Colony Management Services
Maintaining a productive mouse colony requires consistent husbandry, accurate genotyping, and strategic breeding decisions.
Breeding Colony Maintenance
Documented pedigrees, organized mating schemes, and regular health monitoring to ensure colony productivity and genetic integrity.
Genotyping Services
PCR based assays to identify carriers, homozygotes, and compound mutants. Ingenious targeting laboratory develops generated genotyping protocols for each targeted allele.
Cohort Development
Generate study ready animals on your timeline. We can expand from founders to experimental cohorts while you focus on research design and data analysis.
Strain Background Management
Backcrossing to congenic backgrounds and speed congenic services using SNP marker panels to accelerate background conversion.
Cryopreservation Services
Cryopreservation protects your mouse lines against colony loss while reducing ongoing maintenance costs.
Sperm Cryopreservation
The most cost effective archival solution. Frozen sperm from characterized males can regenerate your line through IVF when needed.
Embryo Cryopreservation
Freezes two cell stage embryos for rapid colony recovery. This approach preserves both maternal and paternal genetics in a single archive.
targeted clone cryopreservation
Maintains characterized targeted clones for future use, enabling generation of additional mice or derivative alleles without repeating the targeting process.
Archive and Recovery
Quality controlled storage with documented inventory and validated recovery procedures to regenerate colonies from frozen stocks.
Rederivation Services
Rederivation eliminates adventitious pathogens and establishes clean health status for mouse lines.
Embryo Transfer Rederivation
Uses IVF or natural mating to generate embryos that are transferred to pathogen free recipients, producing offspring with documented clean health status.
Health Status Upgrade
Enables transfer of lines between facilities with different health barriers or recovery of lines from compromised health status.
Quarantine and Testing
Provides documented health screening before integration into clean facilities.
Speed Expansion Breeding
Accelerate timeline from founders to experimental cohorts.
Superovulation Protocols
Increase embryo yield from valuable females, accelerating colony expansion.
IVF Recovery
Rapid regeneration of archived lines from cryopreserved sperm.
Strategic Breeding Schemes
Optimize mating configurations to achieve target genotypes efficiently.
Cohort Coordination
Delivers animals at specified ages and genotypes aligned with your experimental timeline.
Service Comparison
| Service | Best For | Timeline |
|---|---|---|
| Colony Management | Ongoing breeding support | Continuous |
| Sperm Cryopreservation | Cost effective archival | 2 to 4 weeks |
| Embryo Cryopreservation | Rapid recovery needed | 4 to 6 weeks |
| Rederivation | Health status upgrade | 8 to 12 weeks |
| Speed Expansion | Accelerated cohort generation | Variable |
| Phenotyping | Model characterization | Variable |
What Researchers Say
“Our project manager did an outstanding job and has provided us with excellent customer service. Her availability to clarify issues has been nothing short of fantastic. I have recommended ingenious to others. Look forward for further collaboration on other projects.”
— Hamid M. Said, PhD, PharmD
University of California, Irvine