What hPD Humanized mouse models are available?

When hPD Humanized lines are in catalog, we ship from inventory. If your configuration is not listed, we design the allele to order. Common paths include conditional knockout, constitutive knockout, humanized, knockin, and transgenic options, with documented germline transmission and United States QC.

Is hPD knockout embryonic lethal in mice?

It depends on background and allele design. Some hPD germline knockouts are viable. Others need conditional alleles or mixed backgrounds. We review publications and our own experience, then recommend floxed versus null before you commit.

Which Cre driver is best for experiments?

Driver choice depends on onset timing, recombination efficiency, and known leak. We map your organ and cell type to a short list of proven Cre lines, then talk through reporter crosses and controls. We favor drivers with strong community validation for your tissue.

Do you ship live hPD animals?

When catalog lines are live, we ship with health certificates and QC documentation. If your exact combo is not listed, we quote a generation project with cryo or live dispatch depending on cohort timing and geography.

How do I request a quote for hPD?

Use the catalog inquire buttons or the request quote form. Include your allele goal, Cre plan if any, strain background, and cohort size. A PhD led team responds with pricing, milestones, and the fastest path to experimental animals.

●68 Models Available

READY TO SHIP!

LIVE · SPERM · EMBRYO · DEVELOPING

hPD Humanized, Xenograft-Applicable mouse models

Browse 68 hPD mouse models including humanized, xenograft-applicable variants — in stock and ready to ship from ingenious targeting laboratory. Available as hPD humanized mouse, hPD xenograft-applicable mouse. Request a quote within 24 hours.

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Available hPD catalog models

68 hPD lines with QC documentation and technical support. hPD humanized models carry the human gene sequence for translational research.

hPD-1/hSIRPA(2)
HU
Target-Humanized
hPD-1(HU 00015) was crossed with hSIRPA(2) (HU 18015) to generate hPD-1/hSIRPA(2).
Embryo CryopreservedHU 2000089
Order
hPD-L1/hOX40
HU
Target-Humanized
hPD-L1（HU 00062）was crossed with hOX40（HU 00041）to generate hPD-L1/hOX40.
Embryo CryopreservedHU 00111
Order
hPD-L1(2)/hCD28
HU
Target-Humanized
hPD-L1(2)(HU 190039) was crossed with hCD28(HU 190011）to generate hPD-L1(2)/hCD28 mice
Embryo CryopreservedHU 210370
Order
hPD-L1/hSTING
HU
Target-Humanized
hPD-L1(HU 00062) was crossed with hSTING(HU 190036) to generate hPD-L1/hSTING.
Embryo CryopreservedHU 2000105
Order
hPD-1/hSTING
HU
Target-Humanized
hPD-1(HU 00015) was crossed with hSTING(HU 190036) to generate hPD-1/hSTING.
Embryo CryopreservedHU 2000104
Order
hPD-1(BALB/c)
HU
Target-Humanized
The endogenous mouse Pdcd1 gene was replaced by human PDCD1(PD-1) gene .
LiveHU 190079
Order
hPD-L1(E3-4)
HU
Target-Humanized
Extracellular domain of mouse Cd274(also known as PD-L1) gene was replaced by human PD-L1 gene. While hPD-L1(Stock No.HU 00062) mice function similarly to hPD-L1(2) mice,for more detailed information please contact our technical advisor.
Embryo CryopreservedHU 190039
Order
hPD-L2
HU
Target-Humanized
The endogenous mouse Pdcd1lg2 gene was replaced by the human PDCD1LG2 gene.
Embryo CryopreservedHU 190050
Order
hPD-1(3)
HU
Target-Humanized
The endogenous mouse Pdcd1 gene was replaced by human PDCD1 gene.
LiveHU 235087
Order
hPD-1/hPD-L1(2)/hCCR8
HU
Target-Humanized
hPD-1(HU 00015) and hPD-1(2)(HU 190039) were crossed with hCCR8(HU 190053) to generate hPD-1/hPD-L1(2)/hCCR8 mice.
In DevelopmentHU 210402
Order
hPD-L1/hCD27(2)
HU
Target-Humanized
hPD-L1(HU 00062) was crossed with hCD27(2)(HU 190035)to generate hPD-L1/hCD27(2) mice.While hPD-L1/hCD27 (Stock No.HU 18023) have been pulled from shelves for some reasons.
Embryo CryopreservedHU 200274
Order
hPD-L1/hCD28
HU
Target-Humanized
hPD-L1(HU 00062) was crossed with hCD28(HU 190011) to generate hPD-L1/hCD28 mice
Embryo CryopreservedHU 210019
Order
hPD-1/hPD-L1/hLAG3
HU
Target-Humanized
hPD-1(HU 00015),hPD-L1(HU 00062) were crossed with hLAG3(HU 00049) to generate hPD-1/hPD-L1/hLAG3.
Embryo CryopreservedHU 190028
Order
hPD-1/hPD-L1/hIDO1
HU
Target-Humanized
hPD-1(HU 00015),hPD-L1(HU 00062) were crossed with hIDO1(HU 00061) to generate hPD-1/hPD-L1/hIDO1.
LiveHU 00120
Order
hPD-1/Cd8a-IRES-Akaluc-2A-EGFP
HU
Fluorescent Model, Target-Humanized
hPD-1(HU 00015) was crossed with Cd8a-IRES-Luc-2A-EGFP(KI 18030) to generate hPD-1/Cd8a-IRES-Luc-2A-EGFP mice
Embryo CryopreservedHU 210373
Order
hPD-1/hPD-L1/hCD73(2)
HU
Target-Humanized
hPD-1(HU 00015) was crossed with hPD-L1/hCD73(2)(HU 210356) to generate hPD-1/hPD-L1/hCD73(2) mice.
Embryo CryopreservedHU 210410
Order
hPD-1/hTLR9
HU
Target-Humanized
hPD-1(HU 00015) was crossed with hTLR9(HU 18016) to generate hPD-1/hTLR9.
Embryo CryopreservedHU 190023
Order
hPD-1/hPVRIG
HU
Target-Humanized
The hPVRIG(HU 210008) was crossed with hPD-1(HU 00015) to generate hPD-1/hPVRIG mice.
Embryo CryopreservedHU 231147
Order
hPD-1/hCCR8(BALB/c,2)
HU
Target-Humanized
The hCCR8(BALB/c)(2)(HU 220501) was crossed with hPD-1(BALB/c)(HU 190079) to generate hPD-1/hCCR8(BALB/c,2) mice.
Embryo CryopreservedHU 234063
Order
hPD-1/hICOS(2)
HU
Target-Humanized
hPD-1(HU 00015) was crossed with hICOS(2)(HU 190030) to generate hPD-1/hICOS(2).
Embryo CryopreservedHU 2000100
Order
hPD-1/hVEGFR2
HU
Target-Humanized
hPD-1(HU 00015) was crossed with hKDR(HU 00098) to generate hPD-1/hKDR.
Embryo CryopreservedHU 2000098
Order
hPD-1/hCD28
HU
Target-Humanized
hPD-1(HU 00015) was crossed with hCD28(HU 190011) to generate hPD-1/hCD28.
Embryo CryopreservedHU 2000097
Order
hPD-1/hCD27(2)
HU
Target-Humanized
hPD-1(HU 00015) was crossed with hCD27(2)(HU 190035) to generate hPD-1/hCD27(2).
Embryo CryopreservedHU 2000096
Order
hPD-1/hSIGLEC15
HU
Target-Humanized
hPD-1(HU 00015) was crossed with hSIGLEC15(HU 190037) to generate hPD-1/hSIGLEC15.
Embryo CryopreservedHU 2000093
Order
hPD-1/hPD-L1/hPD-L2
HU
Target-Humanized
The endogenous mouse Pd-1/Pd-l1/Pdcd1lg2 gene was replaced by human PD-1/PD-L1/PDCD1LG2 gene.
Embryo CryopreservedHU 190060
Order
hPD-1/hLAG3
HU
Target-Humanized
hPD-1(HU 00015) was crossed with hLAG3(HU 00049)to generate hPD-1/hLAG3 mice
LiveHU 00101
Order
hPD-1/hPD-L1
HU
Target-Humanized
hPD-1(HU 00015) was crossed with hPD-L1(HU 00062)to generate hPD-1/hPD-L1 mice
LiveHU 00100
Order
hPD-1/hCTLA-4
HU
Target-Humanized, Disease Model
hPD-1(HU 00015) was crossed with hCTLA4(HU 00014)to generate hPD-1/hCTLA4 mice
Embryo CryopreservedHU 00079
Order
hPD-1/hCTLA-4(BALB/c)
HU
Target-Humanized
hPD-1(HU 190079) was crossed with hCTLA4(2)(HU 190078)to generate hPD-1/hCTLA4 mice
Embryo CryopreservedHU 200277
Order
hPD-1
HU
Target-Humanized
The endogenous mouse Pdcd1 gene was replaced by human PDCD1(PD-1) gene .
LiveHU 00015
Order
hPD-1/hSEMA4D
HU
Target-Humanized
hPD-1(HU 00015) was crossed with hSEMA4D(HU 00117) to generate hPD-1/hSEMA4D.
Embryo CryopreservedHU 190033
Order
hPD-1/hTIGIT/hTIM3
HU
Target-Humanized
hPD-1(HU 00015),hTIGIT(HU 00053) were crossed with hTIM3(HU 00054) to generate hPD-1/hTIGIT/hTIM3.
Embryo CryopreservedHU 190029
Order
hPD-1/hPD-L1/hTIGIT
HU
Target-Humanized
hTIGIT（HU 00053）,hPD-1（HU 00015）,hPD-L1（HU 00062）were crossed together to generate hPD-1/hPD-L1/hTIGIT mice
Embryo CryopreservedHU 200267
Order
hPD-1/hPD-L1/hCTLA-4
HU
Target-Humanized
hCTLA4（HU 00014）,hPD-1（HU 00015）,hPD-L1（HU 00062）were crossed together to generate hPD-1/hPD-L1/hCTLA4 mice
LiveHU 200266
Order
hPD-1/hPD-L1/hTIM3
HU
Target-Humanized
hTIM3（HU 00054）,hPD-1（HU 00015）,hPD-L1（HU 00062）were crossed together to generate hPD-1/hPD-L1/hTIM3 mice
Embryo CryopreservedHU 200264
Order
hPD-1/hLAG3/hTIGIT
HU
Target-Humanized
hPD-1(HU 00015),hTIGIT(HU 00053) were crossed with hLAG3(HU 00049) to generate hPD-1/hLAG3/hTIGIT.
Embryo CryopreservedHU 200258
Order
hPD-1/hIL1B
HU
Target-Humanized
hPD-1(HU 00015) was crossed with hIL1B(HU 190047) to generate hPD-1/hIL1B mice
Embryo CryopreservedHU 210018
Order
hPD-1/hCD40
HU
Target-Humanized
hPD-1(HU 00015) was crossed with hCD40(HU 00076) to generate hPD-1/hCD40.
LiveHU 190017
Order
hPD-1/hCD3E
HU
Target-Humanized
hPD-1（HU 00015）was crossed with hCD3E（HU 00114）to generate hPD-1/hCD3E。
Embryo CryopreservedHU 18021
Order
hPD-1/hTIGIT
HU
Target-Humanized
hPD-1(HU 00015) was crossed with hTIGIT(HU 00053) to generate hPD-1/hTIGIT.
Embryo CryopreservedHU 00104
Order
hPD-1/hTIM3
HU
Target-Humanized
hPD-1(HU 00015) was crossed with hTIM3(HU 00054)to generate hPD-1/hTIM3 mice
Embryo CryopreservedHU 00103
Order
hPD-1/hOX40
HU
Target-Humanized
hPD-1（HU 00015）was crossed with hOX40（HU 00041）to generate hPD-1/hOX40.
Embryo CryopreservedHU 00108
Order
hPD-L1/hVISTA
HU
Target-Humanized
hPD-L1(HU 00062) was crossed with hVISTA(HU 00118) to generate hPD-L1/hVISTA.
Embryo CryopreservedHU 2000094
Order
hPD-1/hVISTA
HU
Target-Humanized
hPD-1(HU 00015) was crossed with hSIRPA(2) (HU 18015) to generate hPD-1/hVISTA.
Embryo CryopreservedHU 2000092
Order
hPD-L1(2)/hCCR8
HU
Target-Humanized
hPD-1(2)(HU 190039) was crossed with hCCR8(HU 190053) to generate hPD-L1(2)/hCCR8 mice.
Embryo CryopreservedHU 210401
Order
hPD-1/hPD-L1/hOX40
HU
Target-Humanized
hPD-1(HU 00015),hPD-L1(HU 00062) were crossed with hOX40(HU 00041) to generate hPD-1/hPD-L1/hOX40.
Embryo CryopreservedHU 00122
Order
hPD-L2(BALB/c)
HU
Target-Humanized
The endogenous mouse Pdcd1lg2 gene was replaced by human PDCD1LG2 gene.
Embryo CryopreservedHU 190061
Order
hPD-L1/hCTLA-4
HU
Target-Humanized
hPD-L1(HU 00062) was crossed with hCTLA4(HU 00014)to generate hPD-1/hCTLA4 mice
Embryo CryopreservedHU 00102
Order
hPD-L1/hSIRPA(2)
HU
Target-Humanized
hPD-L1(HU 00062) was crossed with hSIRPA(2)(HU 18015) to generate hPD-L1/hSIRPA(2).
Embryo CryopreservedHU 2000099
Order
hPD-L1
HU
Target-Humanized
The endogenous mouse Cd274(also known as PD-L1) gene was replaced by human PD-L1 gene . While hPD-L1(2)(Stock No.HU 190039) mice function similarly to hPD-L1 mice,for more detailed information please contact our technical advisor.
LiveHU 00062
Order
hPD-L1/hSIGLEC15
HU
Target-Humanized
hPD-L1(HU 00062) was crossed with hSIGLEC15(HU 190037) to generate hPD-L1/hSIGLEC15.
Embryo CryopreservedHU 2000103
Order
hPD-L1/hVEGFR2
HU
Target-Humanized
hPD-L1(HU 00062) was crossed with hKDR(HU 00098) to generate hPD-L1/hKDR.
Embryo CryopreservedHU 2000102
Order
hPD-L1/h4-1BB(2)
HU
Target-Humanized
hPD-L1(HU 00062) was crossed with h4-1BB(2)(HU 190077) to generate hPD-L1/h4-1BB(2).
Embryo CryopreservedHU 200260
Order
hPD-L1/hCD73(2)
HU
Target-Humanized
hPD-L1(HU 00062) was crossed with hCD73(2)(HU 200009) to generate hPD-L1/hCD73(2) mice.
Embryo CryopreservedHU 210356
Order
hPD-L1/hTIM3
HU
Target-Humanized
hPD-L1(HU 00062) was crossed with hTIM3(HU 00054) to generate hPD-L1/hTIM3.
Embryo CryopreservedHU 190056
Order
hPD-L1/hSEMA4D
HU
Target-Humanized
hPD-L1(HU 00062) was crossed with hSEMA4D(HU 00117) to generate hPD-L1/hSEMA4D.
Embryo CryopreservedHU 190034
Order
hPD-L1/hTIGIT
HU
Target-Humanized
hPD-L1(HU 00062) was crossed with hTIGIT(HU 00053) to generate hPD-L1/hTIGIT.
Embryo CryopreservedHU 18013
Order
hPD-L1/hLAG3
HU
Target-Humanized
hPD-L1（HU 00062）was crossed with hLAG3（HU 00049）to generate hPD-L1/hLAG3.
Embryo CryopreservedHU 00137
Order
hPD-L1/hCD40
HU
Target-Humanized
hPD-L1(HU 00062) was crossed with hCD40(HU 00076) to generate hPD-L1/hCD40.
Embryo CryopreservedHU 18024
Order
hPD-1/hPD-L1(BALB/c)
HU
Target-Humanized
hPD-1(BALB/c)(HU 190079) mice were crossed with hPD-L1(BALB/c ) (HU 220028) mice to generate hPD-1/ hPD-L1(BALB/c) mice.
Embryo CryopreservedHU 220142
Order
hPD-L1(BALB/c)
HU
Target-Humanized
The hPD-L1(E3-4)(HU 190039) mice were backcrossed to BALB/c genetic background, to create the new strain of hPD-L1(BALB/c) (HU 220028) mice.
LiveHU 220028
Order
hPD-1/hPD-L1/HLA-A2.1/B2M
XA
Target-Humanized
The hPD-1/hPD-L1 (HU 00100) was crossed with HLA-A2.1/B2M(HU 241353) to generate hPD-1/hPD-L1/HLA-A2.1/B2M mice.
LiveXA 252092
Order
hPD-1/hTL1A(3)
XA
Target-Humanized
The hTL1A(3) (HU 233157) was crossed with hPD-1(HU 00015) to generate hTL1A(3)/hPD-1 mice.
LiveXA 251906
Order
hPD-1/hPD-L1/hMERTK
XA
Target-Humanized
The hMERTK(HU 2000031) was crossed with hPD-1/hPD-L1(HU 00100) to generate hPD-1/hPD-L1/hMERTK mice.
LiveXA 250683
Order
hPD-1/hIL21R
XA
Target-Humanized
The hIL21R(HU 210031) was crossed with hPD-1(HU 00015) to generate hPD-1/hIL21R mice.
Embryo CryopreservedXA 240522
Order
hPD-1/hVEGFA
XA
Target-Humanized
The hVEGFA(HU 2000028) was crossed with hPD-1(HU 00015) to generate hPD-1/hVEGFA mice.
LiveXA 242781
Order
hPD-L1/hVEGFA
XA
Target-Humanized
The hVEGFA (HU 2000028) was crossed with hPD-L1(HU 00062) to generate hVEGFA/hPD-L1 mice.
Sperm CryopreservedXA 252262
Order
hPD-1/hPD-L1/hTACSTD2
XA
Target-Humanized
The hTACSTD2(HU 215022) was crossed with hPD-1/hPD-L1(HU 00100) to generate hPD-1/hPD-L1/hTACSTD2 mice.
Embryo CryopreservedXA 242246
Order

Looking for a hPD mouse model?

We have 68 hPD models in stock — including Humanized, Xenograft-Applicable types. In stock and ready to ship this week. All models come with full QC documentation, health certificates, and dedicated technical support.

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About hPD Mouse Model Types

A hPD humanized mouse replaces the mouse hPD gene with the human ortholog for translational research and drug development.

Humanized Mouse Models Mouse Model Generation Services

Modifications available

Jump to catalog backed pages for hPD organized by modification type. Each URL is indexable and matches common search patterns.

hPD Humanized hPD Xenograft-Applicable

Related Gene Targets

Hpd hPDGFB hPDGFD hPDGFRA hPDGFRB Hpdl

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Send the hPD line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.

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hPD models ready to ship

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Knockins including point mutations, cDNA insertions, and epitope tags
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Inducible/reversible alleles using advanced recombinase techniques

The same U.S. scientific team designs and delivers your allele when it is not on the shelf. 2,800+ custom models generated since 1998. 100% germline transmission guarantee.

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