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Grid2 Knockout mouse models

Grid2 null animals are straightforward to genotype and phenotype when survival is acceptable. They remain a standard background for pharmacology, biomarker, and rescue studies.

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Catalog table

A conventional knockout answers whether the gene is required broadly. When your target tissue is the organ of interest, a global null can still be informative if viability is acceptable and you want the simplest genotype. If the null is harsh, a floxed allele with a regional Cre is the safer long term platform.

A conventional knockout answers whether the gene is required broadly. When liver is the organ of interest, a global null can still be informative if viability is acceptable and you want the simplest genotype. If the null is harsh, a floxed allele with a regional Cre is the safer long term platform.

ModelTypeCategoryAvailabilityCatalog #Action
Grid2-KOKnockoutKO/CKO miceembryo cryopreservationKO 200981Inquire

Why this approach

A conventional knockout answers whether the gene is required broadly. When your target tissue is the organ of interest, a global null can still be informative if viability is acceptable and you want the simplest genotype. If the null is harsh, a floxed allele with a regional Cre is the safer long term platform.

A conventional knockout answers whether the gene is required broadly. When liver is the organ of interest, a global null can still be informative if viability is acceptable and you want the simplest genotype. If the null is harsh, a floxed allele with a regional Cre is the safer long term platform.

Pricing and quotes

The Grid2 Knockout lines listed above are catalog models. Send us the catalog number and our team confirms current availability, pricing, and whether the line ships cryopreserved or live.

If your study needs a Grid2 allele configuration that is not listed above, our scientific team designs and generates it. Model generation quotes return in about twenty four hours with project milestones and pricing.

Order a catalog Grid2 modelRequest a model generation quote

FAQ

Is Grid2 knockout embryonic lethal in mice?

Lethality depends on genetic background and exact allele design. Some Grid2 germline knockouts are viable, others require conditional alleles or mixed backgrounds. We review publications and our own experience, then recommend floxed versus null approaches before you commit.

Which Cre driver is best for experiments?

Driver choice depends on onset timing, recombination efficiency, and known leak patterns. We map your organ and cell type to a short list of proven Cre lines, then discuss reporter crosses and controls. We prioritize drivers with strong community validation for your tissue.

Do you ship live Grid2 animals?

When catalog lines are live, we ship with health certificates and QC documentation. If your exact combo is not listed, we quote a model generation project with cryo or live dispatch options depending on cohort timing and geography.

How do I request a quote for Grid2?

Use the catalog inquire buttons or the request quote form with your allele goal, Cre plan if any, strain background, and cohort size. A PhD led team responds with pricing, milestones, and the fastest path to experimental animals.

Related models and routes

All Grid2 models
Gria1 KnockoutGria3 KnockoutGrik1 KnockoutGrik2 KnockoutGrik4 KnockoutGrik5 KnockoutGrin2a KnockoutGrin2b Knockout

Citations