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H11 Xenograft-Applicable mouse models
Work with your strain choice to align human tumor models with the immune profile you need.
What H11 Xenograft-Applicable mouse models are available?
ingenious targeting laboratory offers 15 distinct H11 xenograft-applicable catalog mouse models. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
Catalog table
| Model | Type | Category | Availability | Catalog # | Action |
|---|---|---|---|---|---|
| H11-IL3-CSF2-KITLG/hIL15-TgV1(M-NSG) | XA | Target-Humanized, Immunodeficient | DEVELOPING | XA 264018 | Inquire |
| The hIL15-TgV1(NMG) (KI 220133) was crossed with H11-IL3-CSF2-KITLG(NMG)(KI 252296) to generate hIL15-TgV1(NMG)/H11-IL3-CSF2-KITLG(NMG) mice. | |||||
| H11-IL3-CSF2-KITLG/Kit-V831M(M-NSG) | XA | Target-Humanized, Immunodeficient | DEVELOPING | XA 264017 | Inquire |
| The Kit-V831M(NMG) (KI 242813) was crossed with H11-IL3-CSF2-KITLG(NMG)(KI 252296) to generate Kit-V831M(NMG)/H11-IL3-CSF2-KITLG(NMG) mice. | |||||
| H11-CAG-LSL-Myc*T58A-IRES-Luc/Trp53-Flox | XA | CKO, Point Mutation, Overexpression, Fluorescent Model | SPERM | XA 253651 | Inquire |
| Based on Trp53-Flox (CKO 18005), the CAG-LSL-Kozak-Myc*T58A-IRES-Luciferase-WPRE-pA sequence was inserted into the Igs2 locus of mice, resulting in the generation of H11-CAG-LSL-Myc*T58A-IRES-Luciferase-WPRE-pA mice with dual gene modifications of Trp53-Flox. | |||||
| H11-pAlb-hBAFF/hAPRIL | XA | Overexpression, Target-Humanized | LIVE | XA 252033 | Inquire |
| The H11-pAlb-hBAFF (KI 232137) was crossed with hAPRIL(HU 220521) to generate H11-pAlb-hBAFF/hAPRIL mice. | |||||
| H11-CAG-RSR-tdTomato/Hbb-bs-Linker-HA-2A-DreERT2 | XA | Other | DEVELOPING | XA 263935 | Inquire |
| The Hbb-bs-Linker-HA-2A-DreERT2 (KI 261391) was crossed with H11-CAG-RSR-tdTomato(KI 18009) to generate Hbb-bs-Linker-HA-2A-DreERT2/H11-CAG-RSR-tdTomato mice. | |||||
| H11-CAG-LSL-ZsGreen-CAG-RSR-tdTomato/Cdkn2a-2A-DreERT2(p16-2A-DreERT2) | XA | Overexpression, Fluorescent Model | DEVELOPING | XA 253373 | Inquire |
| The H11-CAG-LSL-ZsGreen-CAG-RSR-tdTomato (KI 200319) was crossed with Cdkn2a-2A-DreERT2(p16-2A-DreERT2)(KI 225086) to generate H11-CAG-LSL-ZsGreen-CAG-RSR-tdTomato/Cdkn2a-2A-DreERT2(p16-2A-DreERT2) mice. | |||||
| H11-pSFTPC-hTSLP/hCRLF2(BALB/c) | XA | Overexpression, Target-Humanized | DEVELOPING | XA 251534 | Inquire |
| The H11-pSFTPC-hTSLP(BALB/c) (KI 241307) was crossed with hCRLF2(BALB/c)(HU 241304) to generate H11-pSFTPC-hTSLP(BALB/c)/hCRLF2(BALB/c) mice. | |||||
| H11-pSFTPC-hTSLP/hCRLF2/hIL7R(BALB/c) | XA | Overexpression, Target-Humanized | DEVELOPING | XA 251535 | Inquire |
| The H11-pSFTPC-hTSLP/hCRLF2(BALB/c) (XA 251534) was crossed with hIL7R(BALB/c)(HU 241305) to generate H11-pSFTPC-hTSLP/hCRLF2(BALB/c)/hIL7R(BALB/c) mice. | |||||
| H11-CAG-LSL-H2B-ZsGreen/Stra8-2A-tdTomato-2A-Cre | XA | Other | DEVELOPING | XA 263714 | Inquire |
| The H11-CAG-LSL-H2B-ZsGreen (KI 260044) was crossed with Stra8-2A-tdTomato-2A-Cre(KI 225030) to generate H11-CAG-LSL-H2B-ZsGreen/Stra8-2A-tdTomato-2A-Cre mice. | |||||
| H11-IL3-CSF2-KITLG/hIL15-Tg(M-NSG) | XA | Target-Humanized, Immunodeficient | DEVELOPING | XA 264019 | Inquire |
| The hIL15-Tg(NMG) (KI 210141) was crossed with H11-IL3-CSF2-KITLG(NMG)(KI 252296) to generate hIL15-Tg(NMG)/H11-IL3-CSF2-KITLG(NMG) mice. | |||||
| H11-pSFTPC-hTSLP/hIL7R/hTSLP(BALB/c) | XA | Overexpression, Target-Humanized | DEVELOPING | XA 251526 | Inquire |
| The H11-pSFTPC-hTSLP/hTSLP(BALB/c) (XA 251525) was crossed with hIL7R(BALB/c)(HU 241305) to generate H11-pSFTPC-hTSLP/hTSLP(BALB/c)/hIL7R(BALB/c) mice. | |||||
| H11-CAG-LSL-H2B-ZsGreen/Cx3cr1-Cre | XA | Cre/Dre Toolbox, Fluorescent Model | DEVELOPING | XA 262490 | Inquire |
| The H11-CAG-LSL-H2B-ZsGreen (KI 260044) was crossed with Cx3cr1-Cre(KI 200079) to generate H11-CAG-LSL-H2B-ZsGreen/Cx3cr1-Cre mice. | |||||
| H11-pAlb-hBAFF/Itgam-IRES-hCD89/hIGHA1 | XA | Target-Humanized | DEVELOPING | XA 262029 | Inquire |
| The H11-pAlb-hBAFF (KI 232137) was crossed with Itgam-IRES-hCD89/hIGHA1(HU 210412) to generate H11-pAlb-hBAFF/Itgam-IRES-hCD89/hIGHA1 mice. | |||||
| H11-CAG-Arl13b-Linker-APEX2 | XA | Overexpression | LIVE | XA 252433 | Inquire |
| The H11-CAG-LSL-Arl13b-Linker-APEX2 (KI 241214) was crossed with Dppa3-IRES-Cre(KI 00040) to generate H11-CAG-Arl13b-Linker-APEX2 mice. | |||||
| H11-pSFTPC-hTSLP/hTSLP(BALB/c) | XA | Overexpression, Target-Humanized | DEVELOPING | XA 251525 | Inquire |
| The H11-pSFTPC-hTSLP(BALB/c) (KI 241307) was crossed with hTSLP(BALB/c)(HU 241306) to generate H11-pSFTPC-hTSLP(BALB/c)/hTSLP(BALB/c) mice. | |||||
Why this approach
We help teams pick alleles that match the experimental question, the organ system, and future breeding plans. For your target tissue centric work, Cre specificity, flox placement, and baseline controls matter as much as the gene edit itself.
Pricing and quotes
The H11 Xenograft-Applicable lines listed above are catalog models. Send us the catalog number and our team confirms current availability, pricing, and whether the line ships cryopreserved or live.
If your study needs a H11 allele configuration that is not listed above, our scientific team designs and generates it. Model generation quotes return in about twenty four hours with project milestones and pricing.
FAQ
What H11 Xenograft-Applicable mouse models are available?
When H11 Xenograft-Applicable lines are in catalog, we ship from inventory. If your configuration is not listed, we design the allele to order. Common paths include conditional knockout, constitutive knockout, humanized, knockin, and transgenic options, with documented germline transmission and United States QC.
Is H11 knockout embryonic lethal in mice?
It depends on background and allele design. Some H11 germline knockouts are viable. Others need conditional alleles or mixed backgrounds. We review publications and our own experience, then recommend floxed versus null before you commit.
Which Cre driver is best for experiments?
Driver choice depends on onset timing, recombination efficiency, and known leak. We map your organ and cell type to a short list of proven Cre lines, then talk through reporter crosses and controls. We favor drivers with strong community validation for your tissue.
Do you ship live H11 animals?
When catalog lines are live, we ship with health certificates and QC documentation. If your exact combo is not listed, we quote a generation project with cryo or live dispatch depending on cohort timing and geography.
How do I request a quote for H11?
Use the catalog inquire buttons or the request quote form. Include your allele goal, Cre plan if any, strain background, and cohort size. A PhD led team responds with pricing, milestones, and the fastest path to experimental animals.
Related models and routes
Breed this line with ingenious targeting laboratory
Send the H11 Xenograft-Applicable line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.