What HLA Humanized mouse models are available?

When HLA Humanized lines are in catalog, we ship from inventory. If your configuration is not listed, we design the allele to order. Common paths include conditional knockout, constitutive knockout, humanized, knockin, and transgenic options, with documented germline transmission and United States QC.

Is HLA knockout embryonic lethal in mice?

It depends on background and allele design. Some HLA germline knockouts are viable. Others need conditional alleles or mixed backgrounds. We review publications and our own experience, then recommend floxed versus null before you commit.

Which Cre driver is best for experiments?

Driver choice depends on onset timing, recombination efficiency, and known leak. We map your organ and cell type to a short list of proven Cre lines, then talk through reporter crosses and controls. We favor drivers with strong community validation for your tissue.

Do you ship live HLA animals?

When catalog lines are live, we ship with health certificates and QC documentation. If your exact combo is not listed, we quote a generation project with cryo or live dispatch depending on cohort timing and geography.

How do I request a quote for HLA?

Use the catalog inquire buttons or the request quote form. Include your allele goal, Cre plan if any, strain background, and cohort size. A PhD led team responds with pricing, milestones, and the fastest path to experimental animals.

●19 Models Available

HLA Humanized, Transgenic mouse models

Browse 19 HLA mouse models including humanized, transgenic variants — in stock and ready to ship from ingenious targeting laboratory. Available as HLA humanized mouse, HLA transgenic mouse. Request a quote within 24 hours.

Order catalog model Search All Models

Mouse Models

Two paths. One scientific team.

Search 14,774+ study ready strains, or commission the exact knockout, knockin, or humanized model your program requires.

Ready to ship

Search 14,774 strains. Many ship from live colonies.

Browse by gene, model type, or therapeutic area. Live colonies available for many top requested knockouts, knockins, and humanized lines.

Trp53Tumor suppressor, knockout & knockin Brca1Breast cancer model, multiple alleles Rosa26Safe harbor for reporters & cassettes

Browse Full Catalog

Model generation

Need a knockout, knockin, or humanized line?

The same U.S. scientific team designs and delivers your allele when it is not on the shelf. 100% germline transmission guarantee.

Conventional and conditional knockouts
Point mutation and humanized knockins
2,800+ models generated since 1998

Request a Quote Explore model generation services

Available HLA catalog models

19 HLA lines with QC documentation and technical support. HLA humanized models carry the human gene sequence for translational research.

HLA-B39.1/B2M
Humanized
Target humanized mice
In production — inquireHU 252702
Order
HLA-B7.2/B2M
Humanized
Target humanized mice
In production — inquireHU 252701
Order
HLA-B58.1/B2M
Humanized
Target humanized mice
In production — inquireHU 252700
Order
HLA-B40.1/B2M
Humanized
Target humanized mice
In production — inquireHU 252699
Order
HLA-DPA1/HLA-DPB1
Humanized
Target humanized mice
liveHU 234679
Order
HLA-DR1 (HLA-DRA*0101/HLA-DRB1*0101)
Humanized
Target humanized mice
In production — inquireHU 241520
Order
HLA-DQ8
Humanized
Target humanized mice
liveHU 240843
Order
HLA-G/B2M
Humanized
Target humanized mice
sperm cryopreservationHU 241967
Order
HLA-A11.1/B2M(2)
Humanized
Target humanized mice
liveHU 241354
Order
HLA-A2.1/B2M
Humanized
Target humanized mice
liveHU 241353
Order
HLA-A24.2/B2M(2)
Humanized
Target humanized mice
liveHU 241352
Order
HLA-A1.1/B2M
Humanized
Target humanized mice
liveHU 241351
Order
HLA-A3.1/B2M
Humanized
Target humanized mice
liveHU 250773
Order
HLA-A2.22/B2M
Humanized
Target humanized mice
sperm cryopreservationHU 210010
Order
HLA-A24.2/B2M(M-NSG)
Humanized
Target humanized mice, Immunodeficient mice
In production — inquireHU 252347
Order
HLA-A11.1/B2M(M-NSG)
Humanized
Target humanized mice, Immunodeficient mice
In production — inquireHU 252346
Order
HLA-A3.1/B2M(M-NSG)
Humanized
Target humanized mice, Immunodeficient mice
In production — inquireHU 252345
Order
HLA-A2.1/B2M(M-NSG)(2)
Humanized
Target humanized mice, Immunodeficient mice
liveHU 241683
Order
HLA-DQA2-Tg
Transgenic
Target humanized mice, random transgenic mice
sperm cryopreservationTG 232501
Order

Looking for a HLA mouse model?

We have 19 HLA models in stock — including Humanized, Transgenic types. In stock and ready to ship this week. All models come with full QC documentation, health certificates, and dedicated technical support.

Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.

Order catalog model

Models Available

Model Types

24 hrs

Quote Turnaround

Included

QC Documentation

About HLA Mouse Model Types

A HLA humanized mouse replaces the mouse HLA gene with the human ortholog for translational research and drug development. HLA transgenic models carry additional copies of the HLA gene for overexpression studies.

Humanized Mouse Models Transgenic Mouse Models Mouse Model Generation Services

Modifications available

Jump to catalog backed pages for HLA organized by modification type. Each URL is indexable and matches common search patterns.

HLA Humanized HLA Transgenic

Related Gene Targets

hLAG3 hLAIR1