ingenious targeting laboratory is open and fully operational to work on new and existing animal model projects.

"A better model is within reach."

Post Project Services

Post Project

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Your important endeavor, now made seamless.

We are open and operational to work on any of these services, as well as new animal model projects, during the COVID-19 pandemic.

Genotyping Services: Now available for existing and new custom mouse models designed by ingenious. Learn more and submit an order form.

Our Post Project Services Include

  • Breeding small or large cohorts of heterozygous or homozygous mice.
  • Breeding with any Cre lines (or tTA, tTS, CreERT etc.) with your new customized mice.
  • Genotyping of all offspring with established protocols developed by ingenious.
  • Timed deliveries at your request between your control and experimental groups.
  • Alleviate the need to justify animal use protocol numbers.
  • A free online tool to generate an estimated mating plan – ingenious Breeding Planner.

Tissue Harvest: Contact us to learn more.

COVID-19 Response Services

Cryopreservation (Sperm and embryo)

Temporary housing and breeding
  • Cryopreservation
    Protect your mouse model and your research investment! We offer sperm cryopreservation and embryo cryopreservation services, various storage plans for cryopreserved sperm and embryos, and cryorecovery service to rederive your mouse line.

  • Sperm Cryopreservation

    The service includes sperm collection and cryopreservation from two male mice, including motility test of thawed sperm. Service also includes in vitro fertilization and culturing of embryos to the blastocyst stage to confirm fertility of cryopreserved sperm.

  • Embryo Cryopreservation

    This service includes sperm collection from two male mice, and subsequent in vitro fertilization of oocytes from superovulated wildtype females. Embryos will be cryopreserved. Service also includes quality control by culturing of thawed embryos to confirm viability.

    Note: Embryos will be a mix of wildtype and heterozygous genotypes when heterozygous males are used (the resulting pups must be genotyped), or all embryos will be heterozygous when homozygous males are used.

  • ES Cell Clone Storage

    We can provide extended storage of the confirmed targeted ES cell clones from your mouse model project. Extended clone storage can be applied for periods of either 3 years or 5 years at a time.

Once you receive your mouse model from ingenious, your ultimate goal will be to generate a cohort of mice of a certain age and sex, which you can then utilize for your experiments. You may continue to need more colonies as your experiments evolve. Depending on the model we have generated for you, this may require multiple mating steps, genotyping for various genetic elements, and calculated scaling up to obtain the specific number of mice with the appropriate sex, background and genotype.

We know from talking with many of our clients that traditional in-house breeding often becomes an unnecessarily expensive and time consuming process, which can even lead to the loss of the mouse line. ingenious offers downstream services to make this important endeavor seamless.

By outsourcing the generation of mouse cohorts to ingenious, you will benefit from expert staff that will work with you to determine the most efficient breeding plan to meet your research goals. Utilizing our proprietary breeding software allows us to develop plans of action based on time lines and costs that best fit your lab.