Conventional / global / constitutive KO
●2 Models Available
Fcer1g Conditional Knockout, Knockout mouse models
Browse 2 Fcer1g mouse models including conditional knockout, knockout variants — in stock and ready to ship from ingenious targeting laboratory. Available as Fcer1g conditional knockout mouse, Fcer1g knockout mouse. Request a quote within 24 hours.
Why model Fcer1g
Fcer1g, the mouse ortholog of human FCER1G, encodes the FcR gamma chain, a compact ITAM-bearing transmembrane subunit that supplies signaling competence to ligand-binding alpha chains including FcgammaRI, FcgammaRIII, FcgammaRIV, FcepsilonRI, and several PIR and OSCAR family receptors. Receptor crosslinking by immune complexes drives Src family phosphorylation of the ITAM tyrosines, Syk recruitment through tandem SH2 domains, and downstream PLCgamma2, PI3K, and Vav signaling that produces degranulation, phagocytosis, and antibody dependent cytotoxicity. Because the gamma chain is also required for surface assembly and stability of its partner alpha chains, a germline null collapses essentially all activating Fc receptor output at once, which is powerful for asking whether a phenotype is Fc dependent but useless for resolving which individual receptor carries it. Conditional deletion in myeloid or NK compartments, or reconstitution on a null background with single humanized alpha chains, keeps interpretation clean, and note that Tyrobp supplies parallel ITAM coupling for a distinct receptor set.
What Fcer1g mouse models are available?
ingenious targeting laboratory offers 2 distinct Fcer1g (FCER1G) catalog mouse models, featuring conditional knockout and standard knockout. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
| Model Availability | Allele Class Options |
|---|---|
| 2 Ready Catalog Lines | Conditional Knockout (cKO) |
| Custom Model Generation | Constitutive Knockout (KO) |
| Advanced Modifications | Humanized, Knockin, Transgenic |
- Quality Control
- Documented Germline Transmission
- Quality Control
- Strict United States QC Guidelines
- Quality Control
- Cryo or Live Dispatch Options
Fcer1g model types
PathAvailability
Knockout
Conditional knockout
Knockin
Humanized
Transgenic / overexpression
Prefer the order form? Order. Need an allele that is not listed? Request a quote.
Fcer1g allele types
Knockout, conditional, knockin, humanized, and related paths for Fcer1g (human FCER1G). Catalog lines ship when inventory exists. Everything else is a generation quote.
Knockout
Conditional KO (floxed / loxP)
Inducible conditional KO (CreER / tet)
Tissue specific KO
Specify tissue or Cre driver on quote
Knockout first (tm1a / IKMC)
Convertible floxed allele pathway
Double / compound KO
Multi allele / compound knockout project
Large scale / BAC deletion
BAC scale deletion or targeting
Knockin
Point mutation KI
cDNA KI
Reporter KI (GFP, YFP, RFP, mCherry, tdTomato, lacZ, luciferase)
Tag KI (FLAG, HA, Myc, V5)
Conditional KI (e.g. Rosa26 LSL)
LSL or conditional expression knockin
Gene replacement KI
Humanized
Full gene replacement
Partial / domain humanized
Domain or partial humanization scope
Immune checkpoint humanized
Checkpoint IO humanization when gene is a checkpoint target
Single humanized
Double / multi humanized
Multi humanized / combination IO project
Transgenic
Random integration transgenic
Safe harbor (ROSA26, HPRT, H11, Col1a1)
Overexpression transgenic
BAC transgenic
BAC transgenic or large fragment insert
Cre / recombinase
Constitutive Cre driver
Inducible Cre (CreER / tet)
Tamoxifen or dox inducible Cre
Dual recombinase (Cre+Dre / Cre+Flp)
Dual recombinase breeding scheme
Flp driver
Flp or FRT derivative allele pairing
Reporter
Reporter knockin (gene specific)
Standalone reporter catalog (lineage tracing, constitutive, dual reporter)
Catalog reporter lines not tied to a single gene allele
Species / background
Rat KO / KI / transgenic
Specify rat on quote
Rabbit models
Specify rabbit on quote
C57BL/6 (B6J / B6N)
Background substrain on quote
BALB/c
129, NOD, NSG, FVB, CD1, DBA/2
Background strain on quote
Available Fcer1g catalog models
2 Fcer1g lines with QC documentation and technical support. Fcer1g floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.
Looking for a Fcer1g mouse model?
We have 2 Fcer1g models in stock — including Conditional Knockout, Knockout types. In stock and ready to ship this week. All models come with full QC documentation, health certificates, and dedicated technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog model2
Models Available
2
Model Types
24 hrs
Quote Turnaround
Included
QC Documentation
About Fcer1g Mouse Model Types
A Fcer1g knockout mouse has the Fcer1g gene permanently inactivated, enabling loss of function studies. A Fcer1g conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Fcer1g, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints.
Modifications available
Jump to catalog backed pages for Fcer1g organized by modification type. Each URL is indexable and matches common search patterns.