trp53)-U6-gRNA1(Pten)-U6-gRNA2(Pten)-CAG-LSL-Cas9-2A-EGFP expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-U6-gRNA(Trp53)-U6-gRNA(Pten)-CAG-LSL-Cas9-2A-EGFP | KI | Overexpression, Fluorescent Model | DEVELOPING | KI 252338 | Inquire |
| R26-U6-gRNA1(Trp53)-U6-gRNA2(Trp53)-U6-gRNA1(Pten)-U6- gRNA2(Pten)-U6-gRNA1(APC)-U6-gRNA2(APC)-CAG-LSL-Cas9-2A-EGFP expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Cdk5-2A-EGFP | KI | Overexpression, Fluorescent Model | SPERM | KI 252112 | Inquire |
| CAG-LSL-Kozak-Cdk5-2A-EGFP-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-LSL-RNR-IRES-hFLT3LG-FRT-WPRE-FRT(M-NSG) | KI | Overexpression, Target-Humanized, Immunodeficient | SPERM | KI 242456 | Inquire |
| The SA-loxP-STOP-loxP-rox-Neo-rox-IRES-hFLT3LG-FRT-WPRE-FRT-polyA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-mCherry-EGFP-FIS1(mito-QC) | KI | Overexpression, Fluorescent Model | LIVE | KI 242695 | Inquire |
| The CAG-LSL-Kozak-mCherry-EGFP-FIS1-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-Cyb5r4 | KI | Overexpression | SPERM | KI 241685 | Inquire |
| The CAG-LSL-Kozak-Cyb5r4-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-hygro-puro-Neo-BSD | KI | Overexpression | DEVELOPING | KI 241892 | Inquire |
| The CMV-GAL4-UAS-hygro-pA-UAS-puro-pA-UAS-Neo-pA-UAS-BSD-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-Ccr5 | KI | Overexpression | SPERM | KI 241910 | Inquire |
| The CAG-Kozak-Ccr5-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-RSR-tdTomato-2A-DTR | KI | Overexpression, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent) | LIVE | KI 200191 | Inquire |
| This mouse was obtained by crossing R26-(CAG-LSL-RSR-tdTomato-2A-DTR) mice with systemic Cre mice. | |||||
| R26-SA-LSL-DTR-IRES-tdTomato | KI | Overexpression, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent) | LIVE | KI 210136 | Inquire |
| A SA-LSL-DTR-IRES-tdTomato expression cassette was knocked into via the Rosa26 locus. | |||||
| R26-LSL-Notch1C-IRES-nEGFP | KI | Overexpression, Fluorescent Model, Disease Model | SPERM | KI 200036 | Inquire |
| These mice harbor a SA-LSL-Notch1C-IRES-nEGFP cassette in the Rosa26 locus generated by homologous recombination.Notch1C (mouse Notch1 ,amino acids 1749–2293) | |||||
| R26-CAG-LSL-hEGFR*L858R/T790M-IRES-Luc-2A-tdTomato | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | LIVE | KI 190068 | Inquire |
| These mice harbor a CAG-LSL-EGFR (L858R-T790M)-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-Luc-tdTomato | KI | Overexpression, Fluorescent Model | LIVE | KI 18051 | Inquire |
| A CAG-loxP STOP-loxP-luci-2A-tdTomato-WPRE-polyA cassette was knocked into the mouse ROSA26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that luciferase and tdTomato fluorescent protein could be expressed for cell tracing. | |||||
| R26-CAG-Cas9 | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | LIVE | KI 00120 | Inquire |
| These mice were established by crossing R26-(CAG-LSL-Cas9) and EIIA mice together. | |||||
| R26-CAG-LSL-Cas9-IRES-Luc | KI | Overexpression, Fluorescent Model | LIVE | KI 18002 | Inquire |
| These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Cas9 gene followed by IRES-Luciferase coexpression cassette. The targeted mutation was inserted into the Rosa26 locus by homologous recombination. | |||||
| R26-CAG-Luc-2A-tdTomato(M-NSG) | KI | Overexpression, Fluorescent Model, Immunodeficient | LIVE | KI 233090 | Inquire |
| The CAG-Luciferase-2A-tdTomato-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-RSR-tdTomato-2A-DTR | KI | Overexpression, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent) | LIVE | KI 190086 | Inquire |
| These mice harbor a CAG-LSL-RSR-tdTomato-2A-DTR cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-Alkbh5-IRES-EGFP | KI | Overexpression, Fluorescent Model | SPERM | KI 190054 | Inquire |
| These mice harbor a CAG-LSL-Alkbh5-3xFLAG-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-EGFP(3) | KI | Overexpression, Fluorescent Model | LIVE | KI 190090 | Inquire |
| These mice harbor a CAG-EGFP-WPRE-polyA cassette in the Rosa26 locus.2 generated by homologous recombination. While R26-CAG-EGFP(Stock No.KI 190088) and R26-CAG-EGFP(2)(Stock No.KI 190089) function similarly to R26-CAG-EGFP(3) mice,for more detailed information please contact our technical advisor. | |||||
| R26-CAG-LSL-3xNLS-endAsCas12a-3xHA-2xNLS-VPR-IRES-EGFP | KI | Overexpression, Fluorescent Model | SPERM | KI 233616 | Inquire |
| The CAG-loxP-STOP-loxP-3xNLS-endAsCas12a-3xHA-2xNLS-VPR-IRES-EGFP-bGH-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-Thy1 | KI | Overexpression | SPERM | KI 232890 | Inquire |
| The CAG-Kozak-Thy1-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-loxP-STOP-lox2272-tdTomato-IRES-Eda-loxP-lox2272 | KI | Overexpression, Fluorescent Model | SPERM | KI 232907 | Inquire |
| The CAG-loxP-STOP-lox2272-pA-WPRE-tdTomato-IRES-Eda-Kozak-loxP-lox2272 expression cassette was knocked into the R26 locus. | |||||
| R26-LSL-Mito EGFP | KI | Overexpression, Fluorescent Model | LIVE | KI 231934 | Inquire |
| The CAG-loxP-STOP-loxP-EGFP-OMM-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-3xNLS-AsCas12a-ultra-3xHA-2xNLS-2A-EGFP | KI | Overexpression, Fluorescent Model | SPERM | KI 233390 | Inquire |
| The CAG-loxP-STOP-loxP-3xNLS-AsCas12a-ultra-3xHA-2xNLS-T2A-EGFP-bGH-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-RSR-ZsGreen-Insulator-CAG-LSL-tdTomato | KI | Overexpression, Fluorescent Model | LIVE | KI 233483 | Inquire |
| The CAG-RSR-ZsGreen-WPRE-pA-Insulator-CAG-LSL-tdTomato-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-U6-gRNA(Tgm3) | KI | Overexpression | DEVELOPING | KI 220496 | Inquire |
| U6-gRNA(Tgm3) expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-pAlb-TK-IRES-Luc-2A-EGFP(NOD-scid) | KI | Overexpression, Fluorescent Model, Immunodeficient | EMBRYO | KI 18040 | Inquire |
| These Nod-Scid mice harbor a cassette containing Alb promoter-TK-IRES-luciferase-2A-EGFP-polyA. The targeted mutation was inserted into the Gt(ROSA)26Sor locus. | |||||
| R26-CAG-LSL-dCas9-SPH-IRES-EGFP | KI | Overexpression, Fluorescent Model | SPERM | KI 250714 | Inquire |
| The CAG-LSL-Kozak-dCas9-SPH-IRES-EGFP-WPRE-polyA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-Nrg1 | KI | Overexpression | LIVE | KI 250689 | Inquire |
| The CAG-LSL-Kozak-Nrg1-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-Lyve1-FLAG | KI | Overexpression | SPERM | KI 251391 | Inquire |
| The CAG-LSL-Kozak-Lyve1-FLAG-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-hPROCR | KI | Overexpression, Target-Humanized | SPERM | KI 240013 | Inquire |
| The SA-FRT-2xpA-CAG-FRT-LSL-Kozak-hPROCR-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-TrimE | KI | Overexpression | DEVELOPING | KI 232223 | Inquire |
| The CAG-LSL-TrimE expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-Tir-D4 | KI | Overexpression | IN PRODUCTION | KI 232222 | Inquire |
| The CAG-LSL-Tir-D4 expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-neo-longstop-linker-neo-longstop-Kras*G12D-FLAG-AID-EGFP-ALFA-tag | KI | Point Mutation, Overexpression, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent) | IN PRODUCTION | KI 234477 | Inquire |
| The CAG-neo-longstop-linker-neo-longstop-Kras*G12D-FLAG-AID-EGFP-ALFA-tag-Wpre-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-neo-longstop-linker-neo-longstop-FLAG-AID-EGFP-ALFA-tag | KI | Overexpression, Fluorescent Model | DEVELOPING | KI 234476 | Inquire |
| The CAG-neo-longstop-linker-neo-longstop-FLAG-AID-EGFP-ALFA-tag-Wpre-pA expression cassette was knocked into the R26 locus. | |||||
| R26-mU6-gRNA(Tyr)1-mU6-gRNA(Tyr)2-CAG-Cas9 | KI | Overexpression | DEVELOPING | KI 234337 | Inquire |
| The mU6-gRNA(Tyr)1-mU6-gRNA(Tyr)2-Ins-CAG-Cas9-WPRE-polyA expression cassette was knocked into the R26 locus. | |||||
| R26-U6-gRNA(Tgm3)1-U6-gRNA(Tgm3)2-CAG-Cas9 | KI | Overexpression | DEVELOPING | KI 234336 | Inquire |
| The U6-gRNA(Tgm3)1-U6-gRNA(Tgm3)2-Ins-CAG-Cas9-WPRE-polyA expression cassette was knocked into the R26 locus. | |||||
| R26-loxp2217-mU6-gRNA(lep)1-mU6-gRNA(lep)2-loxp-CAG-Cas9 | KI | Overexpression | DEVELOPING | KI 234335 | Inquire |
| The loxp2217-mU6-gRNA(lep)1-mU6-gRNA(lep)2-loxp-Ins-CAG-Cas9-WPRE-polyA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-MRGPRX4 | KI | Overexpression, Target-Humanized | SPERM | KI 234360 | Inquire |
| The SA-FRT-2xpA-CAG-FRT-LSL-Kozak-MRGPRX4-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-hTSHRa(BALB/c) | KI | Overexpression, Target-Humanized | SPERM | KI 234654 | Inquire |
| The CAG-loxP-STOP-lox2272-hTSHRa-loxP-lox2272-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-APEX2-Linker1-3xHA-Linker1-3c-Linker1-3xMyc-Linker2-Map1lc3b (CDS+3'UTR) | KI | Overexpression | SPERM | KI 234893 | Inquire |
| The CAG-LSL-Kozak-APEX2-Linker1-3xHA-Linker1-3c-Linker1-3xMyc-Linker2-Map1lc3b (CDS+3'UTR)-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-ITK-SYK-IRES-EGFP | KI | Overexpression, Fluorescent Model | SPERM | KI 240829 | Inquire |
| The SA-FRT-2xpA-CAG-FRT-LSL-ITK-SYK-IRES-EGFP-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-nTnG | KI | Overexpression, Fluorescent Model | SPERM | KI 240767 | Inquire |
| The CAG-loxP-H2B-tdTomato-pA-loxP-H2B-eGFP-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-MYOC mutant-3xFlag-linker-3xHA | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | SPERM | KI 240582 | Inquire |
| The CAG-MYOC mutant-3xFlag-linker-3xHA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-KikGR | KI | Overexpression, Fluorescent Model | LIVE | KI 240597 | Inquire |
| The CAG-LSL-Kozak-KikGR-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-OsTIR1(F74G)-3xFLAG | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | SPERM | KI 240363 | Inquire |
| The CAG-LSL-Kozak-OsTIR1(F74G)-3xFLAG-WPRE-polyA expression cassette was knocked into the R26 locus. | |||||
| R26-SA-CAG-LSL-HHLA2 | KI | Overexpression, Target-Humanized | SPERM | KI 240341 | Inquire |
| The SA-FRT-2xpA-CAG-FRT-LSL-HHLA2-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-Arl13b-Linker-mCherry-CAG-LSL-EGFP-CETN2 | KI | Overexpression, Fluorescent Model | SPERM | KI 241383 | Inquire |
| The CAG-LSL-Kozak-Arl13b-Linker-mCherry-WPRE-pA-CAG-lox2272-STOP-lox2272-Kozak-EGFP-CETN2-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-Usp13 | KI | Overexpression | SPERM | KI 241264 | Inquire |
| The CAG-loxP-STOP-loxP-Usp13-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-sfGFP-KASH | KI | Overexpression, Fluorescent Model | SPERM | KI 241231 | Inquire |
| The CAG-LSL-Koazk-superfolder GFP-KASH-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-Cxcl13 | KI | Overexpression | SPERM | KI 241879 | Inquire |
| The CAG-loxP-STOP-loxP-Cxcl13-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-SLIT3*R1479C | KI | Point Mutation, Overexpression | SPERM | KI 225092 | Inquire |
| CAG-LSL-SLIT3*R1479C-WPRE-pA expression cassette was knocked into the Rosa26 locus. | |||||
| R26-CAG-LSL-RSR-DTA | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | SPERM | KI 225080 | Inquire |
| CAG-LSL-RSR-DTA-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-IL37 | KI | Overexpression | SPERM | KI 225079 | Inquire |
| CAG-LSL-IL37-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-Metrnl | KI | Overexpression | SPERM | KI 225077 | Inquire |
| CAG-Metrnl-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-PhiC31-ERT2 | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | SPERM | KI 230051 | Inquire |
| CAG-Loxp-STOP-Loxp-PhiC31-ERT2-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-SA-LSL-hMycRTG3-ERT2-IRES-EGFP | KI | Overexpression, Fluorescent Model, Target-Humanized | SPERM | KI 225096 | Inquire |
| SA-loxp-stop-loxp-hMycRTG3-ERT2-IRES-EGFP-WPRE-pA expression cassette was knocked into the Rosa26 locus. | |||||
| R26-SA-Loxp-PGK-Neo-Loxp-Pik3ca-H1047R | KI | Point Mutation, Overexpression, Disease Model | LIVE | KI 225095 | Inquire |
| SA-Loxp-PGK-Neo-pA-Loxp-Pik3ca-H1047R-pA expression cassette was knocked into the Rosa26 locus. | |||||
| R26-LSL-hIGF1R-IRES-EGFP | KI | Overexpression, Fluorescent Model, Target-Humanized | SPERM | KI 231795 | Inquire |
| The CAG-LSL-Kozak-hIGF1R-IRES-EGFP-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-hFCGR3A-IRES-tdTomato | KI | Overexpression, Fluorescent Model, Target-Humanized | EMBRYO | KI 200255 | Inquire |
| A SA-FRT-2xpolyA-CAG-FRT-loxp-stop-loxp-FCGR3A-IRES-tdTomato-WPRE-polyA expression cassette was knocked into the Rosa26 locus via CRISPR/Cas9 mediated recombination. | |||||
| R26-CAG-LSL-OsTir1-9xMyc | KI | Overexpression | SPERM | KI 220389 | Inquire |
| CAG-loxP-STOP-loxP-Kozak-OsTir1-9xMyc-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Ppdpf | KI | Overexpression | SPERM | KI 234713 | Inquire |
| The CAG-loxP-STOP-loxP-Kozak-Ppdpf-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-Cpf1-IRES-EGFP | KI | Overexpression, Fluorescent Model | SPERM | KI 234699 | Inquire |
| The CAG-loxP-Neo-STOP-Neo-STOP-loxP-Kozak-Cpf1-IRES-EGFP-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-Trp53-IRES-EGFP | KI | Overexpression, Fluorescent Model | SPERM | KI 234413 | Inquire |
| The CAG-LSL-Trp53-IRES-EGFP-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-EML4-ALK-IRES-Luc-2A-Tdtomato | KI | Overexpression, Fluorescent Model | SPERM | KI 225040 | Inquire |
| CAG-FRT-loxp-stop-loxp-EML4-ALK-IRES-Luciferase-2A-Tdtomato-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Trim11 | KI | Overexpression | SPERM | KI 233701 | Inquire |
| The CAG-LSL-Kozak-Trim11-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-hEGFRvIII-IRES-Luc | KI | Overexpression, Fluorescent Model, Target-Humanized | SPERM | KI 233898 | Inquire |
| The CAG-LSL-Kozak-hEGFRvIII-IRES-Luc-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-LSL-hNTN1 | KI | Overexpression, Target-Humanized | SPERM | KI 233967 | Inquire |
| The SA-LSL-Kozak-hNTN1-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-loxP-RSR-loxP-STOP-rox-DTA | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | SPERM | KI 233974 | Inquire |
| The CAG-loxP-rox-STOP-rox-loxP-STOP-rox-DTA-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-rtTA | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | SPERM | KI 232260 | Inquire |
| The CAG-M2rtTA-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-Hif3a | KI | Overexpression | SPERM | KI 233049 | Inquire |
| The CAG-LSL-Hif3a-WPRE-pA expression cassette was knocked into the R26 locus. | |||||
| R26-PGK-Puro-polyA | KI | Overexpression | SPERM | KI 232839 | Inquire |
| The PGK-Puro-polyA-PGK-Puro-polyA-PGK-Puro-polyA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-Il33-IRES-tdTomato | KI | Overexpression, Fluorescent Model | EMBRYO | KI 200053 | Inquire |
| These mice harbor a SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-Il33-IRES-tdTomato -WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-U6-Luc3.12 gRNA-CAG-Cas13b | KI | Overexpression, Fluorescent Model | SPERM | KI 200264 | Inquire |
| These mice harbor a U6-Luc3.12 gRNA-CAG-Cas13b cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-Armc12-IRES-tdTomato | KI | Overexpression, Fluorescent Model | EMBRYO | KI 200290 | Inquire |
| A CAG-LSL-Armc12-IRES-tdTomato-Wpre-pA expression cassette was knocked into the Rosa26 locus via CRISPR/Cas9 mediated recombination. | |||||
| R26-CAG-LSL-Tgfa-IRES-Luc-2A-EGFP | KI | Overexpression, Fluorescent Model, Disease Model | EMBRYO | KI 200038 | Inquire |
| These mice harbor a SA-Frt-2xpA-CAG-Frt-LSL-Tgfa-IRES-Luc-2A-EGFP-Wpre-pA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hCD63-copGFP | KI | Overexpression, Fluorescent Model, Target-Humanized | SPERM | KI 200044 | Inquire |
| These mice harbor a pCAG-FRT-loxp-stop-loxp-hCD63-copGFP-6xHis-WPRE-polyA-FRT cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-DreERT2 | KI | Overexpression, Cre/Dre Toolbox | SPERM | KI 200040 | Inquire |
| These mice harbor a SA-FRT-2xpolyA-CAG-FRT-DreERT2-Rox-WPRE-Rox-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-loxP-tdTomato-loxP-DTA | KI | Overexpression, Fluorescent Model | LIVE | KI 225003 | Inquire |
| SA-loxP-tdTomato-PGK-Neo-3xpA-loxP-DTA-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-ZsGreen-DTA | KI | Overexpression, Fluorescent Model | LIVE | KI 225002 | Inquire |
| CAG-zsGreen-DTA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CreERT2(2) | KI | Overexpression, Cre/Dre Toolbox | SPERM | KI 220020 | Inquire |
| SA-FRT-CreERT2-Rox-WPRE-Rox-polyA expression cassette was knocked into the the Rosa26 locus. While R26-CreERT2(Stock No.KI 200041) mice function similarly to R26-CreERT2(2) mice,for more detailed information please contact our technical advisor. | |||||
| R26-CAG-LSL-PyMT-IRES-Luc-2A-EGFP | KI | Overexpression, Fluorescent Model | EMBRYO | KI 190111 | Inquire |
| These mice harbor a CAG-LSL-PyMT-IRES-Luc-2A-EGFP-Wpre-pA conditional expression cassette in mouse Rosa26 loci via CRISPR/Cas mediated homologous recombination. | |||||
| R26-CAG-LSL-hMLL-AF9-IRES-Luc-2A-tdTomato | KI | Overexpression, Fluorescent Model, Target-Humanized, Disease Model | EMBRYO | KI 190114 | Inquire |
| These mice harbor a SA-Frt-pA-CAG-Frt-LSL-MLL-AF9-IRES-Luc-2A-tdTomato-WPRE-pA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hSOS-F-tdTomato | KI | Overexpression, Fluorescent Model, Target-Humanized, Disease Model | EMBRYO | KI 200020 | Inquire |
| These mice harbor a SA-FRT-2xpolyA-CAG-FRT-loxp-Stop-loxp-SOS-F-IRES-tdTomato-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-Resp18-IRES-tdTomato | KI | Overexpression, Fluorescent Model | SPERM | KI 200270 | Inquire |
| CAG-LSL-Resp18-IRES-tdTomato-WPRE-polyA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-hSOD1*G94A-IRES-EGFP | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | SPERM | KI 200263 | Inquire |
| A CAG-FRT-LSL- SOD1(G94A)-IRES-EGFP-WPRE-pA expression cassette was knocked into the Rosa26 locus. | |||||
| R26-CAG-LSL-Kdm7a-2A-tdTomato | KI | Overexpression, Fluorescent Model | LIVE | KI 200297 | Inquire |
| A CAG-LSL-Kdm7a-2A-tdTomato-Wpre-pA expression cassette was knocked into the Rosa26 locus. | |||||
| R26-LSL-Atad3a-IRES-tdTomato | KI | Overexpression, Fluorescent Model | SPERM | KI 225045 | Inquire |
| LSL-Atad3a-IRES-tdTomato expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-OVA-Luc-IRES-tdTomato | KI | Overexpression, Fluorescent Model | SPERM | KI 200230 | Inquire |
| These mice harbor a SA-FRT-2xpolyA-CAG-FRT-loxp-stop-loxp-OVA-IRES-Luciferase-2A-tdTomato-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hFCGR2A-IRES-EGFP | KI | Overexpression, Fluorescent Model, Target-Humanized | EMBRYO | KI 200229 | Inquire |
| These mice harbor a SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-FCGR2A-IRES-EGFP-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-U6-mcherry gRNA-CAG-Cas13d | KI | Overexpression, Fluorescent Model | EMBRYO | KI 200268 | Inquire |
| These mice harbor a U6-mcherry gRNA-CAG-Cas13d cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-U6-mcherry gRNA-CAG-Cas13b | KI | Overexpression, Fluorescent Model | SPERM | KI 200266 | Inquire |
| These mice harbor a U6-mcherry gRNA-CAG-Cas13b cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hFGFR2-IRES-Luc-2A-EGFP | KI | Overexpression, Fluorescent Model, Target-Humanized, Disease Model | EMBRYO | KI 190007 | Inquire |
| A SA-2xpolyA-CAG-LSL-FGFR2-IRES-luciferase-2A-EGFP-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the FGFR2 protein. | |||||
| R26-LSL-Luc-2A-tdTomato | KI | Overexpression, Fluorescent Model | SPERM | KI 225044 | Inquire |
| LSL-Luciferase-2A-tdTomato expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Cas13d-IRES-tdTomato | KI | Overexpression, Fluorescent Model | SPERM | KI 190063 | Inquire |
| These mice harbor a CAG-LSL-Cas13d-IRES-tdTomato cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-Ythdf3-IRES-EGFP | KI | Overexpression, Fluorescent Model | EMBRYO | KI 190062 | Inquire |
| These mice harbor a CAG-LSL-3xFLAG-Ythdf3-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-Ythdc1-IRES-EGFP | KI | Overexpression, Fluorescent Model | EMBRYO | KI 190059 | Inquire |
| These mice harbor a CAG-LSL-Ythdc1-3xFLAG-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-LSL-CD3e-VL1-IRES-EGFP | KI | Overexpression, Fluorescent Model | SPERM | KI 190100 | Inquire |
| These mice harbor a SA-LSL-CD3e-VL1-IRES-EGFP-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hTPM3-NTRK1-IRES-Luc-2A-tdTomato | KI | Overexpression, Fluorescent Model, Target-Humanized, Disease Model | SPERM | KI 190098 | Inquire |
| These mice harbor a SA-polyA-CAG-LSL-TPM3-NTRK1-IRES-luc-2A-tdTomato-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-dCas9-IRES-EGFP | KI | Overexpression, Fluorescent Model | EMBRYO | KI 18031 | Inquire |
| A CAG promoter-loxp-stop-loxp-Avi tag-dCas9-IRES-EGFP-WPRE-polyA expression cassette was inserted at the Rosa26 locus site. | |||||
| R26-LSL-CD3e-VL2-IRES-EGFP | KI | Overexpression, Fluorescent Model | SPERM | KI 190108 | Inquire |
| These mice harbor a SA-loxp-STOP-loxp-CD3e-VL2-IRES-EGFP- WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hETV6/NTRK3-IRES-Luc-2A-tdTomato | KI | Overexpression, Fluorescent Model, Target-Humanized | SPERM | KI 190107 | Inquire |
| These mice harbor a SA-polyA-CAG-LSL-ETV6-NTRK3-IRES-luc-2A-tdTomato-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-zsGreen-tdTomato | KI | Overexpression, Fluorescent Model | SPERM | KI 225043 | Inquire |
| CAG-FRT-zsGreen-FRT-tdTomato expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-ChR2-H134R-tdTomato | KI | Point Mutation, Overexpression, Fluorescent Model | LIVE | KI 190113 | Inquire |
| These mice harbor a CAG-LSL-chR2(H134R)-tdTomato-WPRE-pA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-Tlr4 | KI | Overexpression | EMBRYO | KI 190112 | Inquire |
| These mice harbor a CAG-LSL-Tlr4-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-EGFP(2) | KI | Overexpression, Fluorescent Model | SPERM | KI 190089 | Inquire |
| These mice harbor a CAG-EGFP-WPRE-polyA cassette in the Rosa26 locus.1 generated by homologous recombination. While R26-CAG-EGFP(Stock No.KI 190088) and R26-CAG-EGFP(3)(Stock No.KI 190090) function similarly to R26-CAG-EGFP(2) mice,for more detailed information please contact our technical advisor. | |||||
| R26-CAG-EGFP | KI | Overexpression, Fluorescent Model | SPERM | KI 190088 | Inquire |
| These mice harbor a SA-2xpA-CAG-EGFP-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. While R26-CAG-EGFP(2)(Stock No.KI 190089) and R26-CAG-EGFP(3)(Stock No.KI 190090) function similarly to R26-CAG-EGFP mice,for more detailed information please contact our technical advisor. | |||||
| R26-CAG-LSL-Virma-IRES-EGFP | KI | Overexpression, Fluorescent Model | SPERM | KI 190057 | Inquire |
| These mice harbor a CAG-LSL-Virma-3xFLAG-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-Mettl3-IRES-EGFP | KI | Overexpression, Fluorescent Model | SPERM | KI 190056 | Inquire |
| These mice harbor a CAG-LSL-3xFLAG-Mettl3-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-Fto-IRES-EGFP | KI | Overexpression, Fluorescent Model, Disease Model | EMBRYO | KI 190055 | Inquire |
| These mice harbor a CAG-LSL-3xFLAG-Fto-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hIDH2*R172K-IRES-Luci-2A-tdTomato | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | SPERM | KI 190076 | Inquire |
| These mice harbor a CAG-LSL-IDH2(R172K)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hFGFR2*S320C-IRES-Luc-2A-EGFP | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | EMBRYO | KI 190079 | Inquire |
| These mice harbor a CAG-LSL-FGFR2(S320C)-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hFGFR3*S249C-IRES-Luc-2A-EGFP | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | EMBRYO | KI 190082 | Inquire |
| These mice harbor a CAG-LSL-FGFR3(S249C)-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hFGFR3*K562E-IRES-Luc-2A-EGFP | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | EMBRYO | KI 190081 | Inquire |
| These mice harbor a CAG-LSL-FGFR3(K562E)-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-RNR-GFPDTR | KI | Overexpression, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent) | SPERM | KI 18013 | Inquire |
| These mice harbor a SA-Rox-Neo-Rox-GFPDTR-Frt-Wpre-Frt-pA expression cassette in mouse Rosa26 loci via homologous recombination. | |||||
| R26-CAG-2xKRAB-dCas9-IRES-EGFP | KI | Overexpression, Fluorescent Model | LIVE | KI 18007 | Inquire |
| These mice harbor a CAG-LSL-2xKRAB-dCas9-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via homologous recombination. This strain can be used in CRISPR mediated target gene transcriptional inhibition (CRISPRi). The loxp-stop-loxp cassette was deleted. | |||||
| R26-LSL-PhiC31 | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | SPERM | KI 00088 | Inquire |
| These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven PhiC31 gene. The targeted mutation was inserted into the Gt(ROSA)26Sor locus. | |||||
| R26-CAG-Luc-2A-EGFP | KI | Overexpression, Fluorescent Model | LIVE | KI 00087 | Inquire |
| This R26-(CAG-Luc-EGFP) strain was generated by crossing R26-(CAG-LSL-Luc-EGFP)(KI 190095) mice with Ddx4-Cre mice. | |||||
| R26-CAG-LSL-hNRF2-IRES-Luc-2A-tdTomato | KI | Overexpression, Fluorescent Model, Target-Humanized | SPERM | KI 18050 | Inquire |
| A SA-2xpolyA-CAG-LSL-human NRF2-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus . This strain of mice can be mated with mice expressing Cre recombinase to express human NRF2 and a reporter gene in certain cells or tissues that expressing Cre recombinase. | |||||
| R26-CAG-LSL-tdTomato | KI | Overexpression, Fluorescent Model | SPERM | KI 225042 | Inquire |
| CAG-LSL-tdTomato expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Itpr1-tdTomato | KI | Overexpression, Fluorescent Model | EMBRYO | KI 18046 | Inquire |
| These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Itpr1-3xFlag-IRES-tdTomato expression cassette. The targeted mutation was inserted into the Gt(ROSA)26Sor locus. | |||||
| R26-CAG-LSL-hEGFR*T790M-IRES-Luc-2A-tdTomato | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | SPERM | KI 190070 | Inquire |
| These mice harbor a CAG-LSL-EGFR(T790M)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-Clover-Geminin(1-110)-2A-mKO2-Cdt(30-120) | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | EMBRYO | KI 200008 | Inquire |
| These mice harbor a SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-Clover-Geminin(1-110)-P2A-mKO2-Cdt(30-120)-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-mTurquoise2-SLBP(18-126)-2A-H1-mMaroon1 | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | EMBRYO | KI 200007 | Inquire |
| These mice harbor a SA-Frt-2xpolyA-CAG-Frt-LSL-mTurquoise2-SLBP(18-126)-P2A-H1-mMaroon1-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-TetO-Dre-IRES-mtagBFP2 | KI | Overexpression, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent) | LIVE | KI 190020 | Inquire |
| The SA-polyA-Ins-Ins-TetO-Dre-IRES-BFP-polyA-Ins-Ins cassette is inserted in mouse Rosa26 loci. | |||||
| R26-CAG-LSL-Ythdf2-IRES-EGFP | KI | Overexpression, Fluorescent Model | SPERM | KI 190018 | Inquire |
| These mice harbor a SA-2xpolyA-CAG-LSL-3xFLAG-Ythdf2-IRES-EGFP-Wpre-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hREST4-IRES-EGFP | KI | Overexpression, Fluorescent Model, Target-Humanized | SPERM | KI 200052 | Inquire |
| These mice harbor a CAG-LSL-REST4-IRES-EGFP-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hREST-IRES-tdTomato | KI | Overexpression, Fluorescent Model, Target-Humanized | EMBRYO | KI 200051 | Inquire |
| These mice harbor a CAG-LSL-REST-IRES-tdTomato-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hMYCN-IRES-BFP | KI | Overexpression, Fluorescent Model, Target-Humanized | SPERM | KI 225000 | Inquire |
| CAG-LSL-HA-MYCN-IRES-BFP-Wpre-polyA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-LSL-hIL15-Flag-IRES-EGFP | KI | Overexpression, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent), Target-Humanized | SPERM | KI 220130 | Inquire |
| CAG-Loxp-Stop-Loxp-Kozak-hIL2 signal peptide-hIL15-Flag-IRES-EGFP-polyA expression cassette was knocked into the the Rosa26 locus | |||||
| R26-LNL-PB | KI | Overexpression | SPERM | KI 00065 | Inquire |
| These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven piggyBac transposase. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination. PiggyBac transposase is expressed when bred to mice that express Cre recombinase. | |||||
| R26-CAG-LSL-hWNT1 | KI | Overexpression, Target-Humanized, Disease Model | SPERM | KI 190128 | Inquire |
| These mice harbor a SA-Frt-2xpA-CAG-Frt-LSL-WNT1-IRES-Luc-2A-tdTomato-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hBCR/ABL | KI | Overexpression, Target-Humanized, Disease Model | SPERM | KI 190127 | Inquire |
| These mice harbor a CAG-LSL-BCR-ABL-IRES-Luciferase-2A-tdTomato-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hPNPLA3-I148M-EGFP | KI | Overexpression, Fluorescent Model, Target-Humanized | LIVE | KI 200013 | Inquire |
| These mice harbor a SA-Frt-2xpolyA-CAG-Frt-LSL-hPNPLA3 I148M-IRES-GFP-wpre-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hTARDBP*A315T-EGFP | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | SPERM | KI 200019 | Inquire |
| These mice harbor a CAG-LSL-3xFlag-TARDBP(A315T)-IRES-GFP-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-Dre | KI | Overexpression, Cre/Dre Toolbox | SPERM | KI 200042 | Inquire |
| These mice harbor a CAG-Dre-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hDSG2 | KI | Overexpression, Target-Humanized | SPERM | KI 210444 | Inquire |
| CAG-LSL-hDSG2-WPRE-pA expression cassette was knocked into the Rosa26 locus. | |||||
| R26-CreERT2 | KI | Overexpression, Cre/Dre Toolbox | LIVE | KI 200041 | Inquire |
| These mice harbor a SA-FRT-2xpolyA-CAG-FRT-CreERT2-Rox-WPRE-Rox-polyA cassette in the Rosa26 locus generated by homologous recombination. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in multiple tissues after tamoxifen treatment. | |||||
| R26-CAG-LSL-Trem2 | KI | Overexpression | SPERM | KI 215105 | Inquire |
| CAG-Loxp-Stop-Loxp-Trem2-Wpre-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Mdfi-2A-EGFP | KI | Overexpression, Fluorescent Model | EMBRYO | KI 215104 | Inquire |
| CAG-Loxp-Stop-Loxp-Kozak-Mdfi-P2A-GFP-bGH-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-hAR-IRES-EGFP | KI | Overexpression, Fluorescent Model, Target-Humanized | SPERM | KI 215053 | Inquire |
| R26-CAG-Loxp-Stop-Loxp-hAR-IRES-EGFP-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-FCGR3A-IRES-tdTomato | KI | Overexpression, Fluorescent Model | SPERM | KI 215052 | Inquire |
| SA-FRT-2xpolyA-CAG-FRT-loxp-stop-loxp-FCGR3A-IRES-tdTomato-WPRE-polyA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Coro1a | KI | Overexpression | EMBRYO | KI 215009 | Inquire |
| A CAG-LSL-Coro1a-linker-3xFlag-HA-WPRE-pA expression cassette was knocked into the Rosa26 locus. | |||||
| R26-CAG-LSL-jGCaMP7f | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | LIVE | KI 215003 | Inquire |
| A CAG-LSL-jGCaMP7f-WPRE-pA expression cassette was knocked into the Rosa26 locus. | |||||
| R26-CAG-LSL-hPLAG1-IRES-Luc-2A-tdTomato | KI | Overexpression, Fluorescent Model, Target-Humanized | SPERM | KI 215002 | Inquire |
| A CAG-LSL-hPLAG1-IRES-Luciferase-2A-tdTomato-wpre-polyA expression cassette was knocked into the Rosa26 locus. | |||||
| R26-CAG-LSL-jRGECO1a | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | SPERM | KI 215001 | Inquire |
| A CAG-LSL-jRGECO1a-pA expression cassette was knocked into the Rosa26 locus. | |||||
| R26-CAG-LSL-SoNar | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | SPERM | KI 215000 | Inquire |
| A CAG-LSL-SoNar-WPRE-polyA expression cassette was knocked into the Rosa26 locus. | |||||
| R26-CAG-mEGFP-2A-paAIP2 | KI | Overexpression, Fluorescent Model | EMBRYO | KI 200315 | Inquire |
| A CAG-mEGFP-2A-paAIP2-Wpre-pA expression cassette was knocked into the Rosa26 locus. | |||||
| R26-CAG-LSL-mutant Ccnc-HA | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | EMBRYO | KI 210005 | Inquire |
| A CAG-LSL-mutant Ccnc-HA-Wpre-pA expression cassette was knocked into via. | |||||
| R26-CAG-LSL-Gpld1-IRES-tdTomato | KI | Overexpression, Fluorescent Model | EMBRYO | KI 210004 | Inquire |
| A CAG-LSL-Gpld1-IRES-tdTomato-Wpre-pA expression cassette was knocked into via. | |||||
| R26-CAG-LSL-Kras*G12C-IRES-Luc(BALB/c) | KI | Point Mutation, Overexpression, Fluorescent Model, Disease Model | SPERM | KI 200324 | Inquire |
| A CAG-FRT-loxp-stop-loxp-Kras(G12C)-IRES-Luciferase-polyA expression cassette was knocked into the R26 locus via CRISPR/Cas9 mediated recombination. | |||||
| R26-CAG-LSL-hCD2*C truncated | KI | Overexpression, Target-Humanized | EMBRYO | KI 200321 | Inquire |
| A CAG-LSL-hCD2 C truncated-WPRE-polyA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-hSNCA*A53T-IRES-EGFP | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | SPERM | KI 200320 | Inquire |
| A CAG-LSL-SNCA A53T-IRES-EGFP-WPRE-polyA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-SOX2-IRES-Luc-2A-EGFP | KI | Overexpression, Fluorescent Model | SPERM | KI 210138 | Inquire |
| A CAG-LSL-SOX2-IRES-Luciferase-2a-EGFP-WPRE-polyA expression cassette was knocked into via the Rosa26 locus. | |||||
| R26-CAG-LSL-hSIGLEC8-IRES-EGFP | KI | Overexpression, Fluorescent Model, Target-Humanized | EMBRYO | KI 210137 | Inquire |
| A CAG-LSL-SIGLEC8-IRES-EGFP-WPRE-polyA expression cassette was knocked into via the Rosa26 locus. | |||||
| R26-CAG-LSL-CAMK2G | KI | Overexpression | SPERM | KI 220326 | Inquire |
| CAG-loxP-STOP-loxP-CAMK2G-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-Fkbp8-IRES-EGFP | KI | Overexpression, Fluorescent Model | SPERM | KI 210135 | Inquire |
| A CAG-LSL-Fkbp8-IRES-EGFP-WPRE-polyA expression cassette was knocked into via the Rosa26 locus. | |||||
| R26-CAG-LSL-Avi-GFP-Rpl10a | KI | Overexpression, Fluorescent Model | SPERM | KI 210142 | Inquire |
| A SA-2xpolyA-CAG-LSL-Avitag-GFP-Rpl10a-WPRE-polyA expression cassette was knocked into via the Rosa26 locus. | |||||
| R26-CAG-LSL-hACE2-IRES-tdTomato | KI | Overexpression, Fluorescent Model, Target-Humanized, Disease Model | SPERM | KI 200188 | Inquire |
| These mice harbor a SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyAA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc | KI | Overexpression, Fluorescent Model, Disease Model | EMBRYO | KI 200257 | Inquire |
| A CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luciferase expression cassette was knocked into the Rosa26 locus. | |||||
| R26-LSL-SmoM2W539L-IRES-tdTomato | KI | Overexpression, Fluorescent Model, Disease Model | EMBRYO | KI 200035 | Inquire |
| These mice harbor a SA-loxp-stop-loxp-SmoM2(W539L)-IRES-tdTomato-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. W539L point mutation of the mouse gene (SmoM2), which corresponds to the W535L mutation in the human sequence. | |||||
| R26-CAG-LSL-zsGreen | KI | Overexpression, Fluorescent Model, Disease Model | LIVE | KI 200045 | Inquire |
| These mice harbor a CAG-LSL-zsGreen-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-U6-Luc3.12 gRNA-CAG-Cas13d | KI | Overexpression, Fluorescent Model | EMBRYO | KI 200265 | Inquire |
| These mice harbor a U6-Luc3.12 gRNA-CAG-Cas13d cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-loxp-tdTomato-loxp2272-Tag-IRES-EGFP-2A-Luc-loxp-loxp2272 | KI | Overexpression, Fluorescent Model, Disease Model | EMBRYO | KI 200033 | Inquire |
| These mice harbor a SA-FRT-2xpolyA-CAG-FRT-loxp-tdTomato-polyA-loxp2272-polyA-Wpre-Tag-IRES-EGFP-2A-Luciferase-loxp-loxp2272 cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-pAPOE-hCYP3A4(FVB) | KI | Overexpression, Target-Humanized | EMBRYO | KI 18032 | Inquire |
| This knock-in model was generated by inserting the human CYP3A4 cDNA driven by the liver-specific APOE promoter into the mouse Rosa26 site, which can be used to obtain liver-expressed CYP3A4 humanized model after mating with the Cyp3a13 gene and other Cyp3a family gene knockout mice. This model can be used with KI 18033 mice which has gut-specific expression of human CYP3A4 to compare the contribution of intestinal versus hepatic metabolism to the biotransformation of a test article. | |||||
| R26-CAG-LSL-hEML4/ALK-IRES-Luc-2A-tdTomato | KI | Overexpression, Fluorescent Model, Target-Humanized, Disease Model | SPERM | KI 190072 | Inquire |
| These mice harbor a CAG-LSL-EML4-ALK-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.Please check if the EML4-ALK fusion variant is what you need before ordering. | |||||
| R26-CAG-LSL-hFGFR2*W290C-IRES-Luc-2A-EGFP | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | EMBRYO | KI 190080 | Inquire |
| These mice harbor a CAG-LSL-FGFR2(W290C)-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hFGFR2*K659N-IRES-Luc-2A-EGFP | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | EMBRYO | KI 190078 | Inquire |
| These mice harbor a CAG-LSL-FGFR2(K659N)-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hIDH2*R140Q-IRES-Luc-2A-tdTomato | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | EMBRYO | KI 190075 | Inquire |
| These mice harbor a CAG-LSL-IDH2(R140Q)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hIDH1*R132H-IRES-Luc-2A-tdTomato | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | EMBRYO | KI 190074 | Inquire |
| These mice harbor a CAG-LSL-IDH1(R132H)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hFGFR3-IRES-Luc-2A-EGFP | KI | Overexpression, Fluorescent Model, Target-Humanized, Disease Model | EMBRYO | KI 190083 | Inquire |
| These mice harbor a CAG-LSL-FGFR3-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-hHER2-IRES-Luc-2A-EGFP | KI | Overexpression, Fluorescent Model, Target-Humanized, Disease Model | SPERM | KI 190008 | Inquire |
| A SA-2xpolyA-CAG-LSL-HER2-IRES-Luciferase-2A-EGFP-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the HER2 protein. | |||||
| R26-CAG-LSL-hMET-IRES-Luc-2A-tdTomato | KI | Overexpression, Fluorescent Model, Target-Humanized, Disease Model | SPERM | KI 18052 | Inquire |
| A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human cMET-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that human C-MET could be expressed after exposure to Cre recombinase. | |||||
| R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc/Krt14-CreERT2 | KI | Overexpression, Cre/Dre Toolbox, Fluorescent Model | LIVE | KI 234663 | Inquire |
| The R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc(KI 200257) was crossed with Krt14-CreERT2(KI 190024) to generate R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc/Krt14-CreERT2 mice. | |||||
| R26-pVillin1-hCYP3A4-IRES-tdTomato(FVB) | KI | Overexpression, Fluorescent Model, Target-Humanized | EMBRYO | KI 18033 | Inquire |
| Intestinal expression of the CYP3A enzyme in the human body can cause significant intestinal metabolism of the compound, resulting in impaired drug absorption. This knock-in model was generated by inserting the human CYP3A4 cDNA driven by the Villin1 promoter together with the IRES-tdTomato reporter gene into mosue Rosa26 site, which can be crossed with the Cyp3a13 gene knockout and other Cyp3a family genes knockout mice to obtain intestinal-expressed CYP3A4 humanized mouse model in order to determine the contribution of intestinal metabolism to the absorption and distribution of test article. | |||||
| R26-Renilla-Luc | KI | Overexpression, Fluorescent Model | EMBRYO | KI 00091 | Inquire |
| These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Renilla-Luc gene. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination. | |||||
| R26-CAG-LNL-CaMPARI | KI | Overexpression, Fluorescent Model | EMBRYO | KI 00090 | Inquire |
| These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven CaMPARI gene. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination. | |||||
| R26-CAG-hFcRn | KI | Overexpression, Target-Humanized | EMBRYO | KI 00081 | Inquire |
| A human FCGRT expression cassette was knocked in mouse Rosa26 loci. | |||||
| R26-U6-gRNA-Apoe-Ldlr | KI | Overexpression | EMBRYO | KI 18005 | Inquire |
| These mice harbor an U6-gRNA-Apoe-Ldlr cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-dCas9-VPR-IRES-EGFP | KI | Overexpression, Fluorescent Model | LIVE | KI 18004 | Inquire |
| These mice harbor a CAG-LSL-dCas9-VPR(VP64-p65-Rta)-eGFP-pA conditional expression cassette in mouse Rosa26 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa). | |||||
| R26-SA-BirA | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | EMBRYO | KI 00085 | Inquire |
| A SA-BirA-polyA expression cassette was knocked in mouse Rosa26 loci . Heterozygous knockin mice developed normally. | |||||
| R26-CAG-LNL-Fen1-IRES-EGFP | KI | Overexpression, Fluorescent Model | EMBRYO | KI 00126 | Inquire |
| These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Fen1 gene followed by 3xHA-IRES-EGFP tag coexpression cassette. The targeted mutation was inserted into the Rosa26 locus by homologous recombination. | |||||
| R26-CAG-LSL-NgAgo-IRES-EGFP | KI | Overexpression, Fluorescent Model | EMBRYO | KI 18011 | Inquire |
| These mice harbor a CAG-LSL-NgAgo-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via homologous recombination. | |||||
| R26-hCD46-IRES-tdTomato | KI | Overexpression, Fluorescent Model, Target-Humanized, Disease Model | EMBRYO | KI 190087 | Inquire |
| These mice harbor a SA-human CD46-IRES-tdTomato-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-Luc-2A-EGFP | KI | Overexpression, Fluorescent Model | LIVE | KI 190095 | Inquire |
| A CAG-LSL-Luciferase-2A-EGFP-wpre-polyA expression cassette was inserted at the Rosa26 locus site. | |||||
| R26-CAG-LSL-2xKRAB-dCas9-IRES-EGFP | KI | Overexpression, Fluorescent Model | LIVE | KI 220013 | Inquire |
| CAG-Loxp-Stop-Loxp-2xKRAB-dCas9-IRES-EGFP-WPRE-pA expression cassette was knocked into the the Rosa26 locus. | |||||
| R26-CAG-LSL-tdTomato-2A-DTR | KI | Overexpression, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent) | LIVE | KI 210094 | Inquire |
| These mice harbor a CAG-LSL-R-tdTomato-2A-DTR cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LSL-Kras*G12C-IRES-Luc | KI | Point Mutation, Overexpression, Fluorescent Model, Disease Model | LIVE | KI 200323 | Inquire |
| A CAG-FRT-loxp-stop-loxp-Kras(G12C)-IRES-Luciferase-polyA expression cassette was knocked into the R26 locus. | |||||
| R26-CAG-LSL-hTM6SF2*E167K-EGFP | KI | Point Mutation, Overexpression, Fluorescent Model, Target-Humanized, Disease Model | EMBRYO | KI 200017 | Inquire |
| These mice harbor a SA-Frt-2xpolyA-CAG-Frt-LSL-TM6SF2-IRES-GFP-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-CAG-LNL-ddCas9 | KI | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | EMBRYO | KI 00063 | Inquire |
| These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven ddCas9. The targeted mutation was inserted into the Gt(ROSA)26Sor locus. | |||||
| R26-CAG-LNL-Hmgb2 | KI | Overexpression | EMBRYO | KI 190130 | Inquire |
| These mice harbor a CAG-LNL-Hmgb2-3xFlag-Wpre-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
| R26-SA-LNL-C1qtnf1 | KI | Overexpression | EMBRYO | KI 190129 | Inquire |
| These mice harbor a SA-Loxp-Neo-polyA-Loxp-C1qtnf1-polyA cassette in the Rosa26 locus generated by homologous recombination. | |||||
Why this approach
Knockin and humanized formats keep regulatory context at the endogenous locus. For your target tissue focused programs, that matters when expression timing, splice isoforms, or allele dosage drive biology. Random integration transgenics can still help, but targeted alleles usually give cleaner pharmacology readouts.
Pricing and quotes
The R26 Knockin lines listed above are catalog models. Send us the catalog number and our team confirms current availability, pricing, and whether the line ships cryopreserved or live.
If your study needs a R26 allele configuration that is not listed above, our scientific team designs and generates it. Model generation quotes return in about twenty four hours with project milestones and pricing.
FAQ
What R26 Knockin mouse models are available?
When R26 Knockin lines are in catalog, we ship from inventory. If your configuration is not listed, we design the allele to order. Common paths include conditional knockout, constitutive knockout, humanized, knockin, and transgenic options, with documented germline transmission and United States QC.
Is R26 knockout embryonic lethal in mice?
It depends on background and allele design. Some R26 germline knockouts are viable. Others need conditional alleles or mixed backgrounds. We review publications and our own experience, then recommend floxed versus null before you commit.
Which Cre driver is best for experiments?
Driver choice depends on onset timing, recombination efficiency, and known leak. We map your organ and cell type to a short list of proven Cre lines, then talk through reporter crosses and controls. We favor drivers with strong community validation for your tissue.
Do you ship live R26 animals?
When catalog lines are live, we ship with health certificates and QC documentation. If your exact combo is not listed, we quote a generation project with cryo or live dispatch depending on cohort timing and geography.
How do I request a quote for R26?
Use the catalog inquire buttons or the request quote form. Include your allele goal, Cre plan if any, strain background, and cohort size. A PhD led team responds with pricing, milestones, and the fastest path to experimental animals.
Related models and routes
Breed this line with ingenious targeting laboratory
Send the R26 Knockin line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.