What TIGRE Knockin mouse models are available?

When TIGRE Knockin lines are in catalog, we ship from inventory. If your configuration is not listed, we design the allele to order. Common paths include conditional knockout, constitutive knockout, humanized, knockin, and transgenic options, with documented germline transmission and United States QC.

Is TIGRE knockout embryonic lethal in mice?

It depends on background and allele design. Some TIGRE germline knockouts are viable. Others need conditional alleles or mixed backgrounds. We review publications and our own experience, then recommend floxed versus null before you commit.

Which Cre driver is best for experiments?

Driver choice depends on onset timing, recombination efficiency, and known leak. We map your organ and cell type to a short list of proven Cre lines, then talk through reporter crosses and controls. We favor drivers with strong community validation for your tissue.

Do you ship live TIGRE animals?

When catalog lines are live, we ship with health certificates and QC documentation. If your exact combo is not listed, we quote a generation project with cryo or live dispatch depending on cohort timing and geography.

How do I request a quote for TIGRE?

Use the catalog inquire buttons or the request quote form. Include your allele goal, Cre plan if any, strain background, and cohort size. A PhD led team responds with pricing, milestones, and the fastest path to experimental animals.

●11 Models Available

READY TO SHIP!

LIVE · SPERM · IN PRODUCTION

TIGRE Knockin mouse models

Browse 11 TIGRE mouse models including knockin variants — in stock and ready to ship from ingenious targeting laboratory. Request a quote within 24 hours.

Order catalog model Search All Models Request a Quote

Available TIGRE catalog models

11 TIGRE lines with QC documentation and technical support.

TIGRE-SIE-RE-Luc2
KI
Fluorescent Model
2xINS-pA-pause site-SIE-RE-Luc2-SV40 poly(A)-pA-pause site-SIE-RE-Luc2-SV40 poly(A)-pA-pause site-SIE-RE-Luc2-SV40 poly(A)-2xINS expression cassette was knocked into the the Igs7 locus.
In production — inquireKI 253948
Order
TIGRE-pTRE3G-uPA-pAlb-Tet-On 3G(M-NSG)
KI
Other Toolbox (non-Cre, non-Fluorescent), Immunodeficient
insulator-insulator-pTRE3G-uPA-pA-insulator-insulator-pAlb-Tet-On 3G-pA expression cassette was knocked into the the Igs7 locus.
In production — inquireKI 252411
Order
TIGRE-NFAT-RE-Luc2P
KI
Fluorescent Model
The 2xINS-pA-pause site-NFAT-RE-Luciferase-hPEST-SV40 poly(A)-pA-pause site-NFAT-RE-Luciferase-hPEST-SV40 poly(A)-pA-pause site-NFAT-RE-Luciferase-hPEST-SV40 poly(A)-2xINS expression cassette was knocked into the Tigre locus.
Sperm CryopreservedKI 242924
Order
TIGRE-NF-kb-RE-Luc2P
KI
Fluorescent Model
The 2xINS-pA-pause site-NF-kb-RE-Luciferase-hPEST-SV40 poly(A)-pA-pause site-NF-kb-RE-Luciferase-hPEST-SV40 poly(A)-pA-pause site-NF-kb-RE-Luciferase-hPEST-SV40 poly(A)-2xINS expression cassette was knocked into the Tigre locus.
Sperm CryopreservedKI 242923
Order
TIGRE-pMUP-uPA
KI
Other Toolbox (non-Cre, non-Fluorescent)
The insulator-insulator-pMUP-uPA-hGH-pA-insulator-insulator expression cassette was knocked into the Tigre locus.
Sperm CryopreservedKI 250281
Order
TIGRE-pTRE3G-uPA-pAlb-Tet-On 3G
KI
Other Toolbox (non-Cre, non-Fluorescent)
The insulator-insulator-pTRE3G-uPA-pA-insulator-insulator-pAlb-Tet-On 3G-pA expression cassette was knocked into the Tigre locus.
Sperm CryopreservedKI 250200
Order
TIGRE-TetO-LSL-Archon-KGC-GFP-ER2-CAG-LSL-PAmCherry-2A-tT
KI
Fluorescent Model, Other Toolbox (non-Cre, non-Fluorescent)
The TetO-LSL-Archon-KGC-GFP-ER2-CAG-LSL-PAmCherry-2A-tT expression cassette was knocked into the Tigre locus.
Sperm CryopreservedKI 240808
Order
TIGRE-TetO-Cas9TdT-CAG-LSL-rtTA
KI
Other Toolbox (non-Cre, non-Fluorescent)
The TetO-Cas9TdT-WPRE-pA-insulator-CAG-LSL-rtTA-pA expression cassette was knocked into the Tigre locus.
LiveKI 240155
Order
TIGRE-pTRE-hDMPK(exon 11-15)
KI
Target-Humanized
The 2xIns-DMPK 5‘region-pTRE-hDMPK(exon 11-15)-3'UTR(CTG)200-DMPK 1st intron-pA-2xIns expression cassette was knocked into the Tigre locus.
Sperm CryopreservedKI 232261
Order
TIGRE-Tet-Off-tTA
KI
Other Toolbox (non-Cre, non-Fluorescent)
Insx2-pTRE2-LSL-EGFP-WPRE-pA-Insx2-pCAG-LSL-tdTomato-P2A-tTA2-WPRE-pA expression cassette was knocked into the the TIGRE locus.
Sperm CryopreservedKI 225047
Order
TIGRE-Tet-On-rtTA
KI
Other Toolbox (non-Cre, non-Fluorescent)
Insx2-pTRE2-LSL-EGFP-WPRE-pA-Insx2-pCAG-LSL-tdTomato-P2A-rtTA-WPRE-pA expression cassette was knocked into the the TIGRE locus.
Sperm CryopreservedKI 225046
Order

Looking for a TIGRE mouse model?

We have 11 TIGRE models in stock — including Knockin types. In stock and ready to ship this week. All models come with full QC documentation, health certificates, and dedicated technical support.

Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.

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Models Available

Model Types

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Included

QC Documentation

About TIGRE Mouse Model Types

TIGRE knockin models carry a precisely inserted sequence at the TIGRE locus, useful for reporter, tag, or humanization studies.

Knockin Mouse Models Mouse Model Generation Services

Modifications available

Jump to catalog backed pages for TIGRE organized by modification type. Each URL is indexable and matches common search patterns.

TIGRE Knockin

Related Gene Targets

Tigar Tigit Tigre

Breed this line with ingenious targeting laboratory

Send the TIGRE line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.

Mouse Models

Two paths. One scientific team.

Search 14,774+ study ready strains, or commission the exact knockout, knockin, or humanized model your program requires.

Live colonies

TIGRE models ready to ship

Get a confirmed quote in 24 hours. All TIGRE models ship with full QC documentation, health certificates, and lifetime technical support.

TIGREStudy ready strains in catalog

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Model generation

Need a knockout, knockin, or humanized line?

Specialized conventional and conditional knockouts
Knockins including point mutations, cDNA insertions, and epitope tags
Humanized models, including partial and full gene replacements
Targeted transgenesis in safe harbor loci
Inducible/reversible alleles using advanced recombinase techniques

The same U.S. scientific team designs and delivers your allele when it is not on the shelf. 2,800+ custom models generated since 1998. 100% germline transmission guarantee.

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