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huHSC Humanized, Immunodeficient mouse models
Browse 4 huHSC mouse models including humanized, immunodeficient variants — in stock and ready to ship from ingenious targeting laboratory. Available as huHSC humanized mouse, huHSC immunodeficient mouse. Request a quote within 24 hours.
Available huHSC catalog models
4 huHSC lines with QC documentation and technical support. huHSC humanized models carry the human gene sequence for translational research.
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huHSC-(Kit-V831M M-NSG)
HUImmunodeficient, Point Mutation
iTL constructed Kit-V831M(NMG) mice by replacing valine (V) with methionine (M) at amino acid position 831 of the mouse Kit gene. Based on this model, human CD34+ HSCs were transplanted into these mice.
LiveHU 263011 - Order
huHSC-(hIL3/hCSF2 M-NSG)
HUTarget-Humanized, Immunodeficient
The cytokines IL-3 and GM-CSF are involved in the proliferation and differentiation of myeloid cell precursors. NMG mice transduced with the genes encoding IL-3 and GM-CSF can achieve myeloid cell reconstitution following human hematopoietic stem cell transplantation, presenting a more complete human immune system.
LiveHU 263008 - Order
huHSC-(NVG-hIL15)
HUTarget-Humanized, Immunodeficient
Interleukin-15 (IL-15) is essential for the activity, function, and differentiation of NK cells. The expression of human IL-15 in the severely immunodeficient NMG mouse background reduces the differences in immune environment between mice and humans, provides a more suitable survival environment for NK cells, and supports the reconstitution, expansion, and long-term expression of NK cells in vivo. In addition, NVG-hIL15 also supports the reconstitution and expansion of γδ T cells, enabling successful reconstitution with a relatively low injection dose of γδ T cells and extending the survival time of T cells.
LiveHU 263007 - Order
huHSC-(M-NSG)
NSGTarget-Humanized, Immunodeficient
After irradiation, NMG mice are injected with CD34+ hematopoietic stem cells (CD34+ HSC).
In production — inquireNSG 017
Looking for a huHSC mouse model?
We have 4 huHSC models in stock — including Humanized, Immunodeficient types. In stock and ready to ship this week. All models come with full QC documentation, health certificates, and dedicated technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog modelAbout huHSC Mouse Model Types
A huHSC humanized mouse replaces the mouse huHSC gene with the human ortholog for translational research and drug development.
Modifications available
Jump to catalog backed pages for huHSC organized by modification type. Each URL is indexable and matches common search patterns.
Breed this line with ingenious targeting laboratory
Send the huHSC line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.