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R26 Xenograft-Applicable mouse models
R26 engineered hosts can be tuned for xenograft take rate and growth kinetics depending on tumor lineage.
What R26 Xenograft-Applicable mouse models are available?
ingenious targeting laboratory offers 28 distinct R26 xenograft-applicable catalog mouse models. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
Catalog table
| Model | Type | Category | Availability | Catalog # | Action |
|---|---|---|---|---|---|
| R26-CAG-LSL-Pax2/Vil1-CreERT2 | XA | CKO | DEVELOPING | XA 263573 | Inquire |
| The R26-CAG-LSL-Pax2[YZL] (CM-KI-254205) was crossed with Vil1-CreERT2(KI 225020) to generate R26-CAG-LSL-Pax2[YZL]/Vil1-CreERT2 mice. | |||||
| R26-LSL-DTR/Cx3cr1-CreERT2(2) | XA | Cre/Dre Toolbox, Other Toolbox (non-Cre, non-Fluorescent) | SPERM | XA 263549 | Inquire |
| The Cx3cr1-CreERT2 (KI 200157) was crossed with R26-LSL-DTR(NMX)(KI 192015) to generate Cx3cr1-CreERT2/R26-LSL-DTR(NMX) mice. | |||||
| R26-CAG-LSL-Nrg1/Alb-CreERT2(B6;129S) | XA | Overexpression, Cre/Dre Toolbox, Disease Model | DEVELOPING | XA 260949 | Inquire |
| The R26-CAG-LSL-Nrg1 (KI 250689) was crossed with Alb-CreERT2(KI 00002) to generate R26-CAG-LSL-Nrg1/Alb-CreERT2 mice. | |||||
| R26-LSL-Mito EGFP/Gypa-2A-tdTomato-2A-Cre | XA | Other | DEVELOPING | XA 264125 | Inquire |
| The R26-LSL-Mito EGFP (KI 231934) was crossed with Gypa-2A-tdTomato-2A-Cre(KI 253648) to generate R26-LSL-Mito EGFP/Gypa-2A-tdTomato-2A-Cre mice. | |||||
| R26-CAG-LSL-hPNPLA3-I148M-EGFP/Alb-cre-Tg | XA | Overexpression, Cre/Dre Toolbox, Fluorescent Model, Target-Humanized, Random Transgenic | LIVE | XA 242889 | Inquire |
| The R26-CAG-LSL-hPNPLA3-I148M-EGFP was crossed with Alb-cre-Tg to generate R26-CAG-LSL-hPNPLA3-I148M-EGFP/Alb-cre-Tg mice. | |||||
| R26-CAG-KikGR(2) | XA | Overexpression, Other Toolbox (non-Cre, non-Fluorescent) | LIVE | XA 242128 | Inquire |
| These mice harbor a CAG-KikGR-WPRE-pA cassette in the Rosa26 locus generated by homologous recombination | |||||
| R26-CAG-mCherry-EGFP-FIS1 | XA | Overexpression, Fluorescent Model | SPERM | XA 242794 | Inquire |
| The Dppa3-IRES-Cre(KI 00040) was crossed with R26-CAG-LSL-mCherry-EGFP-FIS1(mito-QC)(KI 242695) to generate Dppa3-IRES-Cre/R26-CAG-mCherry-EGFP-FIS1 mice. | |||||
| R26-CAG-LSL-tdTomato-2A-DTR/Folr2-CreERT2 | XA | Cre/Dre Toolbox, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent) | DEVELOPING | XA 263300 | Inquire |
| The R26-CAG-LSL-tdTomato-2A-DTR (KI 210094) was crossed with Folr2-CreERT2(KI 234021) to generate R26-CAG-LSL-tdTomato-2A-DTR/Folr2-CreERT2 mice. | |||||
| R26-CAG-LSL-hPLA2R1-IRES-EGFP/Rag2-KO | XA | Target-Humanized | DEVELOPING | XA 263247 | Inquire |
| The Rag2-KO (KO 190429) was crossed with R26-CAG-LSL-hPLA2R1-IRES-EGFP(KI 220264) to generate Rag2-KO/R26-CAG-LSL-hPLA2R1-IRES-EGFP mice. | |||||
| R26-CAG-LSL-hPIK3CA*H1047R-IRES-Luc-2A-tdTomato/Wap-IRES-Cre | XA | Point Mutation, Overexpression, Cre/Dre Toolbox, Fluorescent Model, Target-Humanized | NO F0 | XA 240830 | Inquire |
| The R26-CAG-LSL-hPIK3CA*H1047R-IRES-Luc-2A-tdTomato(KI 190065) was crossed with Wap-IRES-Cre(KI 200064) to generate R26-CAG-LSL-hPIK3CA*H1047R-IRES-Luc-2A-tdTomato/Wap-IRES-Cre mice. | |||||
| R26-CAG-EGFP(3)/hAPOE4 | XA | Overexpression, Fluorescent Model, Target-Humanized | EMBRYO | XA 252458 | Inquire |
| The hAPOE4 (HU 190002) was crossed with R26-CAG-EGFP(3)(KI 190090) to generate hAPOE4/R26-CAG-EGFP(3) mice. | |||||
| R26-CAG-EGFP(3)/hAPOE3 | XA | Overexpression, Fluorescent Model, Target-Humanized | EMBRYO | XA 252457 | Inquire |
| The hAPOE3 (HU 190003) was crossed with R26-CAG-EGFP(3)(KI 190090) to generate hAPOE3/R26-CAG-EGFP(3) mice. | |||||
| R26-CAG-EGFP(3)/hAPOE2 | XA | Overexpression, Fluorescent Model, Target-Humanized | EMBRYO | XA 252456 | Inquire |
| The hAPOE2 (HU 190013) was crossed with R26-CAG-EGFP(3)(KI 190090) to generate hAPOE2/R26-CAG-EGFP(3) mice. | |||||
| R26-CAG-RSR-ZsGreen-Insulator-CAG-LSL-tdTomato/Sox2-2A-DreERT2 | XA | Fluorescent Model, Cre/Dre Toolbox, Overexpression | DEVELOPING | XA 263072 | Inquire |
| The R26-CAG-RSR-ZsGreen-Insulator-CAG-LSL-tdTomato (KI 233483) was crossed with Sox2-2A-DreERT2(KI 200059) to generate R26-CAG-RSR-ZsGreen-Insulator-CAG-LSL-tdTomato/Sox2-2A-DreERT2 mice. | |||||
| R26-CAG-LSL-RSR-tdTomato-2A-DTR/Sox2-2A-DreERT2 | XA | Cre/Dre Toolbox, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent) | DEVELOPING | XA 263070 | Inquire |
| The R26-CAG-LSL-RSR-tdTomato-2A-DTR (KI 190086) was crossed with Sox2-2A-DreERT2(KI 200059) to generate R26-CAG-LSL-RSR-tdTomato-2A-DTR/Sox2-2A-DreERT2 mice. | |||||
| R26-CAG-LSL-RSR-tdTomato-2A-DTR/Lyz2-DreERT2 | XA | Other Toolbox (non-Cre, non-Fluorescent), Cre/Dre Toolbox, Fluorescent Model | DEVELOPING | XA 263034 | Inquire |
| The R26-CAG-LSL-RSR-tdTomato-2A-DTR (KI 190086) was crossed with Lyz2-DreERT2(KI 232418) to generate R26-CAG-LSL-RSR-tdTomato-2A-DTR/Lyz2-DreERT2 mice. | |||||
| R26-CAG-LSL-Kras*G12C-IRES-Luc/hCRBN | XA | Target-Humanized | DEVELOPING | XA 262965 | Inquire |
| The hCRBN (HU 225071) was crossed with R26-CAG-LSL-Kras*G12C-IRES-Luc(KI 200323) to generate hCRBN/R26-CAG-LSL-Kras*G12C-IRES-Luc mice. | |||||
| R26-CAG-hPNPLA3-I148M-EGFP | XA | Overexpression, Fluorescent Model, Target-Humanized | LIVE | XA 242479 | Inquire |
| The R26-CAG-LSL-hPNPLA3*I148M-EGFP(KI 200013) was crossed with Dppa3-IRES-Cre(KI 00040) to generate R26-CAG-LSL-hPNPLA3*I148M-EGFP/Dppa3-IRES-Cre mice. | |||||
| R26-CAG-Mito EGFP | XA | Overexpression, Fluorescent Model | SPERM | XA 240639 | Inquire |
| The R26-LSL-Mito EGFP (KI 231934) was crossed with Dppa3-IRES-Cre(KI 00040) to generate R26-LSL-Mito EGFP/Dppa3-IRES-Cre mice. | |||||
| R26-rtTA/TIGRE-pTRE-hDMPK(exon 11-15) | XA | Overexpression, Other Toolbox (non-Cre, non-Fluorescent), Target-Humanized | LIVE | XA 252292 | Inquire |
| The R26-rtTA (KI 232260) was crossed with TIGRE-pTRE-hDMPK(exon 11-15)(KI 232261) to generate R26-rtTA/TIGRE-pTRE-hDMPK(exon 11-15) mice. | |||||
| R26-CAG-LSL-ITK-SYK-IRES-EGFP/Cd4-CreERT2 | XA | Overexpression, Cre/Dre Toolbox, Fluorescent Model | DEVELOPING | XA 252971 | Inquire |
| The R26-CAG-LSL-ITK-SYK-IRES-EGFP (KI 240829) was crossed with Cd4-CreERT2(KI 234689) to generate R26-CAG-LSL-ITK-SYK-IRES-EGFP/Cd4-CreERT2 mice. | |||||
| R26-CAG-LSL-hTPM3-NTRK1-IRES-Luc-2A-tdTomato/Vil1-CreERT2 | XA | Overexpression, Cre/Dre Toolbox, Fluorescent Model, Target-Humanized | SPERM | XA 242228 | Inquire |
| The R26-CAG-LSL-hTPM3-NTRK1-IRES-Luc-2A-tdTomato(KI 190098) was crossed with Vil1-CreERT2(KI 225020) to generate R26-CAG-LSL-hTPM3-NTRK1-IRES-Luc-2A-tdTomato/Vil1-CreERT2 mice. | |||||
| R26-CAG-LSL-zsGreen/Scn10a-Cre(Nav1.8-Cre) | XA | Cre/Dre Toolbox, Fluorescent Model | DEVELOPING | XA 262037 | Inquire |
| The Scn10a-Cre(Nav1.8-Cre) (KI 251627) was crossed with R26-CAG-LSL-zsGreen(KI 200045) to generate Scn10a-Cre(Nav1.8-Cre)/R26-CAG-LSL-zsGreen mice. | |||||
| R26-CAG-LSL-hMSLN CDS-IRES-Luc/Msln-CreERT2 | XA | Overexpression, Cre/Dre Toolbox, Fluorescent Model, Target-Humanized | SPERM | XA 240684 | Inquire |
| The R26-CAG-LSL-hMSLN CDS-IRES-Luc(KI 225094) was crossed with Msln-CreERT2(KI 230469) to generate R26-CAG-LSL-hMSLN CDS-IRES-Luc/Msln-CreERT2 mice. | |||||
| R26-CAG-LSL-tdTomato-2A-DTR/Chat-IRES-CreERT2 | XA | Cre/Dre Toolbox, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent) | DEVELOPING | XA 261702 | Inquire |
| The R26-CAG-LSL-tdTomato-2A-DTR (KI 210094) was crossed with Chat-IRES-CreERT2(KI 242737) to generate R26-CAG-LSL-tdTomato-2A-DTR/Chat-IRES-CreERT2 mice. | |||||
| R26-CAG-LSL-chPLA2R1-IRES-EGFP/Nphs2-2A-Cre(C;BALB/c) | XA | Overexpression, Cre/Dre Toolbox, Fluorescent Model, Target-Humanized | LIVE | XA 261453 | Inquire |
| The R26-CAG-LSL-chPLA2R1-IRES-EGFP(BALB/c) (KI 253775) was crossed with Nphs2-2A-Cre(BALB/c)(KI 240824) to generate R26-CAG-LSL-chPLA2R1-IRES-EGFP(BALB/c)/Nphs2-2A-Cre(BALB/c) mice. | |||||
| R26-CAG-LSL-hPLA2R1/Nphs2-2A-Cre(BALB/c) | XA | Overexpression, Cre/Dre Toolbox, Target-Humanized | LIVE | XA 261451 | Inquire |
| The R26-CAG-LSL-hPLA2R1(BALB/c) (KI 253107) was crossed with Nphs2-2A-Cre(BALB/c)(KI 240824) to generate R26-CAG-LSL-hPLA2R1(BALB/c)/Nphs2-2A-Cre(BALB/c) mice. | |||||
| R26-rtTA/Tigre-TetO-Cas9-IRES-tdTomato | XA | Overexpression, Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent) | DEVELOPING | XA 261026 | Inquire |
| The Tigre-TetO-Cas9-IRES-tdTomato (KI 200256) was crossed with R26-rtTA(KI 232260) to generate Tigre-TetO-Cas9-IRES-tdTomato/R26-rtTA mice. | |||||
Why this approach
We help teams pick alleles that match the experimental question, the organ system, and future breeding plans. For your target tissue centric work, Cre specificity, flox placement, and baseline controls matter as much as the gene edit itself.
Pricing and quotes
The R26 Xenograft-Applicable lines listed above are catalog models. Send us the catalog number and our team confirms current availability, pricing, and whether the line ships cryopreserved or live.
If your study needs a R26 allele configuration that is not listed above, our scientific team designs and generates it. Model generation quotes return in about twenty four hours with project milestones and pricing.
FAQ
What R26 Xenograft-Applicable mouse models are available?
When R26 Xenograft-Applicable lines are in catalog, we ship from inventory. If your configuration is not listed, we design the allele to order. Common paths include conditional knockout, constitutive knockout, humanized, knockin, and transgenic options, with documented germline transmission and United States QC.
Is R26 knockout embryonic lethal in mice?
It depends on background and allele design. Some R26 germline knockouts are viable. Others need conditional alleles or mixed backgrounds. We review publications and our own experience, then recommend floxed versus null before you commit.
Which Cre driver is best for experiments?
Driver choice depends on onset timing, recombination efficiency, and known leak. We map your organ and cell type to a short list of proven Cre lines, then talk through reporter crosses and controls. We favor drivers with strong community validation for your tissue.
Do you ship live R26 animals?
When catalog lines are live, we ship with health certificates and QC documentation. If your exact combo is not listed, we quote a generation project with cryo or live dispatch depending on cohort timing and geography.
How do I request a quote for R26?
Use the catalog inquire buttons or the request quote form. Include your allele goal, Cre plan if any, strain background, and cohort size. A PhD led team responds with pricing, milestones, and the fastest path to experimental animals.
Related models and routes
Breed this line with ingenious targeting laboratory
Send the R26 Xenograft-Applicable line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.